Product image of Egaten 250mg (Triclabendazole) 250mg Tablet supplied by GNH India

Egaten 250mg

Active Ingredient:
Triclabendazole
Form:
Tablet
Brand:
Egaten
Origin:
France

Egaten 250mg (Triclabendazole Tablet) 250mg

Triclabendazole, the active ingredient in Egaten 250mg, is an anthelmintic presented as a 250mg tablet for oral use. It is used to treat fascioliasis, a parasitic infection caused by the liver fluke Fasciola hepatica or Fasciola gigantica.

GNH India supplies Egaten 250mg as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Strength

250mg

Pack Size

4s

Storage

Ambient

Manufacturer / TM Owner

Novartis Pharma S.A.S.

1
Pack/s
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Indications & Clinical Uses

Egaten 250mg is an antiparasitic medication used to treat infections caused by liver flukes.

  • Fascioliasis: Treats infections caused by Fasciola hepatica or Fasciola gigantica, which can lead to liver damage and other complications.
  • Distomatose hépatique: Addresses liver fluke infections that cause liver disease and related symptoms.
  • Parasitic infections: Effective against certain types of parasitic worms that affect the liver and bile ducts.

How It Works

  • Triclabendazole works by binding to the parasite's β-tubulin, disrupting microtubule formation and inhibiting glucose uptake. This leads to energy depletion and ultimately the death of the parasite, effectively treating the infection.

Side Effects

Egaten 250mg may cause several side effects, ranging from common to serious.

Common Side Effects

  • Abdominal pain, including upper abdominal pain.
  • Nausea.
  • Vomiting.
  • Diarrhea.
  • Constipation.
  • Malaise.

Serious or Rare Side Effects

  • Hepatic effects, including jaundice and liver enzyme abnormalities.
  • Back pain.
  • Chest pain or discomfort.
  • Difficulty breathing.
  • Fever.
  • Yellow skin or eyes.

Precautions & Warnings

Before taking Egaten 250mg, certain precautions should be considered.

  • Allergies: Do not take if allergic to triclabendazole or any other benzimidazole derivatives.
  • Liver disease: Use with caution if you have liver or biliary issues.
  • Glucose-6-Phosphate Dehydrogenase deficiency: May cause hemolysis in individuals with this condition.
  • Heart conditions: Caution is advised for those with heart rhythm disorders or electrolyte imbalances.
  • Kidney disease: Use with caution if you have kidney problems.
  • Pregnancy and breastfeeding: Avoid unless necessary, and discontinue breastfeeding for 72 hours after the last dose.
  • Store below 30°C: Keep in the original packaging, protect from moisture and light.

Avoid Interactions

Egaten 250mg may interact with other medications, potentially affecting its efficacy or increasing the risk of side effects.

Major Interactions (Avoid)

  • Other medications that prolong the QT interval.
  • Medications that cause electrolyte imbalances, particularly low potassium or magnesium levels.

Moderate Interactions (Monitor Closely)

  • Medications metabolized by the liver, as triclabendazole may affect liver enzymes.
  • Antispasmodics or other medications used to manage symptoms of parasitic infections.
  • Medications that may cause hemolysis in individuals with glucose-6-phosphate dehydrogenase deficiency.

Frequently Asked Questions

Egaten 250mg is used to treat fascioliasis, a parasitic infection caused by the liver flukes Fasciola hepatica or Fasciola gigantica. It is effective in addressing liver fluke infections that can lead to liver damage and other complications.

Triclabendazole works by binding to the parasite's β-tubulin, disrupting microtubule formation and inhibiting glucose uptake. This leads to energy depletion and ultimately the death of the parasite, effectively treating the infection.

The dose of Egaten 250mg is determined by a healthcare professional based on the patient's weight and the severity of the infection. Typically, the recommended dose is 10 milligrams per kilogram of body weight, and in severe cases, additional doses may be administered.

Egaten 250mg should be avoided during pregnancy unless necessary, as its safety has not been established. If you are breastfeeding, you should discontinue breastfeeding for 72 hours after the last dose of Egaten 250mg.

To order Egaten 250mg from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will then provide pricing, availability, shipping, and the necessary import paperwork.

Egaten 250mg is specifically effective against liver flukes and is considered one of the primary treatments for fascioliasis. Compared to other antiparasitic medications, it is unique in its ability to target and eliminate liver flukes, making it a crucial option for this specific type of parasitic infection.

Egaten 250mg should be stored at a temperature not exceeding 30°C, in its original packaging, and protected from moisture and light. It is important to keep the medication out of the reach of children and to follow the storage instructions provided on the packaging.

Egaten 250mg is taken orally, preferably after a meal. The tablets can be taken whole or divided into two parts and swallowed with a little water. In some cases, the tablet may be crushed and mixed with semi-solid food like apple compote for easier administration.

The most serious risks associated with Egaten 250mg include hepatic effects such as jaundice and liver enzyme abnormalities, as well as potential heart rhythm disorders. Patients should monitor for symptoms like abdominal pain, yellowing of the skin or eyes, and difficulty breathing, and seek medical attention if these occur.

Egaten 250mg should not be taken by individuals who are allergic to triclabendazole or any other benzimidazole derivatives. It should also be avoided by those with severe liver or kidney disease, glucose-6-phosphate dehydrogenase deficiency, or certain heart conditions, unless specifically advised by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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