Lidocaïne / Adrenaline Aguettant (Epinephrine, Lidocaine Hydrochloride)

Lidocaine blocks voltage‑gated sodium channels on nerve membranes, preventing the initiation and propagation of action potentials. This interruption stops pain signals from reaching the brain. Epinephrine added to the formulation constricts local blood vessels, limiting lidocaine’s systemic absorption and thereby prolonging its numbing effect.

The specific dose and volume are determined by the prescribing clinician based on the type of procedure, patient weight, and anatomical site. Healthcare professionals calculate the amount needed to stay within safe maximum limits for lidocaine and epinephrine, and the product is administered only under medical supervision.

Safety data for this combination in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any possible risk to the fetus or infant. Clinicians should assess each case individually and discuss potential concerns with the patient before administration.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Plain lidocaine provides rapid local anesthesia but is absorbed more quickly, leading to a shorter duration of action and increased bleeding at the site. The addition of epinephrine in Lidocaïne / Adrenaline Aguettant constricts blood vessels, prolongs the anesthetic effect, reduces intra‑operative bleeding, and lowers the total amount of lidocaine needed for effective analgesia.

Lidocaïne / Adrenaline Aguettant should be stored at room temperature, below 25 °C, in its original sealed container. Protect the solution from direct sunlight, moisture, and extreme temperature fluctuations. Do not freeze the product; inspect for particulate matter before use and discard if the solution appears discoloured or cloudy.

The product is administered by a qualified healthcare professional via injection. Common routes include epidural, infiltration, or perineural injection, depending on the clinical indication. The clinician selects the appropriate needle size, injection technique, and volume to achieve effective anesthesia while adhering to safety guidelines.

Serious risks include severe allergic reactions (anaphylaxis), cardiovascular events such as arrhythmias, myocardial ischemia, or hypertensive crisis due to systemic epinephrine, and central nervous system toxicity like seizures from excessive lidocaine absorption. Immediate medical attention is required if any of these symptoms occur.

Patients with known hypersensitivity to lidocaine, epinephrine, or any component of the formulation should avoid this product. It is also contraindicated in individuals with uncontrolled hypertension, severe cardiac disease, certain arrhythmias, or those taking non‑selective MAO inhibitors. Clinicians must evaluate each patient’s medical history before prescribing.