Product image of Firmagon 120mg (Degarelix ) 120 mg Vials supplied by GNH India

Firmagon 120mg

Active Ingredient:
Degarelix
Form:
Vials
Brand:
Firmagon
Origin:
Germany

Firmagon 120mg (Degarelix Vials) 120 mg

Degarelix, the active ingredient in Firmagon 120mg, is a gonadotropin-releasing hormone (GnRH) antagonist presented as a 120 mg vial for subcutaneous use. It is used in the treatment of advanced hormone-sensitive prostate cancer and metastatic prostate cancer in adult men.

GNH India supplies Firmagon 120mg as a licensed, GDP-compliant international pharmaceutical supplier serving oncology centres worldwide.

Strength

120 mg

Pack Size

2s

Storage

Ambient

Manufacturer / TM Owner

Ferring GMBH Germany

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Firmagon 120mg is a gonadotropin-releasing hormone (GnRH) antagonist used in the treatment of prostate cancer. It is indicated for the following conditions:

  • Advanced hormone-sensitive prostate cancer: Reduces testosterone levels to slow the progression of the disease.
  • Metastatic prostate cancer: Helps manage the spread of cancer by suppressing testosterone production.
  • High-risk prostate cancer before radiotherapy: Prepares patients for subsequent treatment by reducing tumor growth.

How It Works

  • Degarelix works by competitively antagonizing GnRH receptors, which suppresses the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This reduction in LH and FSH leads to a decrease in testosterone production, thereby inhibiting the growth of prostate cancer cells.

Side Effects

Firmagon 120mg may cause various side effects, which can be categorized as follows:

Common Side Effects

  • Injection site reactions such as pain, swelling, and redness.
  • Hot flashes and sweating.
  • Fatigue and weakness.
  • Nausea and diarrhea.
  • Increased liver enzymes.
  • Muscle and joint pain.
  • Weight gain.
  • Headache and dizziness.

Serious or Rare Side Effects

  • Severe allergic reactions.
  • Heart problems, including heart failure and arrhythmias.
  • Increased risk of infections due to suppressed immune function.
  • Bone fractures and osteoporosis.
  • Depression and mood changes.
  • High blood sugar levels.

Precautions & Warnings

Firmagon 120mg should be used with caution and under medical supervision. Important precautions include:

  • Allergies: Do not use if allergic to degarelix or any of the other ingredients.
  • Heart conditions: Use with caution in patients with heart disease or a history of heart failure.
  • Bone health: Monitor for bone fractures and osteoporosis, especially with long-term use.
  • Diabetes: Regularly monitor blood sugar levels as degarelix may affect glucose metabolism.
  • Infections: Be aware of an increased risk of infections due to suppressed immune function.
  • Injection site: Avoid injecting in areas exposed to pressure or near ribs.
  • Store at 2-8°C: Keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Firmagon 120mg may interact with other medications, which can be categorized as follows:

Major Interactions (Avoid)

  • Other GnRH agonists or antagonists: Concurrent use may lead to additive effects and increased side effects.
  • Drugs metabolized by CYP3A4: Degarelix may inhibit CYP3A4, leading to increased levels of these drugs.
  • Anticoagulants: Increased risk of bleeding due to potential interactions.

Moderate Interactions (Monitor Closely)

  • Corticosteroids: May increase the risk of infections and bone fractures.
  • Diuretics: May affect electrolyte balance and increase the risk of dehydration.
  • Antidiabetic drugs: May require dose adjustments due to changes in blood sugar levels.

Frequently Asked Questions

Firmagon 120mg is used to treat advanced hormone-sensitive prostate cancer and metastatic prostate cancer in adult men. It works by reducing testosterone levels, which helps slow the progression of the disease.

Degarelix is a gonadotropin-releasing hormone (GnRH) antagonist. It works by blocking GnRH receptors, which suppresses the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This leads to a decrease in testosterone production, thereby inhibiting the growth of prostate cancer cells.

The usual starting dose of Firmagon 120mg is two initial injections of 120 mg, followed by monthly injections of 80 mg. The exact dosage and schedule should be determined by a healthcare professional based on the patient's condition.

Firmagon 120mg is not indicated for use in women, and its safety during pregnancy or breastfeeding has not been established. It should be used with caution in women of childbearing potential, and effective contraception should be used during treatment.

To order Firmagon 120mg from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will reply with pricing, availability, shipping, and the necessary import paperwork.

Firmagon 120mg is a GnRH antagonist, which differs from GnRH agonists like leuprolide and goserelin. Unlike agonists, antagonists like degarelix do not cause an initial surge in testosterone levels, which can help avoid potential tumor flare-ups. The choice between these treatments depends on individual patient factors and should be discussed with a healthcare professional.

Firmagon 120mg should be stored at 2-8°C, protected from light, and not frozen or shaken. The reconstituted solution should be used immediately to avoid microbial contamination. Always follow the storage instructions provided with the product.

Firmagon 120mg is administered as a subcutaneous injection. The injection should be given by a healthcare professional, and the injection site should be varied within the abdominal region to avoid areas exposed to pressure or near ribs.

The most serious risks associated with Firmagon 120mg include severe allergic reactions, heart problems, increased risk of infections, bone fractures, and depression. Patients should be monitored closely for these potential side effects, and any concerning symptoms should be reported to a healthcare professional immediately.

Firmagon 120mg should not be used by individuals who are allergic to degarelix or any of the other ingredients in the product. It should also be used with caution in patients with heart disease, bone health issues, diabetes, or a history of severe allergic reactions. Always consult a healthcare professional before starting treatment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Degarelix

Firmagon 80mg

Firmagon 80mg

80mg Vials
Degarelix Accord

Degarelix Accord
Degarelix Accord

Degarelix Accord
Degarelix Accord

Degarelix Accord

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT