Cephalexin 500 (Cephalexin Capsule) 500mg

Cephalexin 500 is an oral prescription antibiotic capsule containing 500 mg of the active ingredient cephalexin. As a first-generation cephalosporin, it functions as an antibacterial agent by inhibiting bacterial cell wall synthesis. This medication is commonly utilized to treat a range of susceptible bacterial infections in adult and pediatric patients.

Strength

500mg

Pack Size

100s

Storage

Ambient

Select Quantity

Pack/s

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Indications & Clinical Uses

Cephalexin 500 mg capsules are indicated for the treatment of specific infections caused by susceptible strains of microorganisms. Key clinical indications include urinary tract infections (UTIs), respiratory tract infections (such as pharyngitis and tonsillitis), skin and soft tissue infections, otitis media, and osteomyelitis. It is important to note that this antibacterial medication is not effective against viral infections, such as the common cold or influenza.

Side Effects

Common side effects associated with Cephalexin 500 include gastrointestinal symptoms such as diarrhea, nausea, vomiting, dyspepsia, and abdominal pain. Other potential adverse effects include hypersensitivity reactions like skin rashes, urticaria, and localized genital or oral yeast overgrowth. Rare but severe complications can include anaphylaxis and Clostridioides difficile-associated diarrhea (CDAD), which require immediate medical evaluation.

Precautions & Warnings

Before initiating therapy with Cephalexin 500, patients must inform their healthcare provider of any history of hypersensitivity to cephalosporins or penicillins, as cross-reactivity can occur. Caution is warranted in patients with compromised renal function, where dosage adjustments may be necessary. Cephalexin is classified as Pregnancy Category B and should be used during pregnancy or lactation only under direct medical supervision.

Avoid Interactions

Cephalexin 500 can interact with other substances, potentially altering drug clearance or efficacy. Co-administration with probenecid is known to inhibit renal excretion, resulting in elevated and prolonged serum concentrations of cephalexin. Additionally, cephalexin may interact with metformin, potentially increasing metformin exposure, and may reduce the efficacy of certain oral contraceptives.

Frequently Asked Questions

Cephalexin 500 is prescribed to treat a variety of bacterial infections, including urinary tract infections (UTIs), skin and soft tissue infections, respiratory tract infections, middle ear infections (otitis media), and bone infections (osteomyelitis). It is only effective against bacterial pathogens and will not treat viral illnesses.

If you have a history of penicillin allergy, you must consult your healthcare provider before taking Cephalexin 500. While many individuals with mild penicillin allergies can tolerate cephalosporins, there is a risk of cross-sensitivity and potential allergic reactions.

If you miss a dose of Cephalexin 500, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

Cephalexin is classified as Pregnancy Category B, meaning animal studies have not demonstrated a risk to the fetus, but adequate studies in pregnant women are limited. It should be used during pregnancy only when clearly needed and prescribed by a physician.

While alcohol does not directly stop Cephalexin 500 from working, it is generally recommended to avoid alcohol while recovering from an infection. Alcohol can dehydrate the body, affect your immune response, and worsen gastrointestinal side effects like nausea or stomach upset.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 17 Jun 2026

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