Product image of Chemet 100mg (Succimer ) 100mg Capsule supplied by GNH India

Chemet 100mg

Active Ingredient:
Succimer
Form:
Capsule
Brand:
Chemet
Origin:
USA

Chemet 100mg (Succimer Capsule) 100mg

Succimer, the active ingredient in Chemet 100mg, is a chelating agent presented as a 100mg capsule for oral use. It is used to treat lead poisoning in pediatric patients with blood lead levels above 45 µg/dL.

GNH India supplies Chemet 100mg as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Strength

100mg

Pack Size

100s

Storage

15-25°

Manufacturer / TM Owner

Recordati

1
Pack/s
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Indications & Clinical Uses

Chemet 100mg is indicated for the treatment of heavy metal poisoning, primarily lead poisoning.

  • Lead poisoning: Reduces blood lead levels and increases urinary excretion of lead, lowering the risk of severe complications caused by lead poisoning.
  • Mercury poisoning: Limited clinical data suggests increased urinary excretion of mercury and symptomatic improvement.
  • Arsenic poisoning: Limited clinical data suggests increased urinary excretion of arsenic and symptomatic improvement.

How It Works

  • Succimer works by binding to heavy metals such as lead, mercury, and arsenic, forming stable complexes that are excreted in the urine. This process helps to remove these toxic metals from the body, reducing their harmful effects.

Side Effects

Chemet 100mg may cause several side effects, ranging from common to serious.

Common Side Effects

  • Gastrointestinal symptoms, such as nausea, vomiting, and diarrhea.
  • Mild to moderate elevations in serum transaminases.
  • Rashes, which may necessitate discontinuation of therapy.
  • Mild to moderate neutropenia.

Serious or Rare Side Effects

  • Allergic mucocutaneous reactions.
  • Severe gastrointestinal symptoms.
  • Significant elevations in serum transaminases, indicating liver dysfunction.
  • Severe neutropenia, which may require discontinuation of therapy.

Precautions & Warnings

Chemet 100mg should be used with caution and under medical supervision.

  • Hydration: Ensure adequate hydration during therapy.
  • Renal function: Exercise caution in patients with compromised renal function.
  • Liver function: Monitor serum transaminases before and during therapy, especially in patients with a history of liver disease.
  • Neutropenia: Obtain a complete blood count with white blood cell differential and direct platelet counts prior to and weekly during treatment.
  • Allergic reactions: Discontinue therapy if severe allergic reactions occur.
  • Storage: Store between 15°C and 25°C and avoid excessive heat.

Avoid Interactions

Chemet 100mg may interact with other medications, requiring careful monitoring.

Major Interactions (Avoid)

  • None identified.

Moderate Interactions (Monitor Closely)

  • Drugs that cause false positive results for ketones in urine using nitroprusside reagents.
  • Drugs that may interfere with serum uric acid and CPK measurements.
  • Drugs that may cause gastrointestinal symptoms or increases in serum transaminases.

Frequently Asked Questions

Chemet 100mg is used to treat lead poisoning in pediatric patients with blood lead levels above 45 µg/dL. It works by binding to lead and increasing its excretion in the urine, thereby reducing the risk of severe complications caused by lead poisoning.

Succimer, the active ingredient in Chemet 100mg, is a chelating agent that binds to heavy metals such as lead, mercury, and arsenic. It forms stable complexes with these metals, which are then excreted in the urine, helping to remove them from the body.

The dose of Chemet 100mg is determined by a healthcare professional based on the patient's weight and the severity of lead poisoning. Typically, it is administered every 8 hours for 5 days, followed by every 12 hours for an additional 14 days.

The safety of Chemet 100mg during pregnancy or breastfeeding has not been established. It should be used with caution and only if the potential benefits outweigh the risks. Consult a healthcare professional for personalized advice.

To order Chemet 100mg from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will then provide pricing, availability, shipping, and the necessary import paperwork.

Chemet 100mg is an orally active chelating agent specifically indicated for lead poisoning. It is often compared to intravenous CaNa2 EDTA, another chelating agent. Chemet 100mg is preferred for its oral administration and lower risk of adverse effects.

Chemet 100mg should be stored between 15°C and 25°C, avoiding excessive heat. It should be kept in the original packaging and protected from moisture. Ensure that the medication is stored out of reach of children and pets.

Chemet 100mg is administered orally. For young pediatric patients who cannot swallow capsules, the medicated beads can be sprinkled on a small amount of soft food or put in a spoon and followed with a fruit drink.

The most serious risks associated with Chemet 100mg include severe allergic reactions, significant elevations in serum transaminases indicating liver dysfunction, and severe neutropenia. Patients should be closely monitored for these adverse effects during therapy.

Chemet 100mg should not be used by patients with a history of allergy to the drug. It should be used with caution in patients with compromised renal or liver function. Always consult a healthcare professional before starting any new medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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