Product image of Orofar Lidocaïne Parels (Benzoxonium Chloride, Lidocaine Hydrochloride) supplied by GNH India

Orofar Lidocaïne Parels

Active Ingredient:
Benzoxonium Chloride, Lidocaine Hydrochloride
Origin:
EU

Orofar Lidocaïne Parels (Benzoxonium Chloride, Lidocaine Hydrochloride)

Benzoxonium chloride and lidocaine hydrochloride, the active ingredients in Orofar Lidocaïne Parels, are a local anesthetic and antiseptic presented as an oral formulation for mouth administration. They provide temporary numbness and antimicrobial protection for minor oral procedures in both adults and children, improving comfort during treatment.

GNH India supplies Orofar Lidocaïne Parels as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable distribution across multiple regions globally.

Manufacturer / TM Owner

Eurogenerics N.V./S.A.

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Indications & Clinical Uses

Orofar Lidocaïne Parels, a combined local anesthetic and antiseptic, is used to manage oral discomfort and prevent infection in minor mucosal conditions.

  • Oral mucosal irritation: provides temporary numbing and reduces microbial load
  • Dental procedures (e.g., scaling, minor extractions): alleviates pain during the intervention
  • Oral ulcerations (e.g., aphthous ulcers): eases discomfort and helps prevent secondary infection

How It Works

  • Lidocaine hydrochloride blocks voltage‑gated sodium channels on peripheral nerves, preventing depolarisation and halting impulse transmission, which produces local anaesthesia. Benzoxonium chloride interacts with microbial cell membranes, disrupting their integrity and leading to rapid antimicrobial activity. The combined actions result in temporary loss of sensation and reduced risk of infection at the site of application.

Side Effects

Adverse reactions to Orofar Lidocaïne Parels are generally mild, but serious events can occur.

Common Side Effects

  • Mild burning sensation in the mouth
  • Transient taste alteration
  • Mild oral irritation or redness
  • Nausea

Serious or Rare Side Effects

  • Allergic reactions such as angioedema or anaphylaxis
  • Severe mucosal ulceration
  • Systemic lidocaine toxicity (e.g., seizures, cardiac arrhythmia)
  • Persistent numbness beyond the application site

Precautions & Warnings

When using Orofar Lidocaïne Parels, consider the following precautions:

  • Allergy assessment: avoid use in patients with known hypersensitivity to lidocaine or benzoxonium
  • Age considerations: use with caution in children under two years of age
  • Cardiac conditions: contraindicated in patients with severe conduction disorders
  • Concurrent local anesthetics: limit total dose to prevent toxicity
  • Pregnancy and lactation: consult healthcare professional before use
  • Store at room temperature: keep in original container, protect from moisture and light

Avoid Interactions

Potential drug interactions with Orofar Lidocaïne Parels should be reviewed before therapy.

Major Interactions (Avoid)

  • Class I antiarrhythmic agents (e.g., quinidine, procainamide): may increase lidocaine plasma levels and toxicity
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): can raise systemic exposure

Moderate Interactions (Monitor Closely)

  • Other topical anesthetics: additive local anaesthetic effect
  • Beta‑blockers: may enhance cardiovascular depressant effects
  • Monoamine oxidase inhibitors: potential for increased systemic toxicity

Frequently Asked Questions

Orofar Lidocaïne Parels is an oral formulation that combines a local anaesthetic (lidocaine) with an antiseptic (benzoxonium chloride). It is used to provide temporary numbness and reduce microbial contamination during minor oral procedures, such as dental cleanings, extractions, or treatment of mouth ulcers, helping to improve patient comfort and lower infection risk.

Lidocaine hydrochloride blocks voltage‑gated sodium channels on peripheral nerve membranes, preventing the rapid influx of sodium ions that is required for nerve depolarisation. By inhibiting this process, lidocaine stops the transmission of pain signals, producing a reversible loss of sensation in the area where the product is applied.

The appropriate dose of Orofar Lidocaïne Parels is determined by the prescribing healthcare professional based on the specific clinical situation, patient age, and the extent of the oral area to be treated. The product is supplied for professional use, and the prescriber will provide exact instructions on the amount to apply.

Safety data for the combined use of lidocaine and benzoxonium chloride in pregnancy and lactation are limited. Healthcare providers should weigh the potential benefits against any possible risks. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss the use of this product with their physician before treatment.

To order Orofar Lidocaïne Parels, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After the request, the sales team will verify trade or institutional credentials, then respond with pricing, availability, shipping details and any required import documentation.

Compared with single‑agent gels such as benzocaine, Orofar Lidocaïne Parels offers a dual mechanism: lidocaine provides a more potent and longer‑lasting anaesthetic effect, while benzoxonium chloride adds an antiseptic component that helps reduce microbial load. This combination can be advantageous in settings where both pain control and infection prevention are desired.

Store Orofar Lidocaïne Parels at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use to maintain stability and potency.

The product is applied directly to the oral mucosa using a sterile applicator or swab. The prescribed amount is spread evenly over the target area, allowing it to act locally. It is intended for short‑term use under professional supervision, and the patient should avoid swallowing large quantities.

The most serious risks include allergic reactions such as angioedema or anaphylaxis, systemic lidocaine toxicity that can manifest as seizures or cardiac arrhythmias, and severe mucosal ulceration. Patients should be monitored for signs of hypersensitivity or systemic effects, especially when larger amounts are applied or when used in conjunction with other local anaesthetics.

Individuals with a known hypersensitivity to lidocaine, benzoxonium chloride, or any component of the formulation should avoid this product. It is also contraindicated in patients with severe cardiac conduction disorders, those taking Class I antiarrhythmic drugs, and children under two years of age unless specifically directed by a qualified clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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