Product image of Floxedol (Ofloxacin) supplied by GNH India

Floxedol

Active Ingredient:
Ofloxacin
Origin:
EU

Floxedol (Ofloxacin)

Ofloxacin, the active ingredient in Floxedol, is a fluoroquinolone antibiotic presented as a gel for ocular use. It is indicated for the treatment of various bacterial eye infections in adults and children over one year of age. GNH India supplies Floxedol as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Floxedol is designed to target and treat a range of bacterial eye infections, ensuring effective management of conditions such as conjunctivitis, blepharitis, and keratitis.

Manufacturer / TM Owner

Laboratório Edol - Produtos Farmacêuticos, S.A.

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Indications & Clinical Uses

Floxedol is indicated for the treatment of various bacterial eye infections. It is effective against a range of microorganisms sensitive to ofloxacin, including:

  • Bacterial conjunctivitis: Reduces inflammation and infection in the conjunctiva.
  • Blepharitis: Treats inflammation of the eyelids caused by bacterial infection.
  • Blepharoconjunctivitis: Addresses simultaneous inflammation of the eyelids and conjunctiva.
  • Dacryocystitis: Manages infections of the lacrimal sac.
  • Keratitis: Treats bacterial ulcers in the cornea.

How It Works

  • Ofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and transcription. By blocking these enzymes, ofloxacin prevents bacterial cells from replicating and transcribing genetic material, leading to the death of the bacteria.

Side Effects

Floxedol may cause several side effects, ranging from common to serious or rare. Common Side Effects:

  • Eye irritation
  • Burning or stinging sensation
  • Temporary blurred vision
  • Itching
  • Redness of the eye

Serious or Rare Side Effects

  • Allergic reactions, such as rash, itching, or swelling
  • Severe eye pain
  • Vision changes
  • Signs of a new infection, such as increased redness, swelling, or discharge.

Precautions & Warnings

Floxedol should be used with caution and under medical supervision. Important precautions include:

  • Avoid contact with soft contact lenses: Remove lenses before use and wait 15 minutes before reinserting.
  • Inform your doctor if you have a history of eye diseases or allergies: This includes conditions like corneal damage or dry eyes.
  • Use as directed: Do not exceed the prescribed dosage or duration of treatment.
  • Monitor for signs of allergic reactions: Discontinue use and seek medical attention if symptoms occur.
  • Store below 25°C: Keep in the original pack, protect from moisture.

Avoid Interactions

Floxedol may interact with other medications, potentially affecting its efficacy or increasing the risk of side effects. Major Interactions (Avoid):

  • Other ocular antibiotics: Concurrent use may increase the risk of side effects.
  • Corticosteroids: May reduce the effectiveness of Floxedol.

Moderate Interactions (Monitor Closely)

  • Anticoagulants: May increase the risk of bleeding.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs): May increase the risk of gastrointestinal side effects.
  • Other eye medications: May cause interactions or increased side effects.

Frequently Asked Questions

Floxedol is used to treat various bacterial eye infections, including conjunctivitis, blepharitis, blepharoconjunctivitis, dacryocystitis, and keratitis. It is effective against microorganisms sensitive to ofloxacin, the active ingredient.

Ofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes crucial for DNA replication and transcription. By blocking these enzymes, it prevents bacterial cells from replicating and transcribing genetic material, leading to their death.

The usual dose of Floxedol is determined by a healthcare professional based on the specific condition and severity of the infection. It is typically applied as directed by the prescribing doctor.

The safety of Floxedol during pregnancy or breastfeeding has not been established. It is important to consult a healthcare professional before using Floxedol if you are pregnant, planning to become pregnant, or breastfeeding.

To order Floxedol from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will then provide pricing, availability, shipping, and import paperwork.

Floxedol is a fluoroquinolone antibiotic, which is effective against a broad range of bacterial eye infections. Compared to other classes of antibiotics, fluoroquinolones are known for their potent antibacterial activity and are often used for more severe or resistant infections.

Floxedol should be stored below 25°C, kept in the original pack, and protected from moisture. It is important to follow the storage instructions provided to maintain the efficacy and safety of the medication.

Floxedol is administered as an ocular gel. It is applied directly to the affected eye(s) as directed by a healthcare professional. It is important to follow the prescribed dosage and administration instructions.

The most serious risks to watch for with Floxedol include allergic reactions, severe eye pain, vision changes, and signs of a new infection. If any of these symptoms occur, discontinue use and seek medical attention immediately.

Floxedol should not be used by individuals who are allergic to ofloxacin or any of the other ingredients in the medication. It is also not recommended for children under one year of age unless specifically directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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