Product image of Lamberts St John’s (Dry Extract Of St. John's Wort (5-7:1), Extraction Solvent: Ethanol 60% V/V) supplied by GNH India

Lamberts St John’s

Active Ingredient:
Dry Extract Of St. John's Wort (5-7:1), Extraction Solvent: Ethanol 60% V/V
Origin:
EU

Lamberts St John’s (Dry Extract Of St. John's Wort (5-7:1), Extraction Solvent: Ethanol 60% V/V)

Hypericum perforatum, the active ingredient in Lamberts St John’s, is a herbal supplement presented as a dry ethanol‑based extract for oral use. It is traditionally employed to support mood balance in adults experiencing mild to moderate depressive symptoms and seasonal affective changes.

GNH India supplies Lamberts St John’s as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution. Manufacturing follows EU Good Manufacturing Practice guidelines.

Manufacturer / TM Owner

Lamberts Healthcare Ltd.

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Indications & Clinical Uses

Lamberts St John’s, a herbal supplement, is used for mood‑related disorders that involve neurotransmitter imbalances.

  • Mild to moderate depression: helps improve mood and reduce depressive symptoms.
  • Seasonal affective disorder: alleviates seasonal mood changes and low energy.
  • Stress‑related mood disturbances: supports emotional resilience during periods of heightened stress.

How It Works

  • Hypericum perforatum contains hypericin and hyperforin, which inhibit the reuptake of serotonin and modulate dopamine and norepinephrine pathways. The extract also influences GABAergic activity and may affect ion channel function, resulting in a net increase of synaptic neurotransmitter availability that contributes to mood stabilization.

Side Effects

Lamberts St John’s may cause a range of adverse reactions.

Common Side Effects

  • Gastrointestinal upset: nausea, abdominal discomfort, or loose stools.
  • Headache: mild to moderate intensity.
  • Dizziness: transient light‑headedness.
  • Skin photosensitivity: increased sensitivity to sunlight.

Serious or Rare Side Effects

  • Serotonin syndrome: risk when combined with serotonergic drugs, presenting with agitation, hyperthermia, and neuromuscular abnormalities.
  • Severe allergic reactions: rash, swelling, or anaphylaxis.
  • Liver enzyme elevation: abnormal hepatic function tests.

Precautions & Warnings

Before using Lamberts St John’s, consider the following precautions.

  • Avoid use with serotonergic antidepressants: risk of serotonin syndrome.
  • Do not operate heavy machinery if dizziness occurs.
  • Monitor for photosensitivity: limit exposure to direct sunlight.
  • Pregnancy and breastfeeding: use only if benefits outweigh potential risks.
  • Discontinue if severe skin reactions develop.
  • Store at ambient temperature: keep in the original pack, protect from moisture and light.

Avoid Interactions

Lamberts St John’s can interact with several medicines.

Major Interactions (Avoid)

  • SSRIs and SNRIs: increased risk of serotonin syndrome.
  • MAO inhibitors: potential hypertensive crisis and serotonin syndrome.
  • Anticoagulants (e.g., warfarin): enhanced bleeding tendency.
  • Oral contraceptives: reduced hormonal efficacy.

Moderate Interactions (Monitor Closely)

  • Tricyclic antidepressants: altered plasma concentrations.
  • Antiepileptics (e.g., phenytoin): decreased effectiveness.
  • Immunosuppressants (e.g., cyclosporine): reduced drug levels.

Frequently Asked Questions

Lamberts St John’s is an herbal supplement containing a dry extract of Hypericum perforatum. It is traditionally used to support mood balance in adults experiencing mild to moderate depressive symptoms and seasonal affective disorder.

The extract modulates neurotransmitter activity by inhibiting serotonin reuptake and influencing dopamine and norepinephrine pathways. It also affects GABAergic signaling, which together may improve mood and emotional stability.

The appropriate dosage is determined by the prescribing healthcare professional based on individual needs and product labeling. Patients should follow the prescriber’s instructions and not self‑adjust the dose.

Safety data are limited. It is generally advised to avoid use during pregnancy and lactation unless the prescriber determines that potential benefits outweigh potential risks.

Submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Unlike synthetic antidepressants, Lamberts St John’s is a herbal extract with a milder pharmacological profile. It may have fewer drug‑interaction risks but generally offers less potency, making it more suitable for mild to moderate mood disturbances rather than severe depression.

Store the product at ambient temperature, below 25 °C, in the original packaging, protected from moisture, heat and direct sunlight to maintain stability.

The supplement is taken orally, usually with water, and can be taken with or without food as directed by the prescriber.

The most serious risks include serotonin syndrome when combined with serotonergic drugs, severe allergic reactions, and potential liver enzyme elevation. Immediate medical attention is required if any of these events occur.

Individuals currently taking SSRIs, SNRIs, MAO inhibitors, anticoagulants, oral contraceptives, or those with known hypersensitivity to Hypericum species should avoid this supplement unless advised otherwise by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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