Ergocalciferol (Ergocalciferol)

Trade Name : Ergocalciferol

Bryant Ranch Prepack

CAPSULE, LIQUID FILLED

Strength 1.25 mg/1

ERGOCALCIFEROL Ergocalciferols [CS],Provitamin D2 Compound [EPC]

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Ergocalciferol (Ergocalciferol) which is also known as Ergocalciferol and Manufactured by Bryant Ranch Prepack. It is available in strength of 1.25 mg/1 per ml. Read more

Ergocalciferol (Ergocalciferol) is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

Packaging and Delivery

Validated Cold Chain Shipment

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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About GNH

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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  • No data
  • Rx only
  • ERGOCALCIFEROL CAPSULES, USP, is a synthetic calcium regulator for oral administration.
  • Ergocalciferol is a white, colorless crystal, insoluble in water, soluble in organic solvents, and slightly soluble in vegetable oils. It is affected by air and by light. Ergosterol or provitamin D is found in plants and yeast and has no antirachitic activity.
  • There are more than 10 substances belonging to a group of steroid compounds, classified as having vitamin D or antirachitic activity.
  • One USP Unit of vitamin D is equivalent to one International Unit (IU), and 1 mcg of vitamin D is equal to 40 IU.
  • Each softgel, for oral administration, contains Ergocalciferol, USP 1.25 mg (equivalent to 50,000 USP units of Vitamin D), in an edible vegetable oil.
  • Ergocalciferol, also called vitamin D, is 9,10-secoergosta-5,7,10(19),22-tetraen-3-ol,(3,5,7,22)-; (CHO) with a molecular weight of 396.65, and has the following structural formula:
  • Inactive Ingredientsn- :
  • Theu00a0u00a0synthesis of the major biologically active metabolites of vitamin D occurs in two steps. The first hydroxylation of ergocalciferol takes place in the liver (to 25-hydroxyvitamin D) and the second in the kidneys (to 1,25-dihydroxyvitamin D). Vitamin D metabolites promote the active absorption of calcium and phosphorous by the small intestine, thus elevating serum calcium and phosphate levels sufficiently to permit bone mineralization. Vitamin D metabolites also mobilize calcium and phosphate from bone and probably increase the reabsorption of calcium and perhaps also of phosphate by the renal tubules.
  • There is a time lag of 10 to 24 hours between the administration of vitamin D and the initiation of its action in the body due to the necessity of synthesis of the active metabolites in the liver and kidneys.u00a0Parathyroid hormone is responsible for the regulation of this metabolism in the kidneys.
  • Ergocalciferol is indicated for use in the treatment of hypoparathyroidism, refractory rickets, also known as vitamin D resistant rickets, and familial hypophosphatemia.
  • Ergocalciferol is contraindicated in patients with hypercalcemia, malabsorption syndrome, abnormal sensitivity to the toxic effects of vitamin D, and hypervitaminosis D.
  • Hypersensitivity to vitamin D may be one etiologic factor in infants with idiopathic hypercalcemia. In these cases vitamin D must be strictly restricted.
  • Keep out of the reach of children.
  • No data
  • Hypervitaminosis D is characterized by effects on the following organ system:
  • Renal:
  • CNS:
  • Soft Tissues:
  • Skeletal:
  • Decline in the average rate of linear growth and increased mineralization of bones in infants and children (dwarfism), vague aches, stiffness, and weakness.
  • Gastrointestinal:
  • Metabolic:
  • To report SUSPECTED ADVERSE REACTIONS, contact Bionpharma at 1-888-235-2466 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch
  • The effects of administered vitamin D can persist for two or more months after cessation of treatment.
  • Hypervitaminosis D is characterized by:
  • The treatment of hypervitaminosis D with hypercalcemia consists in immediate withdrawal of the vitamin, a low calcium diet, generous intake of fluids, along with symptomatic and supportive treatment. Hypercalcemic crisis with dehydration, stupor, coma, and azotemia requires more vigorous treatment. The first step should be hydration of the patient. Intravenous saline may quickly and significantly increase urinary calcium excretion. A loop diuretic (furosemide or ethacrynic acid) may be given with the saline infusion to further increase renal calcium excretion. Other reported therapeutic measures include dialysis or the administration of citrates, sulfates, phosphates, corticosteroids, EDTA (ethylenediaminetetraacetic acid), and mithramycin via appropriate regimens. With appropriate therapy, recovery is the usual outcome when no permanent damage has occurred. Deaths via renal or cardiovascular failure have been reported.
  • The LD in animals is unknown. The toxic oral dose of ergocalciferol in the dog is 4 mg/kg.
  • THE RANGE BETWEEN THERAPEUTIC AND TOXIC DOSES IS NARROW.
  • Vitamin D Resistant Rickets:
  • Hypoparathyroidism:
  • DOSAGE MUST BE INDIVIDUALIZED UNDER CLOSE MEDICAL SUPERVISION.
  • Calcium intake should be adequate. Blood calcium and phosphorous determinations must be made every 2 weeks or more frequently if necessary. X-rays of the bones should be taken every month until condition is corrected and stabilized.
  • Product: 71335-1275
  • NDC: 71335-1275-1 4 CAPSULE, LIQUID FILLED in a BOTTLE
  • NDC: 71335-1275-2 12 CAPSULE, LIQUID FILLED in a BOTTLE
  • No data

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