Cardioxane (Dexrazoxane Vials) 500mg

Cardioxane (dexrazoxane) 500mg vials are used to reduce heart damage risk from certain chemotherapy treatments. This cardioprotective agent helps protect heart tissue during doxorubicin-based cancer therapy. Cardioxane injection is indicated for adults receiving specific chemotherapy regimens.

Strength

500mg

Pack Size

Storage

15-25°

Manufacturer / TM Owner

Clinigen Healthcare Ltd.

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Indications & Clinical Uses

Cardioxane is primarily used to reduce the risk of heart damage in patients receiving doxorubicin chemotherapy for cancer. It is indicated for adults who have received a cumulative doxorubicin dose of 300 mg/m² or more and may benefit from continued treatment. The medication helps protect heart muscle cells from the toxic effects of anthracycline chemotherapy. Cardioxane is not a cancer treatment itself but supports heart health during chemotherapy.

Side Effects

Cardioxane works by entering heart cells and binding to iron, which helps prevent oxidative damage caused by chemotherapy drugs like doxorubicin. This protective effect may reduce symptoms such as fatigue, shortness of breath, or swelling that can occur with heart stress during treatment. Patients may notice improved tolerance to chemotherapy sessions when Cardioxane is used as directed.

Precautions & Warnings

Cardioxane should be handled with care and administered by healthcare professionals in a clinical setting. Patients with severe kidney problems may require dose adjustments or closer monitoring. It is important to inform your doctor about all medications and health conditions before starting Cardioxane. Avoid handling broken vials or spilled medication without proper protective equipment.

Avoid Interactions

Cardioxane may interact with other medications that affect bone marrow function or heart rhythm. Drugs such as cyclophosphamide or other cardiotoxic agents should be used cautiously with Cardioxane. Alcohol and certain supplements may also interact, so discuss all current medications with your healthcare provider. No specific food interactions are widely reported, but a balanced diet is recommended during chemotherapy.

Frequently Asked Questions

Cardioxane is used to reduce the risk of heart damage in patients receiving certain chemotherapy drugs like doxorubicin.

Cardioxane is given as an intravenous infusion by a healthcare professional before chemotherapy sessions.

No, Cardioxane is specifically indicated for use with anthracycline chemotherapy like doxorubicin.

Common effects may include fatigue, nausea, or low blood cell counts, which should be monitored by a doctor.

Patients with kidney issues should consult their doctor, as dose adjustments may be necessary.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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