Lidocaína / Epinefrina Dermogen (Epinephrine Bitartrate, Lidocaine Hydrochloride)

Lidocaine blocks voltage‑gated sodium channels on peripheral nerves, preventing the initiation and propagation of action potentials. This interruption of nerve signaling results in loss of sensation in the injected area, delivering rapid and reversible anesthesia.

The dose is determined by the prescribing clinician based on the procedure, patient weight, and maximum allowable lidocaine limits. Healthcare professionals calculate the appropriate volume to achieve effective anesthesia while staying within safety guidelines.

Safety data are limited, and the product should only be used during pregnancy or lactation if the potential benefit justifies any potential risk. The prescriber must evaluate the clinical situation and discuss possible effects with the patient.

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The addition of epinephrine causes local vasoconstriction, which prolongs the anesthetic effect of lidocaine, reduces systemic absorption, and minimizes intra‑operative bleeding. Plain lidocaine lacks these vasoconstrictive benefits and may require higher or repeated dosing for comparable duration.

Store the sterile injectable solution at room temperature, below 25 °C. Keep it in the original container, protect from moisture and direct sunlight, and discard any product that appears cloudy or contains particles.

The product is administered by infiltration injection directly into the target tissue using aseptic technique. The prescriber selects the appropriate needle gauge and injection volume to achieve adequate anesthesia of the intended area.

Serious risks include severe allergic reactions (anaphylaxis), cardiac arrhythmias or hypertension from epinephrine, central nervous system toxicity such as seizures from lidocaine excess, and rare cases of methemoglobinemia. Immediate medical attention is required if these occur.

Patients with known hypersensitivity to lidocaine, other amide‑type local anesthetics, or epinephrine should avoid this product. It is also contraindicated in individuals with uncontrolled hypertension, certain cardiac conduction disorders, or those taking monoamine oxidase inhibitors without careful supervision.