Orocalm Goût Miel Et Orange (Benzydamine Hydrochloride)

Benzydamine hydrochloride is used for inflammatory conditions of the oral cavity and pharynx, providing symptomatic relief.

• Sore throat: Reduces pain and inflammation in acute pharyngitis.
• Oral mucositis: Alleviates discomfort associated with mucosal ulceration during cancer therapy.
• Post‑operative oral pain: Decreases pain following dental or oral surgery.
• Gingivitis: Helps control mild inflammation and soreness of the gums.
• Minor oral lesions: Provides soothing relief for small traumatic lesions.

• Benzydamine hydrochloride acts locally by inhibiting the synthesis of pro‑inflammatory prostaglandins and cytokines, and by stabilising cell membranes. It also exhibits mild anesthetic properties through sodium‑channel blockade, which together reduce pain and swelling in the oral mucosa without significant systemic absorption.

Benzydamine mouthwash is generally well tolerated, but some patients may experience adverse reactions.

Common Side Effects

• Taste alteration: A transient metallic or bitter taste.
• Oral irritation: Mild burning or stinging sensation at the site of application.
• Dry mouth: Temporary reduction in salivary flow.
• Nausea: Mild queasy feeling after use.

Serious or Rare Side Effects

• Allergic reaction: Rash, itching, swelling, or difficulty breathing.
• Severe mucosal ulceration: Unexpected worsening of oral lesions.
• Angio‑edema: Swelling of lips, tongue or throat requiring urgent care.
• Systemic toxicity: Very rare, signs include dizziness or hypotension.

Before using Benzydamine mouthwash, consider the following safety points.

• Contraindication: Do not use if known hypersensitivity to benzydamine or any formulation excipients.
• Pregnancy: Use only if clearly indicated; limited data suggest caution.
• Breastfeeding: Preferably avoid; benzydamico may be present in milk.
• Pediatric use: Follow prescriber guidance; safety not established for children under 6.
• Drug interactions: Review concomitant oral medications for potential irritation.
• Store at ambient temperature: Keep below 25°C, retain in original packaging and protect from moisture.

Benzydamine hydrochloride may interact with other agents applied to the oral cavity or that affect mucosal integrity.

Major Interactions (Avoid)

• Alcohol‑based mouthwashes: Concurrent use may increase mucosal irritation.
• Strong topical anesthetics: Combined effect may heighten numbness and mask injury.

Moderate Interactions (Monitor Closely)

• Antifungal agents (e.g., nystatin): May alter local absorption.
• Corticients corticosteroids: May affect healing dynamics.
• Systemic NSAIDs: Overlapping anti‑inflammatory actions could increase risk of gastrointestinal irritation.