Humexphyto Sans Sucre Édulcorée Au Maltitol Liquide (Dry Extract Of Hederae Folium (Der 4-8:1), Extracting Agent: Ethanol 30 % (M/M))

Humexphyto Sans Sucre is indicated for temporary relief of cough and mucus accumulation associated with common respiratory conditions.

• Cough linked to acute upper respiratory infections such as the common cold.
• Productive (wet) cough due to bronchitis.
• Mild to moderate chest congestion with difficulty expectorating.
• Supportive care during the early phase of viral respiratory illness.
• Adjunctive use for individuals seeking a sugar‑free herbal expectorant.

• The dry extract of Hederae folium contains saponins and flavonoids that act on the respiratory epithelium. These constituents stimulate bronchial secretions and increase ciliary activity, promoting mucociliary clearance. By enhancing the volume and fluidity of airway mucus, the extract facilitates the mobilization and expectoration of sputum, helping to relieve productive coughs associated with acute respiratory infections and reduces irritation of the airway lining.

Adverse reactions to the ivy leaf liquid preparation are generally mild, but rare serious events have been reported.

Common

• Mild gastrointestinal discomfort such as nausea or abdominal cramps.
• Transient oral irritation or a bitter taste.
• Loose stools or mild diarrhea.
• Skin redness at the site of contact (if applied externally).
• Mild headache or dizziness.
• Transient increase in salivation.

Serious

• Allergic reactions including urticaria, angioedema, or anaphylaxis.
• Severe bronchospasm in individuals with known hypersensitivity to ivy.
• Hepatic enzyme elevation (rare).
• Persistent vomiting or severe abdominal pain.
• Liver function test abnormalities requiring medical evaluation.
• Swelling of the throat or tongue (angioedema).

When using Humexphyto Sans Sucre, certain precautions should be observed to minimize risk and ensure appropriate use.

• Do not use in children under 6 years of age without medical advice.
• Avoid use in individuals with known hypersensitivity to ivy or other Asteraceae plants.
• Pregnant or breastfeeding women should consult a healthcare professional before use.
• Patients with severe liver or kidney disease should seek medical guidance.
• Concomitant use with other expectorants or mucolytics should be discussed with a pharmacist.
• If symptoms persist longer than 7 days, discontinue and seek medical evaluation.

Potential interactions with other substances should be considered when taking this herbal expectorant.

Avoid

• Concurrent use with monoamine oxidase inhibitors (MAOIs) due to theoretical risk of bronchospasm.
• Combining with other strong expectorants or mucolytic agents without professional guidance.
• Use together with antihistamines that may mask cough improvement.
• Avoid simultaneous use with anticoagulant therapy as saponins may affect platelet function.

Use with caution

• Co‑administration with bronchodilators may enhance bronchodilatory effect; monitor for excessive airway relaxation.
• Herbal supplements containing similar saponin‑rich extracts (e.g., thyme, licorice) may increase cumulative expectorant activity.
• Alcohol consumption may increase ethanol exposure from the formulation; limit intake.
• When taken with CYP450‑metabolized drugs, monitor for possible alterations in drug levels, although evidence is limited.