Product image of Olfen Hydrożel (Diclofenac Sodium) supplied by GNH India

Olfen Hydrożel

Active Ingredient:
Diclofenac Sodium
Origin:
EU

Olfen Hydrożel (Diclofenac Sodium)

Diclofenac sodium, the active ingredient in Olfen Hydrożel, is a non‑steroidal anti‑inflammatory drug presented as a topical hydrogel for dermal use. It is indicated for the relief of pain and inflammation associated with musculoskeletal conditions such as sprains, strains and osteoarthritis in adults.

GNH India supplies Olfen Hydrożel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Diclofenac sodium is a NSAID that reduces inflammation and pain in the musculoskeletal system.

  • Osteoarthritis: helps relieve joint pain and improve mobility.
  • Acute sprain or strain: reduces local inflammation and pain.
  • Post‑operative pain: provides topical analgesia after minor surgical procedures.

How It Works

  • Diclofenac sodium inhibits cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, decreasing the synthesis of prostaglandins that mediate inflammation, pain and fever. By limiting prostaglandin production at the site of application, the hydrogel delivers localized anti‑inflammatory activity with minimal systemic exposure.

Side Effects

Adverse reactions may occur with topical diclofenac use.

Common Side Effects

  • Skin irritation: redness, itching or burning at the application site.
  • Dryness: mild peeling or flaking of the skin.
  • Pruritus: localized itching.
  • Erythema: mild redness of the treated area.

Serious or Rare Side Effects

  • Contact dermatitis: severe allergic skin reaction.
  • Systemic NSAID effects: gastrointestinal discomfort, headache or dizziness.
  • Liver enzyme elevation: abnormal liver function tests.
  • Renal impairment: reduced kidney function in susceptible individuals.

Precautions & Warnings

When using Olfen Hydrożel, follow these safety guidelines:

  • Contraindications: avoid if known allergy to diclofenac or other NSAIDs.
  • Application area: limit to intact skin and avoid mucous membranes.
  • Duration of use: do not exceed the recommended treatment period without medical advice.
  • Concomitant NSAIDs: avoid using other topical or oral NSAIDs simultaneously.
  • Systemic conditions: use with caution in patients with cardiovascular, renal or hepatic disease.
  • Store at ambient temperature: keep below 25°C, in the original packaging, protected from moisture and direct sunlight.

Avoid Interactions

Diclofenac sodium may interact with several medicines; monitoring is advised.

Major Interactions (Avoid)

  • Anticoagulants: increased risk of bleeding.
  • Lithium: elevated lithium serum levels.
  • Methotrexate: enhanced methotrexate toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: possible reduction in renal function.
  • Diuretics: heightened risk of renal impairment.
  • Corticosteroids: additive gastrointestinal irritation.
  • Selective serotonin reuptake inhibitors (SSRIs): increased bleeding risk.

Frequently Asked Questions

Olfen Hydrożel is a topical gel that contains diclofenac sodium. It is used to relieve pain and reduce inflammation associated with musculoskeletal conditions such as osteoarthritis, sprains, strains and minor post‑surgical discomfort when applied to the affected skin area.

Diclofenac sodium blocks the cyclo‑oxygenase enzymes COX‑1 and COX‑2, which are needed to produce prostaglandins. By lowering prostaglandin levels at the site of application, the gel reduces inflammation, pain and swelling locally without significant systemic absorption.

The prescribed amount of Olfen Hydrożel is determined by a healthcare professional based on the patient’s condition, age and treatment area. The prescriber will advise how much gel to apply and how often, typically a thin layer to the affected skin several times daily.

Topical diclofenac should be used during pregnancy or breastfeeding only if clearly needed and after consulting a healthcare provider. Systemic absorption is low, but caution is advised, especially in the third trimester and while nursing, to avoid potential fetal or infant exposure.

To order Olfen Hydrożel, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Olfen Hydrożel delivers diclofenac sodium, a potent COX‑inhibitor, in a hydrogel base that provides rapid skin absorption. Compared with gels containing ibuprofen or ketoprofen, diclofenac often offers stronger anti‑inflammatory effects, though individual response varies and choice depends on clinician preference and patient tolerance.

Olfen Hydrożel should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight and extreme heat to maintain gel consistency and potency.

Apply a thin layer of the gel to clean, dry, intact skin over the painful area and gently rub it in. Follow the prescriber’s instructions regarding frequency, usually two to four times per day, and avoid covering the treated area with airtight dressings unless directed.

Serious risks include severe allergic skin reactions such as contact dermatitis, systemic NSAID effects like gastrointestinal bleeding, and potential kidney or liver function changes, especially in patients with pre‑existing organ disease or who use other NSAIDs concurrently.

Individuals with a known hypersensitivity to diclofenac, other NSAIDs, or any component of the gel should avoid its use. It is also contraindicated in patients with active gastrointestinal ulcers, severe heart failure, or uncontrolled renal or hepatic impairment unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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