Definity (Perflutren) 6.52 mg

Definity (perflutren 6.52 mg) is an ultrasound contrast agent used to enhance echocardiogram images. It improves visualization of cardiac structures for diagnostic clarity. This sterile suspension is administered intravenously in clinical settings. Store at room temperature away from direct light.

Strength

6.52 mg

Pack Size

Storage

Ambient

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Pack/s

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Indications & Clinical Uses

Definity is used to improve the quality of ultrasound images of the heart, including left ventricular opacification and endocardial border delineation. It helps healthcare providers assess cardiac function and detect abnormalities. The contrast agent is particularly useful when standard imaging techniques yield suboptimal results. Definity is not intended for use in patients with known hypersensitivity to perflutren.

Side Effects

After administration, Definity produces microbubbles that reflect ultrasound waves, enhancing image contrast. Patients may experience a brief sensation of warmth or mild discomfort at the injection site. Some individuals report a metallic taste or mild headache following the procedure. These effects are generally transient and resolve quickly.

Precautions & Warnings

Definity should only be administered by trained healthcare professionals in a clinical setting equipped for emergency care. Patients with severe pulmonary hypertension or unstable cardiopulmonary conditions require careful monitoring. Avoid use in patients with right-to-left shunts or significant cardiac shunts. Inform your provider of any allergies or prior reactions to contrast agents.

Avoid Interactions

No specific drug interactions have been established with Definity. However, caution is advised when using other contrast agents or medications that may affect cardiac function. Alcohol and sedatives may potentiate drowsiness during the procedure. Always disclose all medications and supplements to your healthcare provider before receiving Definity.

Frequently Asked Questions

Definity is used to enhance ultrasound images of the heart, improving diagnostic accuracy for cardiac conditions.

Definity is given as an intravenous injection by a healthcare professional during an echocardiogram.

Mild side effects may include warmth, headache, or a metallic taste, which typically resolve quickly.

Inform your provider of any allergies, especially to perflutren or prior contrast agents, before receiving Definity.

Definity should be avoided in patients with certain cardiac conditions; a healthcare provider will assess suitability.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 29 Jul 2026

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