Product image of Mostrelαn (Famotidine) supplied by GNH India

Mostrelαn

Active Ingredient:
Famotidine
Origin:
EU

Mostrelαn (Famotidine)

Famotidine, the active ingredient in Mostrelαn, is a H2 receptor antagonist presented as an oral dosage form for oral use. It reduces gastric acid secretion and is employed in the management of ulcer disease and gastro‑oesophageal reflux in adult patients and related acid‑related conditions. The drug is commonly prescribed worldwide and has a well‑established safety profile.

GNH India supplies Mostrelαn as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide with reliable logistics and regulatory support.

Manufacturer / TM Owner

Bennett Pharmaceuticals Sa

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Indications & Clinical Uses

Famotidine acts on acid‑related gastrointestinal conditions by inhibiting gastric acid secretion.

  • Peptic ulcer disease: promotes ulcer healing by lowering stomach acidity.
  • Gastro‑oesophageal reflux disease (GERD): relieves heartburn and esophageal irritation through acid reduction.
  • Erosive oesophagitis: facilitates mucosal recovery by decreasing acid exposure.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid production associated with gastrin‑secreting tumors.

How It Works

  • Famotidine competitively and reversibly binds to histamine H2 receptors located on the parietal cells of the gastric mucosa. By blocking histamine‑induced stimulation, it prevents the activation of the adenylate cyclase pathway, thereby reducing cyclic AMP formation and subsequent proton pump activity. This inhibition leads to a sustained reduction in gastric acidity, aiding in the treatment of acid‑related disorders.

Side Effects

Famotidine may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Headache: mild headache reported in some patients.
  • Dizziness: transient light‑headedness.
  • Constipation: reduced bowel movements.
  • Nausea: occasional feeling of queasiness.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Hepatic dysfunction: signs of liver injury such as jaundice.
  • Neutropenia: marked decrease in neutrophil count increasing infection risk.

Precautions & Warnings

When prescribing Famotidine, clinicians should consider several precautionary measures to ensure safe use.

  • Renal function assessment: adjust dose in patients with impaired renal clearance.
  • Elderly monitoring: observe for increased sensitivity to side effects.
  • Drug interaction review: evaluate concomitant medications that may affect acid suppression.
  • Discontinuation guidance: avoid abrupt cessation in patients with severe ulcer disease.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Famotidine can interact with other medicines, influencing its efficacy or safety.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: reduce famotidine absorption.
  • Ketoconazole: decreased antifungal effectiveness due to reduced gastric acidity.
  • Atazanavir: impaired antiviral absorption leading to subtherapeutic levels.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential increase in INR, requiring closer coagulation monitoring.
  • Theophylline: possible elevation of plasma theophylline concentrations.

Frequently Asked Questions

Mostrelαn contains famotidine, which is used to treat acid‑related gastrointestinal conditions such as peptic ulcer disease, gastro‑oesophageal reflux disease (GERD), erosive oesophagitis, and Zollinger‑Ellison syndrome. By lowering stomach acidity, it helps heal ulcers and relieve heartburn symptoms.

Famotidine works by competitively and reversibly blocking histamine H2 receptors on gastric parietal cells. This inhibition prevents histamine‑stimulated activation of the adenylate cyclase pathway, reducing cyclic AMP and ultimately decreasing gastric acid secretion.

The appropriate dose of famotidine is determined by the prescribing clinician based on the specific indication, patient age, renal function, and severity of disease. Typical adult regimens range from 20 mg to 40 mg once or twice daily, but exact dosing should follow the prescriber’s order.

Safety data for famotidine in pregnancy and lactation are limited. The medication should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a qualified health professional.

To request Mostrelαn, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Famotidine belongs to the H2 receptor antagonist class, offering rapid onset and a favorable safety profile compared with proton‑pump inhibitors (PPIs). While PPIs provide longer‑lasting acid suppression, H2 antagonists like famotidine are useful for on‑demand relief and have fewer drug‑interaction concerns with certain antivirals and antifungals.

Store Mostrelαn at ambient temperature, preferably below 25 °C. Keep the tablets in their original packaging, protect them from moisture, excessive heat and direct sunlight to maintain potency throughout the shelf life.

Mostrelαn is taken orally, with or without food, as directed by the prescriber. The tablets should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed.

Serious adverse reactions, although rare, include anaphylaxis, severe hepatic dysfunction, and neutropenia. Patients should seek immediate medical attention if they experience signs of allergic reaction, jaundice, or unexplained infections.

Famotidine is contraindicated in individuals with known hypersensitivity to the drug or any other H2‑receptor antagonist. Caution is also advised for patients with severe renal impairment, as dose adjustment may be required.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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