Gluconato De Cálcio B. Braun (Calcium Gluconate)

Gluconato De Cálcio B. Braun is indicated for the correction of calcium deficiency and related conditions. It is commonly employed in clinical settings where rapid restoration of serum calcium is required.

• Treatment of hypocalcemia due to surgical removal of parathyroid glands.
• Management of calcium loss associated with massive blood transfusion.
• Support in patients with severe burns or extensive trauma.
• Adjunct therapy for cardiac arrest when calcium channel blockade is suspected.
• Prevention of tetany in patients receiving citrate‑containing blood products.

Side effects of calcium gluconate injection vary in frequency and severity.

Common

• Local irritation or pain at the injection site.
• Mild nausea or vomiting.
• Transient flushing or warmth sensation.
• Mild headache.
• Temporary increase in serum calcium levels that may cause mild constipation.

Serious

• Hypercalcemia presenting with muscle weakness, arrhythmias, or confusion.
• Severe allergic reaction, including rash, itching, or anaphylaxis.
• Cardiac arrhythmias, especially in patients with underlying heart disease.
• Tissue necrosis if extravasation occurs during intravenous administration.

When using Gluconato De Cálcio B. Braun, several precautions should be observed to ensure safety.

• Assess baseline serum calcium and renal function before administration.
• Use caution in patients with known hypercalcemia, renal impairment, or cardiac disease.
• Monitor cardiac rhythm during rapid intravenous infusion.
• Avoid extravasation; verify proper intravenous line placement.
• Adjust dose in neonates, infants, and elderly patients as needed.
• Discontinue if signs of severe hypercalcemia or allergic reaction develop.

Calcium gluconate can interact with several medications, affecting their efficacy or safety.

Avoid

• Concurrent use with bisphosphonates (e.g., alendronate) without appropriate timing, as calcium may reduce absorption.
• Simultaneous administration with certain antibiotics such as tetracyclines or quinolones, which can form insoluble complexes.

Use with caution

• Loop diuretics (e.g., furosemide) may increase calcium excretion, requiring monitoring.
• Digoxin therapy, as altered calcium levels can affect drug toxicity.
• Vitamin D supplements, which may potentiate hypercalcemia.
• Antacids containing aluminum or magnesium, which can interfere with calcium absorption.