Product image of Lidocaína + Adrenalina Normon (Epinephrine, Lidocaine Hydrochloride) supplied by GNH India

Lidocaína + Adrenalina Normon

Active Ingredient:
Epinephrine, Lidocaine Hydrochloride
Origin:
EU

Lidocaína + Adrenalina Normon (Epinephrine, Lidocaine Hydrochloride)

Lidocaine hydrochloride, the active ingredient in Lidocaína + Adrenalina Normon, is a local anesthetic presented as an injection solution for intra‑arterial and intravenous use. It provides local anesthesia for minor surgical or diagnostic procedures and helps control bleeding during such interventions.

GNH India supplies Lidocaína + Adrenalina Normon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratórios Normon, S.A.

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Indications & Clinical Uses

Lidocaína + Adrenalina Normon is a local anesthetic with vasoconstrictor properties used in procedures that require temporary loss of sensation and reduced bleeding.

  • Minor surgical procedures: provides reliable local anesthesia to facilitate the operation.
  • Diagnostic procedures: enables painless tissue sampling or endoscopic examination.
  • Bleeding control during procedures: vasoconstriction reduces blood loss and improves visual field.

How It Works

  • Lidocaine blocks voltage‑gated sodium channels on neuronal membranes, preventing depolarisation and impulse transmission. Epinephrine stimulates alpha‑adrenergic receptors on vascular smooth muscle, causing vasoconstriction that prolongs lidocaine’s effect, limits systemic absorption, and reduces intra‑procedural bleeding.

Side Effects

Adverse reactions may occur following administration of the lidocaine‑epinephrine combination.

Common Side Effects

  • Tachycardia: rapid heart rate after injection.
  • Hypertension: transient increase in blood pressure.
  • Nausea: mild gastrointestinal upset.
  • Local irritation: redness or discomfort at the injection site.
  • Dizziness: brief sense of light‑headedness.
  • Headache: mild to moderate pain.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Seizures: central nervous system excitation, especially with high plasma lidocaine levels.
  • Cardiac arrhythmia: irregular heart rhythm that may be life‑threatening.
  • Myocardial ischemia: reduced blood flow to heart muscle.
  • Methemoglobinemia: abnormal hemoglobin causing reduced oxygen delivery.

Precautions & Warnings

When using Lidocaína + Adrenalina Normon, clinicians should observe specific safety measures.

  • Cardiovascular assessment: monitor heart rate and blood pressure before and after administration.
  • Allergy screening: verify no known hypersensitivity to lidocaine or epinephrine.
  • Dosage calculation: adjust dose based on patient weight, age, and comorbidities.
  • Concomitant drugs: review other vasoconstrictors or anti‑arrhythmic agents.
  • Patient monitoring: observe for signs of systemic toxicity during and after the procedure.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Lidocaína + Adrenalina Normon may interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Beta‑blockers: can exacerbate hypertension and reduce epinephrine effectiveness.
  • Monoamine oxidase inhibitors (MAOIs): increase risk of hypertensive crisis.
  • Tricyclic antidepressants: may potentiate lidocaine cardiotoxicity.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): may increase bleeding tendency.
  • Calcium channel blockers: can augment cardiovascular effects of epinephrine.
  • Diuretics: may alter plasma concentrations of lidocaine.

Frequently Asked Questions

Lidocaína + Adrenalina Normon is an injectable combination of lidocaine and epinephrine used to provide local anesthesia for minor surgical or diagnostic procedures and to reduce bleeding by causing vasoconstriction at the treatment site.

Lidocaine blocks voltage‑gated sodium channels on nerve fibers, preventing the initiation and propagation of action potentials, which results in loss of sensation in the targeted area.

The appropriate dose is determined by the prescribing clinician based on the specific procedure, patient weight, age, and overall health status. No fixed regimen is provided here.

Safety data are limited; the product should only be used during pregnancy or lactation if the potential benefit justifies the potential risk, and this decision must be made by the treating physician.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Adding epinephrine to lidocaine prolongs the anesthetic effect, reduces systemic absorption, and provides vasoconstriction that helps control bleeding, whereas plain lidocaine lacks these vasoconstrictive benefits.

Store at ambient temperature, ideally below 25 °C, in the original sealed container. Protect from direct light and moisture, and discard any solution that appears discoloured or contains particles.

The solution is administered by a qualified healthcare professional via intra‑arterial or intravenous injection, directly into the tissue or vessel that requires anesthesia and vasoconstriction.

Serious risks include anaphylaxis, seizures, cardiac arrhythmias, myocardial ischemia, and severe hypertension. Immediate medical intervention is required if any of these events occur.

Patients with known hypersensitivity to lidocaine, epinephrine, or any component of the formulation, as well as those with uncontrolled severe hypertension, certain cardiac conduction disorders, or recent use of MAO inhibitors, should avoid this product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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