Product image of Dabigatran 110mg (Dabigatran Etexilate Mesilate ) 110mg Capsule supplied by GNH India

Dabigatran 110mg

Active Ingredient:
Dabigatran Etexilate Mesilate
Form:
Capsule
Brand:
Dabigatran 110mg
Origin:
India

Dabigatran 110mg (Dabigatran Etexilate Mesilate Capsule) 110mg

Dabigatran etexilate mesilate, the active ingredient in Dabigatran 110mg, is a direct thrombin inhibitor presented as a 110mg capsule for oral use. It is used to prevent stroke and systemic embolism in non-valvular atrial fibrillation and to treat and prevent deep vein thrombosis and pulmonary embolism.

GNH India supplies Dabigatran 110mg as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Strength

110mg

Pack Size

60s

Storage

Ambient

Manufacturer / TM Owner

Centurion Remedis Pvt Ltd

1
Pack/s
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Indications & Clinical Uses

Dabigatran 110mg is an anticoagulant used to manage and prevent blood clots. It is primarily indicated for the following conditions:

  • Non-valvular atrial fibrillation: Prevents stroke and systemic embolism in patients with one or more risk factors.
  • Deep vein thrombosis (DVT): Treats and prevents DVT and pulmonary embolism (PE) in adults.
  • Pulmonary embolism (PE): Prevents recurrent DVT and PE in adults.

How It Works

  • Dabigatran etexilate mesilate is a direct, reversible inhibitor of thrombin (factor IIa). It prevents the conversion of fibrinogen to fibrin, thereby inhibiting the formation of blood clots. This action helps to reduce the risk of stroke, systemic embolism, and other thromboembolic events.

Side Effects

Dabigatran 110mg may cause various side effects, ranging from common to serious or rare.

Common Side Effects

  • Nausea
  • Stomach pain
  • Indigestion
  • Bleeding (e.g., nosebleeds, bruising)
  • Anaemia

Serious or Rare Side Effects

  • Major gastrointestinal bleeding
  • Increased risk of bleeding in elderly patients (≥ 75 years)
  • Unexplained fall in haemoglobin or haematocrit
  • Unexplained low blood pressure
  • Severe allergic reactions

Precautions & Warnings

Dabigatran 110mg should be used with caution in certain conditions and populations. Precautions include:

  • Bleeding risk: Use with caution in patients with an increased risk of bleeding or with concomitant use of medicinal products affecting haemostasis.
  • Elderly patients: Dose reduction may be necessary for patients aged ≥80 years.
  • Renal impairment: Dose adjustment may be required for patients with moderate renal impairment.
  • Concomitant medications: Avoid or monitor closely when used with platelet aggregation inhibitors, NSAIDs, or other anticoagulants.
  • Storage: Store at room temperature between 59°F to 86°F (15°C to 30°C): Keep the medicine at a dry place, protect the capsules from moisture, and keep out of the reach of children. Once the bottle is opened, it should be used within 4 months.

Avoid Interactions

Dabigatran 110mg may interact with other medications, potentially affecting its efficacy or increasing the risk of side effects.

Major Interactions (Avoid)

  • Concomitant use with other anticoagulants (e.g., warfarin, heparin)
  • Use with strong P-glycoprotein inhibitors (e.g., ketoconazole, cyclosporine)

Moderate Interactions (Monitor Closely)

  • Use with platelet aggregation inhibitors (e.g., clopidogrel, aspirin)
  • Use with non-steroidal anti-inflammatory drugs (NSAIDs)
  • Use in patients with gastritis, esophagitis, or gastroesophageal reflux

Frequently Asked Questions

Dabigatran 110mg is used to prevent stroke and systemic embolism in patients with non-valvular atrial fibrillation and to treat and prevent deep vein thrombosis (DVT) and pulmonary embolism (PE). It is a direct thrombin inhibitor that helps to reduce the risk of blood clots.

Dabigatran etexilate mesilate works by directly inhibiting thrombin, a key enzyme in the blood clotting process. By inhibiting thrombin, it prevents the conversion of fibrinogen to fibrin, thereby reducing the formation of blood clots.

The usual dose of Dabigatran 110mg is determined by a healthcare professional based on the patient's condition, age, and other factors. It is typically taken as one 110mg capsule twice daily, but the prescriber sets the exact regimen.

The safety of Dabigatran 110mg during pregnancy or breastfeeding has not been established. It is generally recommended to avoid using this medication during pregnancy unless clearly necessary. Consult a healthcare professional for personalized advice.

To order Dabigatran 110mg from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will then provide pricing, availability, shipping, and the necessary import paperwork.

Dabigatran 110mg is a direct thrombin inhibitor, while warfarin is an anticoagulant that works by inhibiting vitamin K-dependent clotting factors. Dabigatran offers the advantage of fixed dosing without the need for regular monitoring of blood clotting levels, unlike warfarin, which requires frequent blood tests.

Dabigatran 110mg should be stored at room temperature between 59°F to 86°F (15°C to 30°C). Keep the medicine in a dry place, protect the capsules from moisture, and keep them out of the reach of children. Once the bottle is opened, it should be used within 4 months.

Dabigatran 110mg is administered orally in the form of capsules. The capsules should be swallowed whole with a glass of water, and they can be taken with or without food. The exact dosing regimen is determined by a healthcare professional.

The most serious risks associated with Dabigatran 110mg include major gastrointestinal bleeding, unexplained falls in haemoglobin or haematocrit, and severe allergic reactions. Patients should be monitored closely for signs of bleeding and other adverse effects.

Dabigatran 110mg should not be used by patients with prosthetic heart valves, those with active pathological bleeding, and those with a history of severe hypersensitivity to dabigatran. It should also be used with caution in patients with an increased risk of bleeding or with concomitant use of certain medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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