Koortslipcrème Aciclovir Albert Heijn (Aciclovir)

Aciclovir is an antiviral agent that inhibits replication of herpes simplex virus.

• Herpes labialis (cold sores): shortens healing time and eases pain.
• Recurrent oral herpes: reduces frequency and severity of outbreaks.
• Primary oral herpes infection: limits lesion development and viral shedding.

• Aciclovir is a nucleoside analogue that, after intracellular phosphorylation, competitively inhibits viral DNA polymerase. This blocks the incorporation of nucleotides into viral DNA, preventing viral replication and allowing the host immune system to control the infection. The selective activation in infected cells limits effects on normal host DNA synthesis.

Topical aciclovir may cause local skin reactions.

Common Side Effects

• Mild burning or stinging at the application site.
• Itching or mild irritation.
• Redness or erythema.
• Dryness or peeling of the skin.
• Tingling sensation.
• Minor rash.

Serious or Rare Side Effects

• Allergic contact dermatitis.
• Severe skin rash or exfoliative dermatitis.
• Swelling of the face, lips, or tongue.
• Blistering or ulceration of the treated area.
• Anaphylactic reaction (rare).
• Persistent or worsening irritation requiring medical attention.

When using Koortslipcrème Aciclovir Albert Heijn, follow these safety measures.

• Apply only to intact skin: avoid broken skin or mucous membranes.
• Do not use near the eyes: keep the product away from ocular surfaces.
• Use with caution in infants under 12 months unless directed by a healthcare professional.
• Consult a healthcare professional if you are pregnant or breastfeeding.
• Discontinue use and seek medical advice if severe irritation or allergic reaction occurs.
• Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Topical aciclovir has limited systemic interactions, but certain combinations may affect safety or efficacy.

Major Interactions (Avoid)

• Concurrent use of other topical antiviral agents: may increase local irritation.
• Use with systemic immunosuppressants: may reduce antiviral efficacy.
• Application of multiple topical medications on the same area: risk of additive skin irritation.

Moderate Interactions (Monitor Closely)

• Co‑application with topical corticosteroids: may mask signs of infection.
• Use with skin sensitizers or fragrances: monitor for heightened irritation.
• Combination with over‑the‑counter skin products (e.g., moisturizers, acne treatments): assess compatibility and watch for adverse skin reactions.