Product image of Neoseptolete Combi Citron A Zázvor (Benzydamine Hydrochloride, Cetylpyridinium Chloride) supplied by GNH India

Neoseptolete Combi Citron A Zázvor

Active Ingredient:
Benzydamine Hydrochloride, Cetylpyridinium Chloride
Origin:
EU

Neoseptolete Combi Citron A Zázvor (Benzydamine Hydrochloride, Cetylpyridinium Chloride)

Benzydamine hydrochloride, the active ingredient in Neoseptolete Combi Citron A Zázvor, is a non‑steroidal anti‑inflammatory drug presented as an oral preparation for local use in the mouth. It is combined with cetylpyridinium chloride, an antiseptic, to provide relief from sore throat, oral mucositis and mouth ulcer pain in adults and children.

GNH India supplies Neoseptolete Combi Citron A Zázvor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Krka, D.D., Novo Mesto

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Indications & Clinical Uses

Neoseptolete Combi Citron A Zázvor acts locally on inflamed oral mucosa and bacterial colonisation, providing symptomatic relief in several common conditions.

  • Sore throat: reduces pain and inflammation of the pharyngeal mucosa.
  • Oral mucositis: alleviates discomfort associated with chemotherapy or radiotherapy‑induced mucosal injury.
  • Mouth ulcer pain: eases burning and irritation of aphthous lesions.

How It Works

  • Benzydamine hydrochloride inhibits pro‑inflammatory cytokine release and stabilises cell membranes, producing local anti‑inflammatory, analgesic and mild anaesthetic effects. Cetylpyridinium chloride, a cationic surfactant, disrupts bacterial cell membranes, delivering broad‑spectrum antiseptic activity that reduces microbial load on the oral mucosa.

Side Effects

Neoseptolete Combi Citron A Zázvor is generally well tolerated when used as directed.

Common Side Effects

  • Transient oral burning or tingling sensation.
  • Mild taste alteration.
  • Temporary dry mouth.
  • Minor irritation of the oral mucosa.

Serious or Rare Side Effects

  • Allergic reactions such as rash, itching or swelling.
  • Severe oral ulceration or tissue necrosis.
  • Persistent dysphagia.
  • Signs of systemic toxicity (very rare).

Precautions & Warnings

Before using Neoseptolete Combi Citron A Zázvor, consider the following safety measures.

  • Allergies: avoid if known hypersensitivity to benzydamine, cetylpyridinium chloride or any formulation components.
  • Pregnancy: consult a healthcare professional before use; safety data are limited.
  • Breastfeeding: discuss potential risks with a clinician.
  • Children: ensure age‑appropriate use as advised by a prescriber.
  • Concomitant oral lesions: monitor for worsening irritation.
  • Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture and direct sunlight.

Avoid Interactions

Neoseptolete Combi Citron A Zázvor may interact with other oral agents or systemic medications.

Major Interactions (Avoid)

  • Concurrent use of other topical oral anesthetics may increase local numbness.
  • Co‑administration with strong antiseptic mouthwashes containing chlorhexidine may reduce efficacy.

Moderate Interactions (Monitor Closely)

  • Systemic anti‑inflammatory drugs (e.g., NSAIDs) could augment anti‑inflammatory effects.
  • Anticoagulants: monitor for any unusual oral bleeding.
  • Immunosuppressants: observe for delayed healing of oral lesions.

Frequently Asked Questions

Neoseptolete Combi Citron A Zázvor is indicated for the symptomatic relief of sore throat, oral mucositis and mouth ulcer pain. It works locally in the mouth to reduce inflammation and bacterial colonisation, providing comfort during acute or chronic oral discomfort.

Benzydamine hydrochloride exerts anti‑inflammatory, analgesic and mild anaesthetic effects by inhibiting the release of pro‑inflammatory cytokines and stabilising cell membranes in the oral mucosa. This reduces pain and swelling at the site of application.

The appropriate dose of Neoseptolete Combi Citron A Zázvor is determined by the prescribing healthcare professional based on the patient’s age, condition severity and clinical response. Patients should follow the prescriber’s instructions and the product label.

Safety data for benzydamine hydrochloride and cetylpyridinium chloride in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Neoseptolete combines benzydamine hydrochloride, a locally acting NSAID, with cetylpyridinium chloride, an antiseptic. This dual action offers both anti‑inflammatory relief and antimicrobial activity, which distinguishes it from single‑ingredient products that may only address pain or only provide antiseptic effects.

Store the product at ambient temperature, preferably below 25 °C. Keep it in the original container, protect it from moisture and direct sunlight, and ensure the cap is tightly closed to maintain product stability.

Neoseptolete is intended for oral use. The prescribed amount is applied directly to the affected area of the mouth, such as the throat or ulcer, and may be swished or held briefly before expectorating, following the healthcare professional’s directions.

Serious risks, though rare, include allergic reactions like rash, swelling, or difficulty breathing, and severe oral ulceration or tissue necrosis. Any signs of an allergic response or worsening oral lesions should prompt immediate medical attention.

Individuals with known hypersensitivity to benzydamine hydrochloride, cetylpyridinium chloride, or any excipients in the formulation should avoid using the product. Patients with uncontrolled oral infections or severe mucosal damage should consult a clinician before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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