Product image of COPPER- cupric chloride injection (Cupric Chloride) 0.4mg/ml - 10ml Vials supplied by GNH India

COPPER- cupric chloride injection

Active Ingredient:
Cupric Chloride
Form:
Vials
Brand:
COPPER- cupric chloride injection
Origin:
USA

COPPER- cupric chloride injection (Cupric Chloride Vials) 0.4mg/ml - 10ml

Cupric chloride, the active ingredient in COPPER- cupric chloride injection, is a trace element presented as a 0.4 mg/mL solution in 10 mL vials for intravenous use. It is used as a supplement in total parenteral nutrition (TPN) to maintain copper levels and prevent deficiency symptoms in patients who cannot absorb nutrients orally.

GNH India supplies COPPER- cupric chloride injection as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

Strength

0.4mg/ml - 10ml

Pack Size

25s

Storage

Below 25°C

Manufacturer / TM Owner

Hospira Inc.

1
Pack/s
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Indications & Clinical Uses

COPPER- cupric chloride injection is indicated for use as a supplement to intravenous solutions given for total parenteral nutrition (TPN). It helps to maintain copper serum levels and prevent depletion of endogenous stores and subsequent deficiency symptoms.

  • Copper deficiency: Prevents and treats copper deficiency in patients receiving TPN.
  • Metabolic support: Supports essential metabolic functions in patients who cannot absorb nutrients orally.
  • Growth support: Helps meet increased copper requirements in infants and pediatric patients.

How It Works

  • Cupric chloride provides copper, an essential trace element that plays a crucial role in various enzymatic reactions and metabolic processes. Copper is necessary for the proper functioning of enzymes involved in energy production, iron metabolism, and the synthesis of neurotransmitters and connective tissue. It helps maintain the integrity of blood vessels, nerves, and bone.

Side Effects

COPPER- cupric chloride injection is generally well-tolerated, but like any medication, it may cause side effects.

Common Side Effects

  • Injection site reactions: Redness, swelling, or pain at the injection site.
  • Gastrointestinal disturbances: Nausea, vomiting, or diarrhea.
  • Allergic reactions: Rash, itching, or hives.

Serious or Rare Side Effects

  • Copper toxicity: Excessive copper can lead to toxicity, causing symptoms such as vomiting, diarrhea, and liver damage.
  • Aluminum toxicity: Prolonged use in patients with impaired kidney function may lead to aluminum accumulation, which can be toxic.
  • Tissue irritation: Direct intravenous injection may cause considerable tissue irritation due to the acidic pH of the solution.

Precautions & Warnings

COPPER- cupric chloride injection should be used with caution and under medical supervision.

  • Liver dysfunction: Liver and/or biliary tract dysfunction may require omission or reduction of copper doses.
  • Kidney impairment: Prolonged parenteral administration in patients with impaired kidney function may lead to aluminum toxicity.
  • Wilson's Disease: Not recommended for patients with Wilson's Disease due to abnormal copper metabolism.
  • Pregnancy and breastfeeding: Safety in pregnancy and breastfeeding has not been established; consult a healthcare provider.
  • Store at controlled room temperature (20-25°C): Keep in the original packaging, protect from light, and do not freeze.

Avoid Interactions

COPPER- cupric chloride injection may interact with other medications, necessitating careful monitoring.

Major Interactions (Avoid)

  • Antacids: May reduce the absorption of copper.
  • Zinc supplements: High doses of zinc can interfere with copper absorption.

Moderate Interactions (Monitor Closely)

  • Iron supplements: May affect copper metabolism and absorption.
  • Vitamin C: High doses of vitamin C may increase copper excretion.
  • Penicillamine: May increase copper excretion and lead to copper deficiency.

Frequently Asked Questions

COPPER- cupric chloride injection is used as a supplement in total parenteral nutrition (TPN) to maintain copper levels and prevent deficiency symptoms in patients who cannot absorb nutrients orally. It helps support essential metabolic functions and meets increased copper requirements in infants and pediatric patients.

Cupric chloride provides copper, an essential trace element that plays a crucial role in various enzymatic reactions and metabolic processes. Copper is necessary for the proper functioning of enzymes involved in energy production, iron metabolism, and the synthesis of neurotransmitters and connective tissue. It helps maintain the integrity of blood vessels, nerves, and bone.

The dosage of COPPER- cupric chloride injection is determined by a healthcare provider based on the patient's specific needs. For adults receiving TPN, the suggested additive dosage is 0.5 to 1.5 mg copper/day. For pediatric patients, the suggested additive dosage is 20 mcg copper/kg/day. Infants weighing less than 1500 grams may have increased requirements.

The safety of COPPER- cupric chloride injection during pregnancy and breastfeeding has not been established. It is important to consult a healthcare provider before using this medication if you are pregnant or breastfeeding.

To order COPPER- cupric chloride injection from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will reply with pricing, availability, shipping, and the import paperwork.

COPPER- cupric chloride injection is specifically formulated for intravenous use in patients receiving total parenteral nutrition (TPN). It provides a precise and controlled dose of copper to prevent deficiency symptoms. Other copper supplements may be available in oral forms, but they may not be suitable for patients who cannot absorb nutrients orally.

COPPER- cupric chloride injection should be stored at controlled room temperature (20-25°C). Keep the vials in the original packaging, protect from light, and do not freeze. Ensure that the solution is clear and free from particulate matter before administration.

COPPER- cupric chloride injection is administered intravenously only after dilution. The additive should be diluted in a volume of fluid not less than 100 mL. Direct intramuscular or intravenous injection is contraindicated due to the acidic pH of the solution, which may cause considerable tissue irritation.

The most serious risks associated with COPPER- cupric chloride injection include copper toxicity, aluminum toxicity, and tissue irritation. Copper toxicity can lead to symptoms such as vomiting, diarrhea, and liver damage. Aluminum toxicity may occur in patients with impaired kidney function. Tissue irritation can result from direct intravenous injection due to the acidic pH of the solution.

COPPER- cupric chloride injection should not be used by patients with Wilson's Disease due to abnormal copper metabolism. It should also be used with caution in patients with liver or biliary tract dysfunction, as well as those with impaired kidney function. Always consult a healthcare provider before using this medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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