Erwinase - UK (Crisantaspase Vials) 10,000 IU

Erwinase (Crisantaspase) is an enzyme-based medication supplied as 10,000 IU vials for injection. Used in the UK to support certain chemotherapy regimens. Store between 2–8°C to maintain potency. Always follow healthcare provider guidance when using.

Strength

10,000 IU

Pack Size

Storage

2-8°

Manufacturer / TM Owner

Porton Biopharma Limited, UK

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Pack/s

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Indications & Clinical Uses

Erwinase (Crisantaspase) is primarily used as part of combination chemotherapy for acute lymphoblastic leukemia (ALL). It works by breaking down asparagine, a nutrient some cancer cells need to grow. This medication is often prescribed when other asparaginase formulations are not suitable. Always consult your oncologist to determine if Erwinase is appropriate for your treatment plan.

Side Effects

Erwinase helps reduce abnormal cell growth by depleting asparagine levels in the bloodstream. Patients may experience temporary changes in appetite or mild digestive discomfort during treatment. Some individuals report feeling fatigued or noticing minor skin sensitivity. These effects vary and should be monitored by a healthcare professional.

Precautions & Warnings

Keep Erwinase refrigerated between 2–8°C to preserve its effectiveness. Protect vials from light and avoid freezing. Always handle with sterile technique when preparing doses. Inform your healthcare provider about any allergies or previous reactions to asparaginase before starting treatment.

Avoid Interactions

Erwinase may interact with medications that affect the immune system, such as immunosuppressants or corticosteroids. Combining it with certain vaccines (especially live vaccines) could reduce vaccine effectiveness. Alcohol and herbal supplements may also influence how your body responds to treatment. Discuss all current medications with your doctor.

References

Frequently Asked Questions

Erwinase is used in chemotherapy regimens, particularly for acute lymphoblastic leukemia (ALL). It helps reduce cancer cell growth by depleting asparagine.

Store Erwinase vials at 2–8°C and protect them from light. Avoid freezing to maintain potency.

Erwinase requires a prescription and should only be obtained through licensed pharmacies or healthcare providers.

Common effects may include fatigue, digestive discomfort, or skin sensitivity. Always report persistent symptoms to your doctor.

Erwinase contains the active ingredient crisantaspase, which is a type of asparaginase but may differ in formulation and origin.

Published by GNH India Pharmaceuticals Limited

Last updated: 17 Jun 2026

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