Lidocaína/Adrenalina Normogen (Epinephrine, Lidocaine Hydrochloride)

Lidocaine blocks voltage‑gated sodium channels on nerve fibers, stopping the transmission of pain signals. Epinephrine activates alpha‑adrenergic receptors, causing local vasoconstriction. This vasoconstriction limits systemic absorption of lidocaine, prolonging its anesthetic effect and decreasing intra‑operative bleeding.

The specific dose and volume are determined by the prescribing clinician based on the type of procedure, patient size, and clinical judgment. Healthcare professionals calculate the appropriate amount to achieve effective anesthesia while staying within safe limits for both lidocaine and epinephrine.

Safety data for use in pregnancy and lactation are limited. The product should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and it should be prescribed by a qualified healthcare provider after careful assessment.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and required import documentation.

Compared with lidocaine alone, the addition of epinephrine in Normogen prolongs the duration of anesthesia, reduces the required total dose of lidocaine, and minimizes bleeding at the injection site. However, the epinephrine component introduces additional cardiovascular considerations, such as potential hypertension or tachycardia, which are not present with plain lidocaine.

Lidocaína/Adrenalina Normogen should be stored at ambient temperature, below 25 °C, in its original sealed container. Protect the product from direct sunlight, moisture and extreme temperature fluctuations. Do not freeze the solution, and inspect the vial for particulate matter before use.

The product is administered by a qualified healthcare professional via injection. It can be injected directly into the tissue for local infiltration or placed adjacent to a peripheral nerve for a regional block. Proper aseptic technique and dosage calculation are essential for safe and effective use.

Serious risks include severe allergic reactions such as anaphylaxis, cardiac arrhythmias, and marked hypertension due to the epinephrine component. Immediate medical attention is required if signs of these reactions appear, such as chest pain, rapid heartbeat, difficulty breathing, or a sudden rise in blood pressure.

The product should be avoided in individuals with known hypersensitivity to lidocaine, epinephrine, or any excipients, as well as patients with uncontrolled hypertension, significant cardiac disease, or those taking non‑selective MAO inhibitors. Contraindications also include patients with severe hyperthyroidism or pheochromocytoma.