Product image of Fluanxol Depot (Flupentixol ) 20mg/ml x 1ml Ampoules supplied by GNH India

Fluanxol Depot

Active Ingredient:
Flupentixol
Form:
Ampoules
Brand:
Fluanxol Depot
Origin:
India

Fluanxol Depot (Flupentixol Ampoules) 20mg/ml x 1ml

Flupentixol, the active ingredient in Fluanxol Depot, is a typical antipsychotic (thioxanthene derivative) presented as a 20mg/ml ampoule for intramuscular use. It is used in the management of schizophrenia and depressive disorders. GNH India supplies Fluanxol Depot as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Fluanxol Depot is manufactured by H. Lundbeck A/S and is available in India. It is indicated for the maintenance therapy of chronic schizophrenic patients and for the treatment of depressive disorders. The medication works by affecting the balance of certain natural substances in the brain, specifically by blocking dopamine receptors.

Strength

20mg/ml x 1ml

Pack Size

1s

Storage

Ambient

Manufacturer / TM Owner

H. Lundbeck A/S

1
Pack/s
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Indications & Clinical Uses

Fluanxol Depot is primarily used for the management of schizophrenia and depressive disorders. It works by affecting the balance of certain natural substances in the brain.

  • Schizophrenia: Used for the maintenance therapy of chronic schizophrenic patients whose main manifestations do not include excitement, agitation, or hyperactivity.
  • Depressive disorders: Used to treat depression, including depression with or without anxiety.
  • Psychotic disorders: May be used to treat other psychotic disorders as determined by a healthcare professional.

How It Works

  • Flupentixol, the active ingredient in Fluanxol Depot, acts as a dopamine D2 receptor antagonist with some serotonin receptor activity. It inhibits dopamine-mediated effects by blocking postsynaptic dopamine receptors in the central nervous system, which helps to alter thoughts and elevate mood, improving the person’s ability to think, feel, and behave.

Side Effects

Fluanxol Depot may cause several side effects, ranging from common to serious or rare.

Common Side Effects

  • Dry mouth
  • Abnormality of voluntary movements
  • Urinary retention
  • Constipation
  • Muscle rigidity
  • Dizziness and sleepiness
  • Weight gain
  • Injection site reactions such as pain, redness, or swelling

Serious or Rare Side Effects

  • Rigidity, tremors, restlessness, and tardive dyskinesia
  • Insomnia
  • Sexual dysfunction
  • Galactorrhoea and menstrual disturbances
  • Neuroleptic malignant syndrome (hyperthermia, hypertonicity of skeletal muscles, unconsciousness, and autonomic nervous system instability)

Precautions & Warnings

Fluanxol Depot should be used with caution and under the supervision of a healthcare professional. It is important to inform your doctor about any other medications you are taking to avoid potential interactions.

  • Administration: Should be administered by a healthcare professional and should not be self-administered.
  • Dosing: Take it at the same time each day as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better.
  • Sudden discontinuation: This medication must not be stopped suddenly without talking to your doctor as it may worsen your symptoms.
  • Driving and operating machinery: May cause dizziness and sleepiness; do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Weight gain: This medicine can lead to weight gain; have a healthy balanced diet and exercise regularly.
  • Storage: Store in a cool and dry place, and keep the temperature below 30°C.

Avoid Interactions

Fluanxol Depot may interact with other medications, which can affect its efficacy or increase the risk of side effects.

Major Interactions (Avoid)

  • Alcohol: Potentiates CNS effects, leading to increased drowsiness.
  • General anaesthetics, hypnotics, anxiolytics, and opioids: Potentiates CNS effects.
  • Guanethidine: Blocks antihypertensive effect.

Moderate Interactions (Monitor Closely)

  • Antimuscarinic effects (e.g., TCAs): May potentiate the adverse effects.
  • Levodopa: Reduced efficacy of levodopa.
  • Dopamine antagonists (e.g., metoclopramide and prochlorperazine): Increases adverse extrapyramidal symptoms.

Frequently Asked Questions

Fluanxol Depot is primarily used for the management of schizophrenia and depressive disorders. It works by affecting the balance of certain natural substances in the brain, specifically by blocking dopamine receptors. This helps to alter thoughts and elevate mood, improving the person’s ability to think, feel, and behave.

Flupentixol, the active ingredient in Fluanxol Depot, acts as a dopamine D2 receptor antagonist with some serotonin receptor activity. It inhibits dopamine-mediated effects by blocking postsynaptic dopamine receptors in the central nervous system. This action helps to alter thoughts and elevate mood, improving the person’s ability to think, feel, and behave.

The dose of Fluanxol Depot is determined by a healthcare professional based on the patient’s condition and response to the medication. It is important to follow the prescribed dosage and not to self-administer the injection. The medication should be taken at the same time each day to maintain a consistent level of the medicine in the body.

Fluanxol Depot is not recommended during pregnancy or breastfeeding. The medication can enter breast milk and may have potential risks to the developing fetus or infant. It is important to consult with a healthcare professional before using this medication if you are pregnant or breastfeeding.

To order Fluanxol Depot from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. The team will ask you to confirm your trade or institutional credentials and will reply with pricing, availability, shipping, and the import paperwork.

Fluanxol Depot is a typical antipsychotic that works by blocking dopamine receptors. It is used for the management of schizophrenia and depressive disorders. Compared to other antipsychotics, Fluanxol Depot may have a different side effect profile and efficacy. It is important to consult with a healthcare professional to determine the most suitable medication for your condition.

Fluanxol Depot should be stored in a cool and dry place, and the temperature should be kept below 30°C. It is important to protect the medication from light and to keep it out of reach of children. The medication should be administered by a healthcare professional and should not be self-administered.

Fluanxol Depot is administered as an intramuscular injection under the supervision of a healthcare professional. It should not be self-administered. The medication is given at the same time each day to maintain a consistent level of the medicine in the body. It is important to follow the prescribed dosage and not to skip any doses.

The most serious risks associated with Fluanxol Depot include neuroleptic malignant syndrome, which is characterized by hyperthermia, hypertonicity of skeletal muscles, unconsciousness, and autonomic nervous system instability. Other serious side effects include rigidity, tremors, restlessness, and tardive dyskinesia. It is important to consult with a healthcare professional if you experience any of these symptoms.

Fluanxol Depot should not be used by individuals who are hypersensitive to flupentixol or any of the excipients in the medication. It is also not recommended for extremely excitable and overactive patients, those with mania, porphyria, coma, preexisting CNS depression, bone-marrow suppression, or phaeochromocytoma. It is important to consult with a healthcare professional before using this medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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