Product image of Difen Ud (Diclofenac Sodium) supplied by GNH India

Difen Ud

Active Ingredient:
Diclofenac Sodium
Origin:
EU

Difen Ud (Diclofenac Sodium)

Diclofenac sodium, the active ingredient in Difen Ud, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a 1 mg/ml solution in single-dose containers for ocular use. It is used to treat postoperative ocular inflammation, pain, and other inflammatory conditions of the eye. GNH India supplies Difen Ud as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Difen Ud is formulated to provide targeted relief for various ocular conditions, leveraging the anti-inflammatory properties of diclofenac sodium. This medication is designed for easy application and is available in convenient single-dose containers to ensure sterility and ease of use.

Manufacturer / TM Owner

Pharma Stulln Gmbh

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Indications & Clinical Uses

Difen Ud is an NSAID used to manage inflammation and pain in the eye. It is particularly effective in treating conditions related to ocular inflammation and postoperative care.

  • Postoperative inflammation: Reduces inflammation following eye surgery, such as cataract operations or laser treatments.
  • Cystoid macular edema prevention: Helps prevent changes in the eye's macula after cataract surgery.
  • Non-infectious ocular inflammation: Treats inflammation in the eye that is not caused by infection.
  • Pain and photophobia: Alleviates pain and light sensitivity after refractive surgery.

How It Works

  • Diclofenac sodium works by inhibiting cyclooxygenase (COX) enzymes, which are involved in the production of prostaglandins. By reducing prostaglandin synthesis, diclofenac sodium decreases inflammation, pain, and other associated symptoms in the eye. This mechanism makes it effective for managing postoperative inflammation and other inflammatory conditions of the eye.

Side Effects

Difen Ud may cause several side effects, ranging from mild to severe.

Common Side Effects

  • Mild to moderate burning or stinging sensation in the eye immediately after application.
  • Temporary blurred vision.
  • Redness or itching of the eye.
  • Increased sensitivity to light.

Serious or Rare Side Effects

  • Severe allergic reactions, including swelling, rash, or difficulty breathing.
  • Corneal thinning or ulceration with prolonged use.
  • Increased risk of bleeding, especially in patients with a history of bleeding disorders.
  • Worsening of asthma or other respiratory conditions.

Precautions & Warnings

Difen Ud should be used with caution to ensure safety and effectiveness.

  • Allergies: Do not use if you are allergic to diclofenac sodium or any other components of the medication.
  • Pregnancy: Avoid use during the last trimester of pregnancy due to potential risks to the fetus.
  • Breastfeeding: Consult your healthcare provider before using while breastfeeding.
  • Infections: Use with caution in the presence of ocular infections, as it may mask symptoms.
  • Lenses: Remove contact lenses before application and wait at least 15 minutes before reinserting.
  • Storage: Store at room temperature (below 25°C): keep in the original pack, protect from moisture.

Avoid Interactions

Difen Ud may interact with other medications, potentially affecting its efficacy or increasing the risk of side effects.

Major Interactions (Avoid)

  • Other NSAIDs: Concurrent use with other NSAIDs can increase the risk of side effects.
  • Anticoagulants: May enhance the risk of bleeding when used together.
  • Corticosteroids: Prolonged use with corticosteroids can increase the risk of corneal thinning.

Moderate Interactions (Monitor Closely)

  • Diuretics: May reduce the effectiveness of diuretics.
  • ACE inhibitors: May increase the risk of kidney problems.
  • Lithium: May increase lithium levels in the blood, requiring close monitoring.

Frequently Asked Questions

Difen Ud is used to treat postoperative ocular inflammation, pain, and other inflammatory conditions of the eye. It is particularly effective in managing inflammation following eye surgeries such as cataract operations or laser treatments, and in preventing cystoid macular edema after cataract surgery.

Diclofenac sodium works by inhibiting cyclooxygenase (COX) enzymes, which are involved in the production of prostaglandins. By reducing prostaglandin synthesis, it decreases inflammation, pain, and other associated symptoms in the eye, making it effective for managing postoperative inflammation and other inflammatory conditions.

The dosage of Difen Ud is determined by a healthcare provider based on the specific condition being treated. Typically, it involves applying a certain number of drops at regular intervals before and after surgery, or as directed for other inflammatory conditions. Always follow the prescribed dosage and instructions provided by your healthcare professional.

Difen Ud should be avoided during the last trimester of pregnancy due to potential risks to the fetus. If you are breastfeeding, consult your healthcare provider before using this medication to ensure it is safe for both you and your baby.

To order Difen Ud from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask you to confirm your trade or institutional credentials. The team will then provide pricing, availability, shipping details, and the necessary import paperwork.

Difen Ud is specifically formulated with diclofenac sodium, which is known for its effective anti-inflammatory properties. Compared to other NSAID eye drops, it is designed for targeted relief of ocular inflammation and pain, particularly after surgery. The choice between different NSAID eye drops depends on the specific needs and conditions of the patient, as determined by a healthcare provider.

Difen Ud should be stored at room temperature (below 25°C) in the original pack, protecting it from moisture. Each single-dose container should be used immediately after opening and discarded after use to maintain sterility. Always follow the storage instructions provided with the medication to ensure its effectiveness and safety.

Difen Ud is administered as eye drops. The usual method involves tilting the head back, pulling down the lower eyelid to form a pocket, and applying the prescribed number of drops into the eye. After application, gently close the eye and press the inner corner of the eye for about a minute to prevent the medication from draining into the tear duct.

The most serious risks associated with Difen Ud include severe allergic reactions, such as swelling, rash, or difficulty breathing, as well as corneal thinning or ulceration with prolonged use. Patients with a history of bleeding disorders should use it with caution due to the increased risk of bleeding. Always consult a healthcare provider if you experience any severe or persistent side effects.

Difen Ud should not be used by individuals who are allergic to diclofenac sodium or any other components of the medication. It should also be avoided during the last trimester of pregnancy and used with caution in patients with a history of bleeding disorders or ocular infections. Always consult a healthcare provider to determine if Difen Ud is suitable for your specific condition.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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