Product image of Estradot 50 (Estradiol) 50mcg/24hrs PATCH supplied by GNH India

Estradot 50

Active Ingredient:
Estradiol
Form:
PATCH
Brand:
Estradot
Origin:
Switzerland

Estradot 50 (Estradiol PATCH) 50mcg/24hrs

Estradiol, the active ingredient in Estradot 50, is an estrogen presented as a 50mcg/24hrs transdermal patch for transdermal use. It is used to relieve menopausal symptoms and treat estrogen deficiency in postmenopausal women. GNH India supplies Estradot 50 as a licensed, GDP-compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Estradot 50 is a hormone replacement therapy (HRT) designed to deliver estradiol through the skin, providing a steady release of the hormone to alleviate symptoms associated with menopause.

Strength

50mcg/24hrs

Pack Size

8s

Storage

Ambient

Manufacturer / TM Owner

NOVARTIS PHARMA SCHWEIZ

1
Pack/s
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Indications & Clinical Uses

Estradot 50 is used in hormone replacement therapy (HRT) to address conditions related to estrogen deficiency.

  • Menopausal symptoms: Relieves symptoms such as hot flashes, night sweats, and vaginal dryness.
  • Estrogen deficiency: Treats conditions arising from low estrogen levels in postmenopausal women.
  • Osteoporosis prevention: Helps prevent bone loss and reduces the risk of fractures in postmenopausal women with a high risk of osteoporosis.

How It Works

  • Estradot 50 works by delivering estradiol, a form of estrogen, through the skin into the bloodstream. Estradiol binds to estrogen receptors in the body, modulating gene transcription and restoring estrogen activity in target tissues. This helps alleviate menopausal symptoms and treat estrogen deficiency by mimicking the effects of natural estrogen.

Side Effects

Estradot 50 may cause various side effects, ranging from common to serious.

Common Side Effects

  • Skin irritation at the application site.
  • Breast tenderness or swelling.
  • Headache.
  • Nausea.
  • Abdominal bloating.
  • Vaginal bleeding or spotting.

Serious or Rare Side Effects

  • Increased risk of blood clots.
  • Stroke or heart attack.
  • Breast cancer.
  • Endometrial cancer (in women with a uterus).
  • Gallbladder disease.
  • Liver problems.

Precautions & Warnings

Estradot 50 should be used with caution and under medical supervision.

  • Consult a healthcare provider: Before starting Estradot 50, discuss your medical history and any existing conditions.
  • Regular monitoring: Regular check-ups are recommended to monitor for side effects and efficacy.
  • Avoid smoking: Smoking increases the risk of serious side effects.
  • Inform healthcare provider: Inform your healthcare provider about all medications you are taking.
  • Pregnancy and breastfeeding: Estradot 50 is not recommended during pregnancy or breastfeeding.
  • Storage: Store below 25°C: Keep in the original pack, protect from moisture.

Avoid Interactions

Estradot 50 may interact with other medications, potentially affecting its efficacy or increasing the risk of side effects.

Major Interactions (Avoid)

  • Anticoagulants: May increase the risk of bleeding.
  • Tamoxifen: May reduce the effectiveness of tamoxifen.

Moderate Interactions (Monitor Closely)

  • Anticonvulsants: May reduce the effectiveness of Estradot 50.
  • Antidepressants: May increase the risk of side effects.
  • Thyroid hormones: May affect thyroid hormone levels.

Frequently Asked Questions

Estradot 50 is used to relieve menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. It is also used to treat estrogen deficiency in postmenopausal women and to prevent osteoporosis.

Estradot 50 delivers estradiol through the skin into the bloodstream. Estradiol binds to estrogen receptors in the body, modulating gene transcription and restoring estrogen activity in target tissues, which helps alleviate menopausal symptoms and treat estrogen deficiency.

The usual dose of Estradot 50 is determined by a healthcare provider based on individual needs. The patch is typically changed twice a week, and the dosage may be adjusted to achieve the desired therapeutic effect.

Estradot 50 is not recommended during pregnancy or breastfeeding. Women should consult their healthcare provider before using Estradot 50 if they are pregnant, planning to become pregnant, or breastfeeding.

To order Estradot 50 from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will reply with pricing, availability, shipping, and the import paperwork.

Estradot 50 is a transdermal patch that delivers estradiol, a form of estrogen, through the skin. It is designed to provide a steady release of the hormone, which can help alleviate menopausal symptoms and treat estrogen deficiency. Compared to oral HRT, transdermal patches may have a lower risk of certain side effects, such as blood clots.

Estradot 50 should be stored below 25°C, kept in the original pack, and protected from moisture. The patch should be applied to clean, dry skin and changed twice a week. Avoid exposing the patch to direct sunlight or heat.

Estradot 50 is administered as a transdermal patch. The patch is applied to clean, dry skin on the lower abdomen, buttocks, or outer arm. It should be changed twice a week, and the application site should be rotated to prevent skin irritation.

The most serious risks associated with Estradot 50 include an increased risk of blood clots, stroke, heart attack, breast cancer, and endometrial cancer (in women with a uterus). Regular monitoring by a healthcare provider is recommended to manage these risks.

Estradot 50 should not be used by women who have a history of breast cancer, endometrial cancer, blood clots, liver disease, or unexplained vaginal bleeding. Women who are pregnant, planning to become pregnant, or breastfeeding should also avoid using Estradot 50.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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