Minims Fluoresceína Sódica Bausch + Lomb Ireland Limited (Fluorescein Sodium)

Fluorescein Sodium is employed in ophthalmic diagnostic procedures to assess the ocular surface and tear film.

• Corneal abrasions: enables visualization of epithelial defects for accurate assessment.
• Dry eye evaluation: highlights tear‑film breakup patterns to aid diagnosis of tear‑film instability.
• Contact lens fitting: reveals surface irregularities and debris to ensure proper lens placement.

• Fluorescein sodium is a water‑soluble dye that binds to proteins on the ocular surface. When applied, it preferentially stains areas where the corneal epithelium is disrupted or where the tear film is thin. Under cobalt‑blue illumination the stained regions appear bright green, allowing clinicians to detect abrasions, ulcerations, and tear‑film defects with enhanced contrast.

Fluorescein Sodium may cause transient ocular reactions, most of which are mild and self‑limiting.

Common Side Effects

• Mild eye irritation: temporary burning or stinging sensation.
• Transient redness: brief conjunctival hyperemia after instillation.
• Temporary blurred vision: resolves within minutes.
• Mild tearing: increased lacrimation that subsides quickly.

Serious or Rare Side Effects

• Severe allergic reaction: anaphylaxis or angioedema requiring immediate medical attention.
• Corneal edema: swelling of the cornea that may impair vision.
• Increased intra‑ocular pressure: notable rise in pressure necessitating monitoring.
• Toxic anterior segment syndrome: rare inflammatory response affecting the anterior chamber.

When using Fluorescein Sodium, consider the following safety measures.

• Allergy assessment: verify no known hypersensitivity to fluorescein or sodium salts.
• Pregnancy: use only if the potential benefit justifies the unknown risk.
• Contact lenses: remove lenses before instillation to avoid staining and discomfort.
• Concurrent ocular medications: avoid mixing with other eye drops without professional guidance.
• Storage: Store at room temperature below 25°C: keep in the original container, protect from light and moisture.

Fluorescein Sodium can interact with certain ophthalmic agents; review the following.

Major Interactions (Avoid)

• Topical anesthetics: may increase corneal toxicity when combined.
• Phenylephrine eye drops: can cause excessive pupil dilation and discomfort.

Moderate Interactions (Monitor Closely)

• Other ophthalmic dyes: may alter staining patterns and interpretation.
• Systemic antihistamines: can affect tear production and influence test results.
• Contact lens solutions: may interfere with fluorescein staining efficacy.