Bylvay 400 (Odevixibat Capsule) 400mcg

Bylvay 400mcg capsules contain odevixibat, a prescription medication used to treat pruritus in patients with progressive familial intrahepatic cholestasis. This bile acid transport inhibitor helps reduce itching associated with liver conditions. Suitable for adults and children aged 3 months and older.

Strength

400mcg

Pack Size

30s

Storage

Ambient

Manufacturer / TM Owner

Albireo AB

Select Quantity

Pack/s

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Indications & Clinical Uses

Odevixibat, the active ingredient in Bylvay 400mcg, is primarily used to manage pruritus (itching) in individuals with progressive familial intrahepatic cholestasis (PFIC). PFIC is a rare genetic liver disorder that causes bile buildup and severe itching. The medication works by reducing bile acid reabsorption in the intestines, which can alleviate associated symptoms. It is prescribed for patients who have not responded to other treatments.

Side Effects

Bylvay 400mcg capsules may help reduce persistent itching caused by liver-related bile buildup. Users often report a gradual decrease in discomfort over several weeks of consistent use. Some individuals experience improved sleep and daily functioning as itching subsides. The effects vary by patient, and results depend on individual response to the medication.

Precautions & Warnings

Store Bylvay 400mcg capsules at room temperature, away from moisture and direct light. Keep out of reach of children and pets. Do not use if the capsule is damaged or the seal is broken. Always follow your healthcare provider’s instructions for handling and disposal. Report any unusual symptoms to a medical professional promptly.

Avoid Interactions

Bylvay 400mcg may interact with medications that affect bile acid metabolism, such as ursodeoxycholic acid. Combining it with strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) could increase odevixibat levels in the blood. Alcohol and grapefruit products may also influence its effects. Always inform your doctor about all medications and supplements you are taking.

Frequently Asked Questions

Bylvay 400mcg is used to treat severe itching caused by progressive familial intrahepatic cholestasis (PFIC) in adults and children.

It may take several weeks of consistent use to notice a reduction in itching. Individual responses vary.

Yes, Bylvay capsules can be taken with or without food, as directed by a healthcare provider.

Bylvay 400mcg is approved for children aged 3 months and older, but use should be supervised by a doctor.

Take the missed dose as soon as you remember, unless it’s almost time for the next dose. Skip the missed dose if it’s nearly time for the next one.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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