Product image of Koortslipcrème (Aciclovir) supplied by GNH India

Koortslipcrème

Active Ingredient:
Aciclovir
Origin:
EU

Koortslipcrème (Aciclovir)

Aciclovir, the active ingredient in Koortslipcrème, is an antiviral presented as a cream for topical use. It treats herpes simplex virus infections—including cold sores, genital herpes and shingles—by delivering the medication directly to the affected skin area in patients who need localized therapy.

GNH India supplies Koortslipcrème as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and other healthcare facilities worldwide, ensuring consistent quality and regulatory compliance across global markets through reliable logistics and dedicated customer support and timely delivery.

Manufacturer / TM Owner

Mae Holding Bv

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Indications & Clinical Uses

  • Aciclovir is an antiviral agent used to manage infections caused by the herpes simplex virus family.
  • Herpes labialis (cold sores): Reduces lesion duration and promotes faster healing when applied at the first sign of symptoms.
  • Genital herpes: Helps to alleviate outbreak severity and shorten healing time with regular topical application.
  • Herpes zoster (shingles): Provides localized antiviral activity to lessen skin lesion development and discomfort when used as directed.

How It Works

  • Aciclovir penetrates infected skin cells and is phosphorylated by viral thymidine kinase, converting it to aciclovir triphosphate. This active form competitively inhibits viral DNA polymerase, terminating DNA chain elongation and preventing replication of herpes simplex and varicella‑zoster viruses, thereby limiting lesion formation.

Side Effects

Topical application of Koortslipcrème may cause local skin reactions, although many patients experience no adverse events.

Common Side Effects

  • Mild burning or stinging at the application site
  • Redness or erythema around the treated area
  • Itching or mild pruritus
  • Dryness or flaking of the skin
  • Slight swelling or edema

Serious or Rare Side Effects

  • Allergic contact dermatitis with rash and blistering
  • Severe skin irritation or ulceration
  • Systemic hypersensitivity reactions such as urticaria
  • Unexpected worsening of lesions
  • Rare anaphylactic response requiring immediate medical attention

Precautions & Warnings

  • Before using Koortslipcrème, consider the following safety measures.
  • Avoid use on extensive damaged skin: Limit application to intact or mildly affected areas.
  • Do not apply to eyes or mucous membranes: Prevent irritation by keeping the product away from these sites.
  • Discontinue if severe irritation occurs: Seek medical advice if reactions worsen.
  • Consult a healthcare professional for pediatric use: Dosing and safety in children should be assessed by a clinician.
  • Store at below 25°C: Keep in the original tube, protect from moisture and direct sunlight.

Avoid Interactions

Koortslipcrème has limited systemic absorption, but certain co‑administered agents may influence its safety profile.

Major Interactions (Avoid)

  • Concurrent use of other topical antivirals: May increase risk of local skin irritation.
  • Systemic immunosuppressants: Could diminish overall antiviral effectiveness.

Moderate Interactions (Monitor Closely)

  • Systemic aciclovir or valacyclovir: Potential additive antiviral activity.
  • Topical corticosteroids: May mask local irritation signs.
  • Heavy moisturizers containing alcohol: Could alter cream absorption.

Frequently Asked Questions

Koortslipcrème is a topical cream containing aciclovir that is used to treat skin infections caused by the herpes simplex virus family, including cold sores (herpes labialis), genital herpes outbreaks, and shingles (herpes zoster) when applied directly to the lesions.

Aciclovir penetrates virus‑infected skin cells and is converted by viral enzymes into a triphosphate form that blocks viral DNA polymerase. This stops viral DNA synthesis, limiting replication of herpes viruses and allowing the immune system to clear the infection more effectively.

The specific amount and frequency of Koortslipcrème application are determined by the prescribing healthcare professional based on the type and severity of the lesion, patient age, and clinical guidelines. Patients should follow the prescriber’s instructions precisely.

Safety data for topical aciclovir during pregnancy and lactation are limited. Healthcare providers usually weigh the potential benefits against any unknown risks before prescribing. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss use with their doctor.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with oral antivirals such as aciclovir tablets, Koortslipcrème delivers the drug directly to the lesion, providing high local concentrations with minimal systemic exposure. It is often preferred for mild to moderate outbreaks where systemic therapy is not required.

Koortslipcrème should be stored below 25 °C in its original packaging, protected from moisture and direct sunlight. Keeping the cream at a stable, room‑temperature environment helps maintain its potency and prevents degradation.

The cream is applied thinly to clean, dry skin over the affected area, typically five times daily or as directed by a healthcare professional. Hands should be washed before and after application, and the product should not be used on open wounds or mucous membranes.

Serious risks, though rare, include severe allergic reactions such as contact dermatitis, urticaria, or anaphylaxis. If any signs of a systemic allergic response appear—such as swelling of the face, difficulty breathing, or widespread rash—medical attention should be sought immediately.

Individuals with a known hypersensitivity to aciclovir, other nucleoside analogues, or any component of the cream formulation should avoid its use. It is also contraindicated on extensively damaged or infected skin where the product cannot be applied safely.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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