Product image of Актилизе (Alteplase) 20 mg Powder and solvent for solution for injection and infusion supplied by GNH India

Актилизе

Active Ingredient:
Alteplase
Form:
Powder and solvent for solution for injection and infusion
Origin:
EU

Актилизе (Alteplase Powder and solvent for solution for injection and infusion) 20 mg

Актилизе (alteplase) is a thrombolytic medication used to dissolve blood clots in emergency settings. This prescription-only treatment helps restore blood flow in conditions like stroke or heart attack. It works by activating plasminogen to break down fibrin in clots. Short-term use under medical supervision is typical.

Strength

20 mg

Manufacturer / TM Owner

Boehringer Ingelheim International Gmbh

1
Pack/s
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Indications & Clinical Uses

  • Актилизе (alteplase) is used in emergency medicine to treat conditions caused by blood clots, such as acute ischemic stroke, myocardial infarction, or pulmonary embolism. It may also be used to clear clots in central venous catheters. The medication helps restore blood flow by dissolving fibrin clots. It is administered in a controlled clinical environment.

Side Effects

  • When administered, alteplase works by converting plasminogen into plasmin, which then breaks down fibrin in blood clots. This process helps restore normal blood flow in affected areas. Patients may experience improved symptoms related to clot-related conditions, though individual responses vary. Effects are typically monitored closely during and after administration.

Precautions & Warnings

  • Alteplase should only be handled and administered by healthcare professionals in a clinical setting. It requires careful patient selection to avoid risks like bleeding complications. Storage should follow manufacturer guidelines to maintain potency. Patients with a history of bleeding disorders or recent surgery may need special consideration.

Avoid Interactions

  • Alteplase may interact with medications that affect blood clotting, such as anticoagulants or antiplatelets. Combining it with other thrombolytics or certain herbal supplements could increase bleeding risk. Alcohol and certain pain relievers may also pose additional risks. Always inform healthcare providers about all medications being taken.

Frequently Asked Questions

Alteplase is used to dissolve blood clots in emergency conditions like stroke, heart attack, or pulmonary embolism.

Alteplase is given as an intravenous infusion in a hospital or clinical setting under medical supervision.

No, alteplase requires administration by trained healthcare professionals in a controlled environment.

Common effects may include bleeding or bruising at the injection site, though these are monitored closely.

No, it is not suitable for patients with active bleeding, recent surgery, or certain medical conditions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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