Product image of Avlocardyl (Propranolol Hydrochloride) supplied by GNH India

Avlocardyl

Active Ingredient:
Propranolol Hydrochloride
Origin:
EU

Avlocardyl (Propranolol Hydrochloride)

Propranolol, the active ingredient in Avlocardyl, is a beta-blocker presented as a 40 mg tablet for oral use. It is used to treat conditions such as hypertension, angina pectoris, and certain cardiac arrhythmias, as well as for migraine prophylaxis and essential tremor. GNH India supplies Avlocardyl as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

Avlocardyl is a well-established medication known for its efficacy in managing various cardiovascular and neurological conditions. It is widely prescribed due to its proven benefits and safety profile when used as directed.

Manufacturer / TM Owner

Atnahs Pharma Netherlands B.V.

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Indications & Clinical Uses

Avlocardyl is a beta-blocker used to manage various cardiovascular and neurological conditions. It acts on the beta-adrenergic receptors to provide therapeutic effects.

  • Hypertension: Reduces blood pressure by decreasing heart rate and myocardial contractility.
  • Angina pectoris: Improves blood flow to the heart, reducing chest pain.
  • Myocardial infarction prophylaxis: Helps prevent subsequent heart attacks in patients with a history of myocardial infarction.
  • Cardiac arrhythmias: Manages abnormal heart rhythms by regulating heart rate and contractility.
  • Migraine prophylaxis: Reduces the frequency and severity of migraine headaches.
  • Essential tremor: Helps control tremors by blocking beta-adrenergic receptors in the brain.

How It Works

  • Avlocardyl works by blocking beta-adrenergic receptors in the heart and blood vessels. This action reduces heart rate, myocardial contractility, and renin release, leading to decreased blood pressure and improved blood flow. By inhibiting the effects of adrenaline and noradrenaline, it helps manage conditions such as hypertension, angina, and arrhythmias, as well as migraines and tremors.

Side Effects

Avlocardyl, like other medications, can cause side effects, although not everyone experiences them. Common Side Effects:

  • Fatigue: Feeling tired or weak.
  • Dizziness: Lightheadedness or vertigo.
  • Nausea: Feeling sick to the stomach.
  • Cold extremities: Hands and feet may feel cold.
  • Bradycardia: Slower than normal heart rate.
  • Diarrhea: Loose or watery stools.

Serious or Rare Side Effects

  • Bronchospasm: Difficulty breathing, especially in patients with asthma.
  • Heart block: Severe slowing or irregular heartbeat.
  • Hypotension: Abnormally low blood pressure.
  • Depression: Mood changes or depressive symptoms.
  • Allergic reactions: Rash, itching, or swelling.

Precautions & Warnings

Avlocardyl should be used with caution and under medical supervision. Certain conditions and interactions may require dose adjustments or avoidance of the medication. Actions:

  • Asthma: Avoid use in patients with asthma due to the risk of bronchospasm.
  • Heart block: Caution in patients with second- or third-degree heart block.
  • Diabetes: May mask symptoms of hypoglycemia.
  • Pregnancy: Use only if clearly needed; consult a healthcare provider.
  • Breastfeeding: Use with caution; consult a healthcare provider.
  • Store below 25°C: Keep in the original pack, protect from moisture.

Avoid Interactions

Avlocardyl can interact with other medications, potentially altering its effectiveness or increasing the risk of side effects. Major Interactions (Avoid):

  • Verapamil: Can cause severe bradycardia or heart block.
  • Diltiazem: May increase the risk of heart block.
  • Insulin: May mask symptoms of hypoglycemia.
  • MAO inhibitors: Can cause severe hypotension.
  • Non-dihydropyridine calcium channel blockers: May increase the risk of heart block.

Moderate Interactions (Monitor Closely)

  • Digoxin: May increase the risk of bradycardia.
  • Clonidine: May cause severe hypertension if discontinued abruptly.
  • Antiarrhythmic drugs: May increase the risk of bradycardia or heart block.
  • Antidepressants: May increase the risk of depression or mood changes.

Frequently Asked Questions

Avlocardyl is used to treat hypertension, angina pectoris, certain cardiac arrhythmias, and for migraine prophylaxis. It is also effective in managing essential tremors by blocking beta-adrenergic receptors, which helps regulate heart rate and blood pressure.

Propranolol, the active ingredient in Avlocardyl, works by blocking beta-adrenergic receptors in the heart and blood vessels. This action reduces heart rate, myocardial contractility, and renin release, leading to decreased blood pressure and improved blood flow.

The usual dose of Avlocardyl varies depending on the condition being treated and is determined by a healthcare provider. It is typically started at a low dose and adjusted based on the patient's response and tolerance.

The safety of Avlocardyl during pregnancy has not been established. It should be used during pregnancy only if clearly needed and under the supervision of a healthcare provider. Consult your doctor for personalized advice.

To order Avlocardyl from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will reply with pricing, availability, shipping, and the import paperwork.

Avlocardyl, containing Propranolol, is a non-selective beta-blocker. It is similar to other beta-blockers in its mechanism of action but may have different side effect profiles and indications. Consult your healthcare provider to determine the most suitable beta-blocker for your condition.

Avlocardyl should be stored below 25°C, in the original pack, and protected from moisture. Keep it out of reach of children and pets. Always follow the storage instructions provided on the packaging or by your healthcare provider.

Avlocardyl is administered orally, typically in the form of tablets. The dosage and frequency are determined by a healthcare provider based on the patient's condition and response to the medication. Always follow the prescribed dosage and instructions.

The most serious risks of Avlocardyl include bronchospasm, heart block, hypotension, and severe bradycardia. It can also cause depression and allergic reactions. Patients should be monitored closely for these potential side effects, and any severe reactions should be reported to a healthcare provider immediately.

Avlocardyl should not be used by patients with asthma, severe bradycardia, heart block, or those who are hypersensitive to Propranolol. It should be used with caution in patients with diabetes, liver disease, or peripheral vascular disease. Always consult a healthcare provider before starting Avlocardyl.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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