Product image of Koortslipcrème Aciclovir Livsane (Aciclovir) supplied by GNH India

Koortslipcrème Aciclovir Livsane

Active Ingredient:
Aciclovir
Origin:
EU

Koortslipcrème Aciclovir Livsane (Aciclovir)

Aciclovir, the active ingredient in Koortslipcrème Aciclovir Livsane, is an antiviral presented as a cream for topical use. It treats herpes labialis (cold sores) and other localized herpes simplex infections in adults and children.

GNH India supplies Koortslipcrème Aciclovir Livsane as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Healthypharm B.V.

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Indications & Clinical Uses

  • Aciclovir is an antiviral that acts on herpes simplex virus infections.
  • Herpes labialis: reduces lesion duration, pain and viral shedding.
  • Localized herpes simplex infection: limits viral replication and promotes lesion healing.
  • Recurrent cold sores: helps control outbreak frequency and severity.

How It Works

  • Aciclovir is a nucleoside analogue that is phosphorylated by viral thymidine kinase and subsequently converted to aciclovir triphosphate. This active metabolite competitively inhibits viral DNA polymerase, blocking viral DNA chain elongation and preventing replication of herpes simplex virus in infected cells.

Side Effects

Topical aciclovir may cause local skin reactions.

Common Side Effects

  • Mild burning or stinging at the application site
  • Transient itching or tingling sensation
  • Redness or mild erythema
  • Dryness or peeling of the treated skin

Serious or Rare Side Effects

  • Severe allergic reaction such as angioedema or anaphylaxis
  • Contact dermatitis with extensive rash
  • Erythema multiforme or Stevens‑Johnson‑like reactions
  • Skin ulceration or necrosis at the site of application

Precautions & Warnings

Use aciclovir cream with awareness of specific safety considerations.

  • Pregnancy: consult a healthcare professional before use.
  • Breastfeeding: discuss potential risks with a doctor.
  • Age: use with caution in children under 12 years.
  • Allergy: avoid if known hypersensitivity to aciclovir or excipients.
  • Application: apply only to intact lesions, avoid eyes, mucous membranes and broken skin.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Aciclovir cream may interact with other topical or systemic agents.

Major Interactions (Avoid)

  • Concurrent systemic aciclovir: may increase overall exposure.
  • Topical immunosuppressants: can reduce antiviral efficacy.

Moderate Interactions (Monitor Closely)

  • Topical corticosteroids: may mask local irritation.
  • Other antiviral creams: overlapping toxicity potential.
  • Herbal or cosmetic skin products: possible irritation or reduced absorption.

Frequently Asked Questions

Koortslipcrème Aciclovir Livsane is a topical cream containing aciclovir that is used to treat herpes labialis (cold sores) and other localized herpes simplex infections by reducing lesion duration and discomfort.

Aciclovir is converted inside infected cells to a triphosphate form that inhibits viral DNA polymerase, preventing the herpes simplex virus from replicating its DNA and thereby limiting the spread of infection.

The dosage and frequency are determined by the prescribing healthcare professional based on the severity of the lesions and patient characteristics. The prescriber will provide specific application instructions.

Safety in pregnancy and lactation has not been fully established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.

Enquiries can be submitted on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Aciclovir cream offers a direct topical approach, delivering the antiviral agent to the lesion site, whereas oral antivirals provide systemic exposure. Compared with other topical agents such as penciclovir, aciclovir has a similar efficacy profile but may differ in formulation and tolerability.

Store the cream at room temperature, preferably below 25 °C. Keep it in the original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use.

Apply a thin layer of the cream to the affected area, typically five times daily, or as directed by the prescriber. Wash hands before and after application, and avoid contact with eyes, mouth and other mucous membranes.

Serious risks include severe allergic reactions such as angioedema or anaphylaxis, extensive contact dermatitis, and rare severe skin reactions like erythema multiforme. Patients should seek immediate medical attention if they experience swelling, difficulty breathing, or widespread rash.

Individuals with a known hypersensitivity to aciclovir or any component of the cream should avoid its use. It is also contraindicated on broken skin, mucous membranes, or in patients where a prescriber determines the risks outweigh the benefits.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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