Product image of Lignospan Special utilycaine – Lignokent – Eurocaine - Rexocaine (Epinephrine, Lidocaine Hydrochloride) supplied by GNH India

Lignospan Special utilycaine – Lignokent – Eurocaine - Rexocaine

Active Ingredient:
Epinephrine, Lidocaine Hydrochloride
Origin:
EU

Lignospan Special utilycaine – Lignokent – Eurocaine - Rexocaine (Epinephrine, Lidocaine Hydrochloride)

Lidocaine Hydrochloride, the active ingredient in Lignospan Special, is a local anesthetic presented as a sterile solution for infiltration use. It provides rapid onset numbness for minor surgical, dental and dermatologic procedures in adult patients.
GNH India supplies Lignospan Special as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Septodont Ltd.

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Indications & Clinical Uses

Lignospan Special is a local anesthetic used in procedures that require temporary loss of sensation.

  • Minor surgical procedures: provides rapid and reliable surface anesthesia.
  • Dental extractions and restorations: enables painless treatment of teeth and gums.
  • Dermatologic interventions: numbs skin for biopsies, excisions or laser therapy.
  • Endoscopic examinations: reduces discomfort during short‑duration mucosal inspections.

How It Works

  • Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, preventing the initiation and propagation of action potentials. Epinephrine activates alpha‑adrenergic receptors on local blood vessels, causing vasoconstriction that limits systemic absorption of lidocaine, prolongs its anesthetic effect, and reduces bleeding at the injection site.

Side Effects

Adverse reactions may occur with any local anesthetic containing epinephrine.

Common Side Effects

  • Transient pain or burning at the injection site
  • Mild tachycardia or palpitations
  • Temporary increase in blood pressure
  • Nausea or light‑headedness
  • Dizziness or feeling of warmth
  • Metallic taste in the mouth

Serious or Rare Side Effects

  • Allergic reaction or anaphylaxis
  • Severe arrhythmia or cardiac ischemia
  • Seizures due to high plasma lidocaine levels
  • Prolonged numbness or paresthesia
  • Tissue necrosis from excessive vasoconstriction
  • Cardiovascular collapse in susceptible patients

Precautions & Warnings

Use of Lignospan Special requires careful assessment of patient risk factors.

  • Cardiac history: patients with hypertension, arrhythmias or coronary disease may be sensitive to epinephrine effects.
  • Lidocaine allergy: avoid in individuals with known hypersensitivity to amide‑type local anesthetics.
  • Pregnancy and lactation: limited safety data; use only if benefit outweighs potential risk.
  • Monitor vital signs: observe blood pressure and heart rate during and after injection.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Lignospan Special can interact with drugs that affect cardiovascular function or sodium channel activity.

Major Interactions (Avoid)

  • Beta‑blockers: may exacerbate hypertension and tachycardia caused by epinephrine.
  • Monoamine oxidase inhibitors (MAOIs): increased risk of hypertensive crisis.
  • Tricyclic antidepressants: may enhance lidocaine‑related cardiotoxicity.

Moderate Interactions (Monitor Closely)

  • Other vasoconstrictors: additive increase in blood pressure.
  • Class I antiarrhythmic agents: potential for synergistic arrhythmias.
  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): may mask pain, leading to over‑use of anesthetic.

Frequently Asked Questions

Lignospan Special is a combination of lidocaine and epinephrine used to provide local anesthesia for minor surgical, dental and dermatologic procedures. The epinephrine component prolongs the anesthetic effect and reduces bleeding at the injection site.

Lidocaine blocks voltage‑gated sodium channels on nerve membranes, preventing the generation and conduction of nerve impulses. This results in a reversible loss of sensation in the area where the drug is infiltrated.

The exact dose of Lignospan Special is determined by the prescribing clinician based on the procedure, patient size, and anatomical site. Healthcare professionals calculate the appropriate volume to achieve effective anesthesia while staying within safe limits.

Safety data for Lignospan Special in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and the decision should be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with lidocaine alone, Lignospan Special contains epinephrine, which causes local vasoconstriction. This prolongs the anesthetic duration, reduces systemic absorption, and minimizes intra‑procedural bleeding, making it preferable for procedures where a longer effect and a clearer surgical field are desired.

Store Lignospan Special at room temperature, preferably below 25 °C. Keep the vial in its original packaging, protect it from direct light and moisture, and ensure the container is tightly sealed to maintain sterility.

Lignospan Special is administered by infiltration injection directly into the tissue surrounding the target area. The clinician injects the solution using a sterile needle, allowing the anesthetic to take effect within minutes.

Serious risks include allergic reactions such as anaphylaxis, severe cardiovascular events like arrhythmias or myocardial ischemia, and central nervous system toxicity leading to seizures. Immediate medical attention is required if any of these symptoms occur.

Patients with a known hypersensitivity to lidocaine, other amide‑type local anesthetics, or epinephrine should avoid Lignospan Special. It is also contraindicated in individuals with certain severe cardiac conditions where epinephrine‑induced vasoconstriction could be harmful.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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