Product image of Max Strength St. John’s Wort Holland & Barrett (Dry Extract From St. John's Wort Herb Equivalent To 711-995 Mg Of Herb, Extraction Solvent: Ethanol ) supplied by GNH India

Max Strength St. John’s Wort Holland & Barrett

Active Ingredient:
Dry Extract From St. John's Wort Herb Equivalent To 711-995 Mg Of Herb, Extraction Solvent: Ethanol
Origin:
EU

Max Strength St. John’s Wort Holland & Barrett (Dry Extract From St. John's Wort Herb Equivalent To 711-995 Mg Of Herb, Extraction Solvent: Ethanol)

St. John's wort, the active ingredient in Max Strength St. John's Wort Holland & Barrett, is a herbal supplement presented as a dry ethanol‑extracted herb extract for oral use. It is traditionally used to support mood and may be considered for mild to moderate depression in adults.

GNH India supplies Max Strength St. John's Wort Holland & Barrett as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide. The product complies with EU quality standards and is manufactured under GMP conditions, and is available for global distribution.

Manufacturer / TM Owner

Holland And Barrett International Limited

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Indications & Clinical Uses

Max Strength St. John's Wort Holland & Barrett, a herbal supplement, is used to support mood regulation and mild to moderate depressive symptoms.

  • Mild depression: may help improve mood and reduce depressive symptoms.
  • Moderate depression: used as adjunctive support for mood improvement.
  • Seasonal affective disorder: may alleviate seasonal mood changes.
  • Stress‑related mood disturbances: may aid coping with stress‑induced low mood.

How It Works

  • St. John's wort contains hypericin and hyperforin which modulate neurotransmitter activity. The extract inhibits serotonin reuptake and influences dopamine and norepinephrine pathways, increasing their synaptic concentrations. It also affects ion channels and inflammatory mediators, contributing to antidepressant‑like effects, and may modulate the hypothalamic‑pituitary‑adrenal axis to support stress response regulation.

Side Effects

Common Side Effects

  • Photosensitivity: increased sensitivity to sunlight.
  • Gastrointestinal upset: nausea, stomach discomfort.
  • Dry mouth: reduced salivation.
  • Dizziness: light‑headed sensation.
  • Headache: mild to moderate pain.
  • Fatigue: feeling of tiredness.

Serious or Rare Side Effects

  • Serotonin syndrome: potentially life‑threatening reaction when combined with serotonergic drugs.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • Liver toxicity: abnormal liver function tests.
  • Mania or hypomania induction: sudden elevation of mood in susceptible individuals.
  • Severe phototoxic skin reaction: blistering or burns with sun exposure.
  • Cardiac arrhythmia: irregular heart rhythm in rare cases.

Precautions & Warnings

Before using Max Strength St. John's Wort Holland & Barrett, consider the following precautions:

  • Pregnancy: safety not established; avoid use unless advised by a healthcare professional.
  • Breastfeeding: insufficient data; consider alternative therapies.
  • Drug interactions: review concomitant serotonergic or CYP‑inducing agents.
  • Photosensitivity: limit exposure to direct sunlight and use protective clothing.
  • Psychiatric conditions: monitor for emergence of mania or hypomania.
  • Store below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

St. John's wort may interact with several medicines; awareness of the interaction level is important.

Major Interactions (Avoid)

  • SSRIs: increased risk of serotonin syndrome.
  • MAO inhibitors: heightened serotonin syndrome risk.
  • Tricyclic antidepressants: elevated plasma concentrations.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible increase in anticoagulant effect.
  • Oral contraceptives: reduced hormonal efficacy.
  • Protease inhibitor antiretrovirals: altered drug metabolism leading to reduced effectiveness.

Frequently Asked Questions

Max Strength St. John's Wort Holland & Barrett is an oral herbal supplement that provides a dry ethanol‑extracted St. John's wort herb. It is commonly used to support mood and may be considered for mild to moderate depressive symptoms, including seasonal affective disorder and stress‑related low mood.

The active constituents of St. John's wort, such as hypericin and hyperforin, modulate neurotransmitter activity by inhibiting serotonin reuptake and influencing dopamine and norepinephrine pathways. This results in increased synaptic levels of these neurotransmitters, which can help improve mood and alleviate depressive symptoms.

The appropriate dose of Max Strength St. John's Wort Holland & Barrett is determined by a qualified prescriber based on the individual’s clinical condition, age, and other medications. Patients should follow the healthcare professional’s instructions and not self‑adjust the dosage.

Safety of St. John's wort in pregnancy and lactation has not been established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks with their healthcare provider before using this supplement.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Unlike synthetic antidepressants, Max Strength St. John's Wort is a plant‑derived extract that works primarily by modulating serotonin, dopamine, and norepinephrine reuptake. It may have a more favorable side‑effect profile for some users but carries a higher potential for drug‑drug interactions, especially with serotonergic medications.

Store the product below 25°C in a dry environment. Keep the original packaging closed, protect it from moisture and direct sunlight, and ensure the container is out of reach of children.

The supplement is taken orally, typically with water. The exact timing and frequency should follow the prescribing clinician’s guidance, which may recommend taking it with food to reduce gastrointestinal discomfort.

The most serious risks include the potential for serotonin syndrome when combined with other serotonergic agents, severe photosensitivity leading to sunburn‑like reactions, and rare cases of liver toxicity or manic episodes in susceptible individuals.

Individuals taking monoamine oxidase inhibitors, selective serotonin reuptake inhibitors, tricyclic antidepressants, or other serotonergic drugs should avoid this supplement unless directed by a healthcare professional. Those with a history of bipolar disorder, severe liver disease, or hypersensitivity to St. John's wort should also refrain from use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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