Product image of Abalam-Power (Abacavir and Lamivudine ) 600mg/300mg Tablet supplied by GNH India

Abalam-Power

Active Ingredient:
Abacavir and Lamivudine
Form:
Tablet

Abalam-Power (Abacavir and Lamivudine Tablet) 600mg/300mg

ABALAM-POWER is a prescription combination antiretroviral medication containing the active ingredients abacavir (600mg) and lamivudine (300mg) in a single oral tablet. Classified as Nucleoside Reverse Transcriptase Inhibitors (NRTIs), these active substances work together to inhibit the HIV reverse transcriptase enzyme, preventing viral replication. It is used in combination with other antiretroviral agents for the management of human immunodeficiency virus type 1 (HIV-1) infection.

Strength

600mg/300mg

Pack Size

30s

Storage

Ambient

1
Pack/s
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Indications & Clinical Uses

  • ABALAM-POWER is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 25 kg. By reducing the viral load and increasing CD4 cell counts, this medication helps manage HIV-1 infection, though it is not a cure for HIV or AIDS.

Side Effects

  • Common side effects of ABALAM-POWER include nausea, headache, fatigue, insomnia, diarrhea, and dizziness. Serious adverse reactions can occur, most notably a severe and potentially life-threatening hypersensitivity reaction associated with the abacavir component, as well as lactic acidosis and severe hepatomegaly with steatosis.

Precautions & Warnings

  • Prior to initiating ABALAM-POWER, patients must be screened for the HLA-B*5701 allele, as individuals carrying this genetic marker are at a high risk of experiencing a severe hypersensitivity reaction to abacavir. Additionally, patients co-infected with hepatitis B virus (HBV) should be closely monitored, as discontinuation of lamivudine may trigger acute exacerbations of hepatitis B. This medication is classified under Pregnancy Category C and should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus.

Avoid Interactions

  • ABALAM-POWER may interact with other medications, including alcohol (which can increase abacavir levels), sorbitol-containing medicines, and other antiretrovirals like zalcitabine or emtricitabine. It is important to consult a healthcare provider before taking any concurrent prescription drugs, over-the-counter medications, or herbal supplements to avoid adverse drug interactions.

Frequently Asked Questions

ABALAM-POWER is a prescription antiretroviral tablet used in combination with other medications to treat human immunodeficiency virus type 1 (HIV-1) infection.

Each ABALAM-POWER tablet contains a combination of two active ingredients: 600mg of abacavir and 300mg of lamivudine.

Genetic testing for the HLA-B*5701 allele is required before starting ABALAM-POWER because patients with this gene have a significantly higher risk of a severe, potentially life-threatening hypersensitivity reaction to the abacavir component.

If you develop symptoms of a hypersensitivity reaction, such as fever, rash, nausea, vomiting, abdominal pain, extreme tiredness, or respiratory issues, stop taking the medication immediately and seek emergency medical attention. Do not restart the drug.

No, ABALAM-POWER does not cure HIV-1 or AIDS. It helps control the virus by lowering the viral load in the body, which supports the immune system, but patients must continue their prescribed treatment plan as directed by their healthcare provider.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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