Product image of Alyr (Cetirizine Dihydrochloride) supplied by GNH India

Alyr

Active Ingredient:
Cetirizine Dihydrochloride
Origin:
EU

Alyr (Cetirizine Dihydrochloride)

Cetirizine dihydrochloride, the active ingredient in Alyr, is a second-generation H1 antihistamine presented as a 10 mg film-coated tablet for oral use. It is indicated for the relief of symptoms associated with allergic rhinitis and chronic idiopathic urticaria in adults and children aged 6 years and older.

GNH India supplies Alyr as a licensed, GDP-compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bausch Health Ireland Limited

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Indications & Clinical Uses

Alyr is an antiallergic medication used to manage symptoms of allergic reactions. It is primarily indicated for the following conditions:

  • Allergic rhinitis: Relieves symptoms such as sneezing, itchy and watery eyes, and nasal congestion.
  • Chronic idiopathic urticaria: Reduces the occurrence and severity of hives and itching.
  • Seasonal allergic rhinitis: Alleviates symptoms during specific times of the year when allergens are prevalent.

How It Works

  • Alyr works by selectively blocking peripheral H1-receptors, which prevents histamine from binding to these receptors. This action inhibits histamine-induced symptoms such as itching, swelling, and vasodilation, thereby providing relief from allergic reactions.

Side Effects

Alyr may cause various side effects, ranging from common to serious or rare. Common Side Effects:

  • Somnolence (sleepiness)
  • Fatigue
  • Dry mouth
  • Headache
  • Pharyngitis (sore throat)
  • Gastrointestinal disturbances

Serious or Rare Side Effects

  • Dizziness
  • Tachycardia (rapid heart rate)
  • Hepatic dysfunction (liver problems)
  • Angioedema (severe allergic reaction)
  • Anaphylaxis (life-threatening allergic reaction)

Precautions & Warnings

Alyr should be used with caution in certain populations and conditions. Consult a healthcare professional before use if:

  • Allergy to cetirizine or any of the excipients: Avoid use if allergic to cetirizine or related compounds.
  • Renal impairment: Dose adjustment may be necessary for patients with severe kidney disease.
  • Elderly patients: May be more sensitive to the effects of the medication.
  • Pregnancy and breastfeeding: Safety has not been established; consult a doctor before use.
  • Concomitant use with alcohol or other CNS depressants: May enhance sedative effects.
  • Store below 25°C: Keep in the original pack, protect from moisture.

Avoid Interactions

Alyr may interact with other medications, leading to potential adverse effects. Major Interactions (Avoid):

  • Alcohol: May increase sedative effects.
  • CNS depressants: May enhance drowsiness and impair cognitive function.

Moderate Interactions (Monitor Closely)

  • Theophylline: May reduce the effectiveness of cetirizine.
  • Anticholinergic drugs: May increase the risk of anticholinergic effects such as dry mouth and constipation.
  • Sedating antihistamines: May enhance sedative effects.

Frequently Asked Questions

Alyr is used to relieve symptoms of allergic rhinitis and chronic idiopathic urticaria. It helps manage symptoms such as sneezing, itchy and watery eyes, nasal congestion, and hives.

Cetirizine, the active ingredient in Alyr, works by blocking peripheral H1-receptors. This prevents histamine from binding to these receptors, thereby reducing symptoms like itching, swelling, and vasodilation.

The usual dose of Alyr is determined by a healthcare professional based on the patient's age, condition, and response to treatment. Always follow the prescribed dosage.

The safety of Alyr during pregnancy and breastfeeding has not been established. Consult a healthcare professional before use if you are pregnant or breastfeeding.

To order Alyr from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask you to confirm your trade or institutional credentials. The team will then provide pricing, availability, shipping details, and the necessary import paperwork.

Alyr is a second-generation antihistamine, which means it is less likely to cause sedation compared to first-generation antihistamines. It is specifically formulated to provide relief from allergic symptoms with minimal drowsiness.

Alyr should be stored below 25°C, kept in the original pack, and protected from moisture. Ensure the medication is stored in a cool, dry place away from direct sunlight and out of reach of children.

Alyr is administered orally, typically as a 10 mg film-coated tablet. The tablet can be taken with or without food, as directed by a healthcare professional.

The most serious risks associated with Alyr include angioedema and anaphylaxis, which are severe allergic reactions. If you experience symptoms such as swelling of the face, lips, or throat, difficulty breathing, or severe dizziness, seek immediate medical attention.

Alyr should not be used by individuals who are allergic to cetirizine or any of the excipients in the medication. Patients with severe renal impairment should use it with caution and under medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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