Fibrogen - I (Human Fibrinogen Vials) 1g

Human Fibrogen I is a sterile, lyophilized powder for intravenous use containing human fibrinogen 1g per vial. It is indicated for the treatment of acute bleeding episodes in patients with congenital fibrinogen deficiency. Store between 2-8°C to maintain potency.

Strength

Pack Size

Storage

2-8°

Manufacturer / TM Owner

Intas Pharmaceuticals Ltd

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Indications & Clinical Uses

Human Fibrogen I is used to manage acute bleeding in patients with congenital fibrinogen deficiency, a rare blood clotting disorder. It may also be used perioperatively to prevent excessive bleeding during surgical procedures in such patients. This treatment helps restore normal fibrinogen levels to support blood clot formation.

Side Effects

Human Fibrogen I works by replenishing fibrinogen, a protein essential for blood clotting. After administration, it integrates into the clotting cascade to help form stable clots and reduce bleeding. Patients may notice improved clotting ability and reduced bleeding symptoms following treatment.

Precautions & Warnings

Human Fibrogen I should be handled with care to avoid contamination. It must be reconstituted with sterile water before intravenous administration by a healthcare professional. Patients should be monitored for signs of allergic reactions or thrombosis during and after administration.

Avoid Interactions

Human Fibrogen I may interact with medications that affect blood clotting, such as anticoagulants or antiplatelet drugs. Concurrent use with these agents could alter clotting efficacy. Patients should inform their healthcare provider about all medications they are taking before receiving this treatment.

References

Frequently Asked Questions

Human Fibrogen I is used to treat acute bleeding in patients with congenital fibrinogen deficiency.

It is administered intravenously after reconstitution with sterile water by a healthcare professional.

Allergic reactions are possible; patients should be monitored during administration.

Safety during pregnancy has not been established; consult a healthcare provider.

Store between 2-8°C and protect from light until ready for use.

Published by GNH India Pharmaceuticals Limited

Last updated: 17 Jun 2026

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