Product image of Alfinor (Betahistine Dihydrochloride) supplied by GNH India

Alfinor

Active Ingredient:
Betahistine Dihydrochloride
Origin:
EU

Alfinor (Betahistine Dihydrochloride)

Betahistine Dihydrochloride, the active ingredient in Alfinor, is a histamine H1 receptor agonist and H3 antagonist presented as a 24 mg oral tablet for systemic use. It is used to manage symptoms associated with Ménière's disease, vertigo, and other vestibular disorders in adults.

GNH India supplies Alfinor as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Manufacturer / TM Owner

Medochemie Ltd.

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Indications & Clinical Uses

Alfinor is indicated for the treatment of vestibular disorders, primarily targeting symptoms associated with Ménière's disease and vertigo. It helps to alleviate symptoms such as:

  • Ménière's disease: Reduces the frequency and severity of vertigo attacks, tinnitus, and hearing loss.
  • Vertigo: Improves balance and reduces episodes of dizziness.
  • Balance disorders: Enhances stability and coordination in individuals with vestibular dysfunction.

How It Works

  • Betahistine Dihydrochloride acts as a histamine H1 receptor agonist and H3 antagonist. It increases histamine turnover and improves microcirculation in the inner ear, thereby reducing endolymphatic pressure and alleviating vertigo. This mechanism helps to stabilize vestibular function and reduce symptoms associated with vestibular disorders.

Side Effects

Alfinor may cause several side effects, ranging from mild to severe. Common side effects include:

Common Side Effects

  • Nausea: Mild stomach discomfort or vomiting.
  • Headache: Mild to moderate headache.
  • Dizziness: Temporary feelings of lightheadedness.
  • Digestive issues: Mild gastrointestinal disturbances.

Serious or Rare Side Effects

  • Allergic reactions: Rare but possible, including skin rash or itching.
  • Severe dizziness: Persistent or severe vertigo.
  • Gastrointestinal bleeding: Rare but serious, requiring immediate medical attention.

Precautions & Warnings

Alfinor should be used with caution in certain populations and conditions. Key precautions include:

  • Pregnancy: Consult a healthcare provider before use during pregnancy.
  • Breastfeeding: Use with caution and under medical supervision.
  • Asthma: Monitor closely for respiratory effects.
  • Peptic ulcers: Use with caution due to potential gastrointestinal effects.
  • Allergies: Avoid if allergic to betahistine or any excipients.
  • Store below 25°C: Keep in the original pack, protect from moisture.

Avoid Interactions

Alfinor may interact with other medications, potentially affecting its efficacy or safety. Major and moderate interactions include:

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): Avoid concurrent use due to potential severe interactions.
  • Antihistamines: May reduce the effectiveness of Alfinor.

Moderate Interactions (Monitor Closely)

  • Anticholinergics: May exacerbate side effects such as dry mouth and constipation.
  • Sedatives: May enhance drowsiness and dizziness.
  • Antidepressants: Monitor for increased side effects.

Frequently Asked Questions

Alfinor is used to manage symptoms associated with Ménière's disease, vertigo, and other vestibular disorders. It helps to reduce the frequency and severity of vertigo attacks, tinnitus, and hearing loss, as well as improve balance and coordination.

Betahistine Dihydrochloride acts as a histamine H1 receptor agonist and H3 antagonist. It increases histamine turnover and improves microcirculation in the inner ear, thereby reducing endolymphatic pressure and alleviating vertigo. This mechanism helps to stabilize vestibular function and reduce symptoms associated with vestibular disorders.

The usual dose of Alfinor is determined by a healthcare provider based on the individual's condition and response to treatment. It is typically taken in divided doses throughout the day, with or without food. Always follow the prescribed dosage and instructions provided by your healthcare professional.

The safety of Alfinor during pregnancy or breastfeeding has not been fully established. It is important to consult a healthcare provider before using Alfinor if you are pregnant, planning to become pregnant, or breastfeeding. Your healthcare provider can assess the potential benefits and risks and provide appropriate guidance.

To order Alfinor from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will reply with pricing, availability, shipping, and the necessary import paperwork.

Alfinor is a histamine H1 receptor agonist and H3 antagonist, which differentiates it from other anti-vertigo medications that may act through different mechanisms. It is specifically indicated for Ménière's disease and vestibular disorders. The choice of medication depends on the individual's condition, response to treatment, and healthcare provider's recommendation.

Alfinor should be stored below 25°C, in the original pack, and protected from moisture. Keep the medication out of reach of children and follow the storage instructions provided on the packaging. Proper storage ensures the effectiveness and safety of the medication.

Alfinor is administered orally, typically in divided doses throughout the day. It can be taken with or without food, as directed by a healthcare provider. Always follow the prescribed dosage and instructions provided by your healthcare professional.

The most serious risks associated with Alfinor include severe allergic reactions, persistent or severe vertigo, and gastrointestinal bleeding. If you experience any of these symptoms, seek immediate medical attention. Always inform your healthcare provider of any adverse effects.

Alfinor should not be used by individuals who are allergic to betahistine or any of its excipients. It should also be used with caution in individuals with asthma, peptic ulcers, or during pregnancy and breastfeeding. Always consult a healthcare provider before starting Alfinor to ensure it is safe for you.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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