Amiodarone 150mg - VULCAN (Amiodarone) 150 mg

Amiodarone 150mg - VULCAN is a prescription cardiovascular medication containing the active ingredient amiodarone, a Class III antiarrhythmic agent. It is formulated to help manage and stabilize severe, life-threatening disturbances in heart rhythm. By regulating electrical signals in the heart, this medication assists in restoring a normal cardiac rhythm.

Strength

150 mg

Storage

Ambient

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Indications & Clinical Uses

Amiodarone 150mg - VULCAN is primarily indicated for the treatment and prevention of documented, life-threatening ventricular arrhythmias. This includes recurrent ventricular fibrillation and hemodynamically unstable ventricular tachycardia in patients who have not responded to other antiarrhythmic therapies.

Side Effects

Common side effects of amiodarone may include nausea, vomiting, fatigue, tremors, and increased sensitivity to sunlight. Serious adverse effects can occur, including pulmonary toxicity, hepatic dysfunction, thyroid abnormalities (both hyperthyroidism and hypothyroidism), ophthalmic microdeposits, and the potential worsening of cardiac arrhythmias.

Precautions & Warnings

This medication is classified under Pregnancy Category D, indicating potential risks to the fetus, and should only be used if the clinical benefit outweighs the potential risk. Patients with pre-existing thyroid disease, liver impairment, or specific cardiac conduction disorders like severe sinoatrial node dysfunction or AV block should use this drug with extreme caution. Regular monitoring of pulmonary, hepatic, thyroid, and ophthalmic functions is highly recommended.

Avoid Interactions

Amiodarone 150mg - VULCAN has a high potential for drug interactions due to its extensive metabolism and effects on cardiac conduction. It can interact significantly with other antiarrhythmics, beta-blockers, calcium channel blockers, oral anticoagulants like warfarin, and medications that prolong the QT interval. Patients should avoid consuming grapefruit or grapefruit juice, as it can increase amiodarone levels in the blood.

Frequently Asked Questions

Amiodarone 150mg VULCAN is a prescription medication used to treat and prevent life-threatening ventricular arrhythmias, such as recurrent ventricular fibrillation and unstable ventricular tachycardia, when other treatments are ineffective or not tolerated.

As a Class III antiarrhythmic, it primarily works by blocking potassium channels to prolong the phase 3 action potential of cardiac cells. It also exhibits sodium, beta-adrenergic, and calcium channel blocking properties to help stabilize irregular heart rhythms.

Serious risks include pulmonary toxicity (lung damage), liver injury, thyroid dysfunction (hypothyroidism or hyperthyroidism), vision changes, and the potential to worsen existing heart arrhythmias. Regular clinical monitoring is required to detect these issues early.

Amiodarone is classified as Pregnancy Category D, meaning there is evidence of potential risk to the human fetus. It should only be used during pregnancy in life-threatening situations where no safer alternative treatment is available.

Yes, patients taking this medication must avoid consuming grapefruit and grapefruit juice, as it can interfere with the drug's metabolism, leading to increased levels of amiodarone in the body and a higher risk of side effects.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 17 Jun 2026

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