Product image of Crusia (Enoxaparin Sodium) supplied by GNH India

Crusia

Active Ingredient:
Enoxaparin Sodium
Origin:
EU

Crusia (Enoxaparin Sodium)

Enoxaparin Sodium, the active ingredient in Crusia, is a low molecular weight heparin presented as a 120 mg/0.8 ml solution for subcutaneous or intravenous use. It is used for the prevention and treatment of blood clots in various clinical settings. GNH India supplies Crusia as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

Crusia is indicated for the prevention of deep vein thrombosis (DVT) in surgical patients, the treatment of acute DVT and pulmonary embolism, and anticoagulation during haemodialysis. It is a widely used anticoagulant that helps manage and prevent blood clots in high-risk patients.

Manufacturer / TM Owner

Laboratorios Farmacéuticos Rovi, S.A

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Crusia is an anticoagulant used to manage and prevent blood clots in various clinical settings. It is particularly effective in the following conditions:

  • Prevention of deep vein thrombosis (DVT) in surgical patients: Reduces the risk of blood clots forming in the legs during and after surgery.
  • Treatment of acute deep vein thrombosis and pulmonary embolism: Helps dissolve existing blood clots and prevents further clot formation.
  • Anticoagulation during haemodialysis: Ensures blood remains fluid during dialysis to prevent clotting in the extracorporeal circuit.

How It Works

  • Crusia works by binding to antithrombin III, a natural protein in the blood that inhibits blood clotting. This binding potentiates the inhibition of factor Xa and, to a lesser extent, factor IIa (thrombin), thereby reducing the blood's ability to form clots. This mechanism makes it effective in preventing and treating thromboembolic events.

Side Effects

Crusia, like other anticoagulants, can cause a range of side effects. Common side effects include:

Common Side Effects

  • Injection site reactions: Redness, swelling, or pain at the injection site.
  • Bleeding: Minor bleeding episodes such as nosebleeds or gum bleeding.
  • Bruising: Increased tendency to bruise easily.
  • Nausea: Mild stomach discomfort or nausea.

Serious or Rare Side Effects

  • Severe bleeding: Uncontrolled bleeding that can be life-threatening.
  • Allergic reactions: Severe allergic reactions, including anaphylaxis.
  • Thrombocytopenia: A decrease in platelet count, which can increase the risk of bleeding.
  • Osteoporosis: Long-term use may lead to bone thinning and increased fracture risk.

Precautions & Warnings

Crusia should be used with caution and under medical supervision. Important precautions include:

  • Monitoring: Regular blood tests to monitor clotting times and platelet counts.
  • Dosage adjustment: Adjusting the dose in patients with renal impairment or other risk factors for bleeding.
  • Surgery: Avoiding elective surgery while on Crusia to reduce the risk of bleeding.
  • Pregnancy: Consulting a healthcare provider before use during pregnancy or breastfeeding.
  • Store below 25°C: Keep in the original pack, protect from moisture and light, and do not freeze.

Avoid Interactions

Crusia can interact with other medications, potentially altering its effectiveness or increasing the risk of side effects. Major interactions include:

Major Interactions (Avoid)

  • Other anticoagulants: Concurrent use with warfarin or other anticoagulants can increase the risk of bleeding.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs): Increases the risk of gastrointestinal bleeding.
  • Antiplatelet drugs: Enhances the risk of bleeding when used together.

Moderate Interactions (Monitor Closely)

  • Thrombolytics: May increase the risk of bleeding when used with Crusia.
  • Certain antibiotics: Some antibiotics can alter the effectiveness of Crusia.
  • Herbal supplements: Some herbs, like ginkgo biloba, can increase the risk of bleeding.

Frequently Asked Questions

Crusia is used for the prevention and treatment of blood clots. It is particularly effective in preventing deep vein thrombosis (DVT) in surgical patients, treating acute DVT and pulmonary embolism, and ensuring anticoagulation during haemodialysis. Its active ingredient, Enoxaparin Sodium, helps manage and prevent thromboembolic events in high-risk patients.

Enoxaparin Sodium works by binding to antithrombin III, a natural protein in the blood that inhibits blood clotting. This binding potentiates the inhibition of factor Xa and, to a lesser extent, factor IIa (thrombin), thereby reducing the blood's ability to form clots. This mechanism makes it effective in preventing and treating thromboembolic events.

The dosage of Crusia is determined by a healthcare provider based on the patient's condition, weight, and other factors. It is crucial to follow the prescribed dosage and administration instructions provided by the healthcare professional to ensure safety and effectiveness.

The safety of Crusia during pregnancy or breastfeeding should be discussed with a healthcare provider. While it is often used in pregnant women at risk of blood clots, the decision to use it should be based on a thorough evaluation of the benefits and risks by a medical professional.

To order Crusia from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask the buyer to confirm trade or institutional credentials and will reply with pricing, availability, shipping, and the import paperwork.

Crusia is a low molecular weight heparin, which offers several advantages over traditional anticoagulants like warfarin. It has a more predictable anticoagulant effect, requires less frequent monitoring, and has a lower risk of certain side effects. However, the choice of anticoagulant depends on the specific needs and conditions of the patient.

Crusia should be stored below 25°C, kept in the original pack, and protected from moisture and light. It should not be frozen. Proper storage and handling are essential to maintain the effectiveness and safety of the medication. Always follow the storage instructions provided on the packaging.

Crusia is typically administered via subcutaneous injection or intravenous infusion, depending on the clinical setting and the patient's needs. The administration should be carried out by a healthcare professional to ensure proper dosage and technique. Always follow the administration instructions provided by the healthcare provider.

The most serious risks associated with Crusia include severe bleeding, allergic reactions, and thrombocytopenia. Patients should be monitored regularly for signs of bleeding, and any unusual symptoms should be reported to a healthcare provider immediately. Regular blood tests may be required to monitor clotting times and platelet counts.

Crusia should not be used by individuals with a known hypersensitivity to Enoxaparin Sodium or other low molecular weight heparins. It should also be used with caution in patients with a history of bleeding disorders, severe liver or kidney disease, or those undergoing major surgery. Always consult a healthcare provider before starting Crusia.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.