Product image of Kopiryna – Tabletki Od Bólu Głowy (Acetylsalicylic Acid, Caffeine) supplied by GNH India

Kopiryna – Tabletki Od Bólu Głowy

Active Ingredient:
Acetylsalicylic Acid, Caffeine
Origin:
EU

Kopiryna – Tabletki Od Bólu Głowy (Acetylsalicylic Acid, Caffeine)

Acetylsalicylic acid, the active ingredient in Kopiryna – Tabletki Od Bólu Głowy, is a NSAID presented as a tablet for oral use. It treats headache, migraine, minor pain and fever in adults and adolescents.

GNH India supplies Kopiryna – Tabletki Od Bólu Głowy as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sopharma Warszawa Sp. Z O.O.

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Indications & Clinical Uses

Kopiryna combines acetylsalicylic acid and caffeine to relieve pain and fever by inhibiting prostaglandin synthesis.

  • Headache: provides rapid relief of tension‑type and mild migraine headaches.
  • Fever: reduces elevated body temperature associated with common infections.
  • Minor pain: alleviates dental, musculoskeletal and other mild pain conditions.

How It Works

  • Acetylsalicylic acid irreversibly blocks cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, lowering prostaglandin production and delivering analgesic, antipyretic and anti‑inflammatory effects. Caffeine antagonizes adenosine receptors, enhances central nervous system stimulation, and improves the absorption of aspirin, thereby augmenting its analgesic action.

Side Effects

Kopiryna may cause adverse reactions that vary in frequency and severity.

Common Side Effects

  • Nausea
  • Gastric discomfort or heartburn
  • Increased heart rate
  • Insomnia or difficulty sleeping
  • Dizziness
  • Mild headache

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration
  • Allergic reactions such as rash, angioedema, or anaphylaxis
  • Severe liver or kidney impairment
  • Tinnitus (ringing in the ears)
  • Asthma exacerbation
  • Stevens‑Johnson syndrome (very rare)

Precautions & Warnings

Before using Kopiryna, consider the following safety measures.

  • Use in adults only: not recommended for children under 12 years.
  • Avoid if known hypersensitivity to aspirin, other NSAIDs, or caffeine.
  • Caution in patients with peptic ulcer disease, gastrointestinal bleeding, or clotting disorders.
  • Monitor closely if taking anticoagulants, antiplatelet agents, or other NSAIDs.
  • Limit alcohol consumption while using this product.
  • Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Kopiryna can interact with several medicines; some require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin, direct oral anticoagulants): increased bleeding risk.
  • Other NSAIDs or corticosteroids: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.
  • Methotrexate: reduced clearance leading to toxicity.
  • Lithium: increased serum lithium concentrations.

Moderate Interactions (Monitor Closely)

  • Diuretics: possible alteration of potassium balance.
  • Antihypertensive agents: caffeine may diminish blood‑pressure‑lowering effect.
  • Antidiabetic drugs: caffeine may affect glucose control.
  • Theophylline: additive stimulant effects.
  • Oral contraceptives: potential increase in clotting risk.

Frequently Asked Questions

Kopiryna is an over‑the‑counter tablet that combines acetylsalicylic acid and caffeine to relieve headache, migraine, fever and mild to moderate pain such as dental or musculoskeletal discomfort. It is intended for adult use and provides rapid symptom relief in common everyday conditions.

Acetylsalicylic acid irreversibly inhibits the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the synthesis of prostaglandins—compounds that mediate pain, inflammation and fever. By lowering prostaglandin levels, the drug produces analgesic, antipyretic and anti‑inflammatory effects.

The appropriate dose of Kopiryna is determined by a qualified prescriber based on the individual’s age, medical condition and response to therapy. Patients should follow the healthcare professional’s instructions and never exceed the recommended amount on the product label.

Safety of Kopiryna in pregnancy or while nursing has not been established. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their healthcare provider before using this medication to weigh potential risks and benefits.

To order Kopiryna, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Kopiryna combines aspirin with caffeine, offering both anti‑platelet activity and enhanced analgesia compared with plain aspirin. Compared with ibuprofen, it may have a slightly higher risk of gastrointestinal irritation but provides a quicker onset due to caffeine. Unlike paracetamol, it has anti‑inflammatory properties but is not suitable for patients with aspirin allergy.

Store Kopiryna tablets at room temperature, preferably below 25 °C. Keep the container tightly closed, protect it from moisture, heat and direct sunlight, and store it out of reach of children.

Kopiryna is taken orally with a full glass of water. The tablet should be swallowed whole and not chewed or crushed. It can be taken with or without food, although taking it with food may reduce stomach irritation.

The most serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, and rare but serious skin conditions like Stevens‑Johnson syndrome. Patients experiencing unusual bruising, persistent stomach pain, or signs of an allergic reaction should seek medical attention promptly.

Kopiryna should be avoided by individuals with known hypersensitivity to aspirin, other NSAIDs, or caffeine; those with active peptic ulcer disease, uncontrolled bleeding disorders, severe liver or kidney impairment; and children under 12 years of age. Pregnant women and breastfeeding mothers should consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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