ACTILYSE 20MG INFUSION - Alteplase(20mg)

Storage/Handling:

Store below 30°C

Uses of ACTILYSE 20MG INFUSION - Alteplase(20mg):

This medication is used in the treatment of the problems-
Treatment of Heart attack
Treatment of Ischemic stroke
Treatment of Pulmonary embolism

Product Introduction:

Actilyse 20 mg Injection is a thrombolytic agent formulated for dissolving blood clots. It is indicated for the treatment of stroke, pulmonary embolism, and prevention of heart attack. By breaking down the clot, it helps restore blood flow to the affected area.

ACTILYSE 20MG INJECTION is used for the lysis of blood clots to restore blood flow in the affected tissues or organs. It is used for the treatment of Acute Massive Pulmonary Embolism (PE) and Acute Ischemic Stroke (AIS). ACTILYSE 20MG INJECTION contains alteplase, which works by dissolving the blood clots that block the flow of blood to the affected tissue, thereby restoring blood flow and effectively treating various medical conditions. It has been proven to be an effective treatment option for both Acute Massive Pulmonary Embolism (PE) and Acute Ischemic Stroke (AIS). In both conditions, ACTILYSE 20MG INJECTION can be used for the lysis of blocked blood clots to restore normal blood flow in the affected tissue or organ.

Actilyse 20mg Injection is given directly into a vein by a doctor as soon as possible after the first signs of a heart attack, stroke, or pulmonary embolism are noticed. Your breathing, blood pressure, oxygen levels and other vital signs will be watched closely. You may be given another medicine to prevent the formation of new blood clots at the same time or after the treatment.

It should not be used in patients who have had genetic bleeding disorders, neoplasms (tumours), or any other cerebrovascular accident (a stroke or similar attack affecting the brain, often due to a clot or bleeding in a blood vessel in the brain) as it could cause the patient’s condition to worsen.

There are various reasons why Actilyse 20mg Injection is not used for everyone. Actilyse 20mg Injection should not be administered to those with a history of head injury, surgery involving the brain or spine, or any present bleeding. Your healthcare provider must be informed of your complete medical record before this medicine can be administered.

Benefits of ACTILYSE 20MG INFUSION - Alteplase(20mg):

Actilyse 20mg Injection is used to treat a range of cardiovascular conditions, such as heart attack, ischemic stroke, and pulmonary embolism. It works by dissolving harmful blood clots that form in other blood vessels and that can lead to these conditions by reducing the damage caused and the risk of death. For Pulmonary embolism Actilyse 20mg Injection prevents this clot formation in your lungs. This helps the blood flow freely around your body thereby preventing a heart attack or stroke. Actilyse 20mg Injection should be administered as soon as possible following the onset of these conditions to maximize the chances of recovery. Lifestyle changes, such as eating a healthy diet and staying active, may also increase the effectiveness of this medication. It is important to follow your doctor’s instructions carefully to get the best outcomes.

Side Effects of ACTILYSE 20MG INFUSION - Alteplase(20mg):

These are the major & minor side effects for Actilyse 20 mg Injection are -
1. Difficulty in breathing
2. Nosebleed
3. Vomiting
4. Increased menstrual flow
5. Dizziness
6. Headache
7. Nausea
8. Black or Tarry stools
9. Bleeding gums

Drug Interactions:

Drug-Drug Interactions: The medication shows severe reaction with the following-
Enoxaparin
Apixaban
Warfarin
Abciximab
It is advisable to consult your doctor about all the possible interactions of the drugs you’re taking.
Drug-Food Interactions: No information is available
Drug-Disease Interactions: This medicine is not recommended for use in patients with bleeding disorders. Consult your doctor and inform regarding all kind of health problems you have before taking the medication.

How ACTILYSE 20MG INFUSION - Alteplase(20mg) Works:

Actilyse 20mg Injection is a thrombolytic medication which help eliminate harmful blood clots in the blood vessels. This allows blood to resume flowing to affected tissues, thus preventing tissue death and improving outcomes.

How To Use ACTILYSE 20MG INFUSION - Alteplase(20mg):

The injection will be administered by a healthcare professional. Do not self-administer.

Safety Instructions For ACTILYSE 20MG INFUSION - Alteplase(20mg):

PREGNANCY Consult your Doctor If you are pregnant, Actilyse 20mg Injection may pose a risk to your unborn baby's health. Animal studies have revealed potential harm to the fetus, although the effects of this medication on humans are unknown. Before prescribing this drug to you, your doctor will review your personal situation and consider any potential risks. It is important that you consult with your doctor before taking this medication. ALCOHOL Consult your Doctor It is unclear if it is safe to consume alcohol while taking Actilyse 20mg Injection, so please consult your doctor for advice. BREAST FEEDING Safe If Prescribed While there is limited human data, Actilyse 20mg Injection is likely to be safe for use during breastfeeding. The drug does not appear to carry a significant risk of harming the baby. LIVER Consult your Doctor There is limited information available on the use of Actilyse 20mg Injection in patients with liver disease. Please consult your doctor. KIDNEY Safe If Prescribed It is likely that Actilyse 20mg Injection is safe to use in patients with kidney disease. The available information suggests that no adjustment of dosage is necessary in these patients; however, it is recommended to consult a physician for more information. Driving Not Relevant Not relevant, as Actilyse 20mg Injection is intended for use in hospitalised patients.

Habit Forming

No

Remember:

# In the event of an allergic reaction, the infusion should be discontinued and appropriate treatment should be initiated immediately. Seek medical help as soon as possible in case of any signs of an allergic reaction or other serious side effects such as difficulty breathing, hives, or swelling of the face, tongue, or throat.
# Due to limited evidence on the safety and efficacy of using this medicine in children under 16 years of age, it is strongly recommended to be administered only under the supervision of a medical professional. If the potential benefits are deemed to outweigh risks, then the patient must be carefully monitored for any side effects.
# Signs that should be reported to your doctor right away are nosebleeds, gum bleeding, black or dark-colored stools, or unexplained bruising.
# Further, this medication should be administered as soon as possible, within 12 hours for heart attack and 4.5 hours for stroke, as indicated.
# Additionally, medicines that were prescribed prior to the injection should not be discontinued as it increases the risk of having a second heart attack or stroke.

FAQs:

1. How does Actilyse 20mg Injection work?

Actilyse 20mg Injection contains Alteplase, which works by breaking down and dissolving the clot blocking the artery. This helps to restore the blood flow to the affected area, treating medical conditions caused by blocked arteries, such as stroke or heart attack.

2. How is Actilyse 20mg Injection administered?

Actilyse 20mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get the maximum benefit from Actilyse 20mg Injection.

3. What are the instructions for the storage and disposal of Actilyse 20mg Infusion?

Store this medication in its original packaging in a cool, dry place and ensure that it is kept out of the reach of both children and pets.

4. Is Actilyse 20mg Injection safe?

Actilyse 20mg Injection should be taken as prescribed by your doctor. Ensure you follow the instructions carefully and take it exactly as directed. Do not change or adjust the dosage in any way without consulting your doctor first. Let your doctor know if you experience any side effects. It is recommended to take this medication safely and appropriately in order to avoid any unpleasant or dangerous reactions.

5. When will I feel better after taking Actilyse 20mg Injection?

Taking Actilyse 20mg Injection can help lower your risk of forming blood clots in the blood vessels around your leg, lungs, heart and brain. You may not feel any changes after taking this medication, but that doesn’t mean it is not working. Make sure you continue to take Actilyse 20mg Injection as your doctor has prescribed.

6. Can taking Actilyse 20mg Injection increase the risk of bleeding?

If you experience any bleeding related to this therapy, it is usually temporary and should resolve on its own. However, if the bleeding persists, make sure to contact your doctor.