Product image of Minims Natriumfluoresceïne Bausch + Lomb Ireland Limited (Fluorescein Sodium) supplied by GNH India

Minims Natriumfluoresceïne Bausch + Lomb Ireland Limited

Active Ingredient:
Fluorescein Sodium
Origin:
EU

Minims Natriumfluoresceïne Bausch + Lomb Ireland Limited (Fluorescein Sodium)

Fluorescein Sodium, the active ingredient in Minims Natriumfluoresceïne Bausch + Lomb Ireland Limited, is a diagnostic ophthalmic agent presented as a sterile aqueous solution for ocular use. It highlights corneal epithelial defects and tear‑film irregularities, facilitating clinical assessment in patients of all ages.

GNH India supplies Minims Natriumfluoresceïne Bausch + Lomb Ireland Limited as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution.

Manufacturer / TM Owner

Bausch + Lomb Ireland Limited

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Indications & Clinical Uses

  • Fluorescein Sodium is used in ophthalmology to evaluate the ocular surface and detect epithelial defects.
  • Corneal abrasions: stains the damaged epithelium to delineate the size and depth of the abrasion.
  • Dry eye assessment: highlights areas of tear‑film breakup for diagnostic evaluation.
  • Contact lens fitting: reveals surface irregularities that may affect lens tolerance.
  • Foreign body detection: assists in locating retained particles on the cornea.
  • Surgical planning: visualizes epithelial integrity before refractive procedures.

How It Works

  • Fluorescein Sodium binds to plasma proteins and extracellular matrix on the ocular surface. When illuminated with cobalt‑blue light, it emits a bright green fluorescence, allowing clinicians to visualize disruptions in the corneal epithelium and irregularities in the tear film. The fluorescence intensity correlates with the extent of epithelial loss, providing a rapid, non‑invasive diagnostic signal.

Side Effects

Adverse reactions are generally mild and transient.

Common Side Effects

  • Transient ocular stinging or burning sensation.
  • Mild conjunctival hyperemia (redness).
  • Temporary yellow discoloration of tears and surrounding skin.

Serious or Rare Side Effects

  • Allergic hypersensitivity reaction, including swelling, itching, or rash.
  • Severe corneal toxicity in eyes with pre‑existing epithelial compromise.
  • Rare systemic reactions such as nausea or vomiting.

Precautions & Warnings

  • Proper use of Fluorescein Sodium requires attention to patient history and handling.
  • Allergy screening: confirm no known hypersensitivity to fluorescein or similar dyes.
  • Pregnancy and lactation: use only if clearly needed, as safety data are limited.
  • Contact lens wearers: remove lenses before application to avoid staining.
  • Concurrent ocular medications: avoid use with agents that may alter corneal integrity.
  • Interpretation caution: excessive staining may obscure clinical view.
  • Store at ambient temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Fluorescein Sodium may interact with other ocular agents, affecting safety or diagnostic accuracy.

Major Interactions (Avoid)

  • Topical anesthetics: may increase corneal toxicity when combined with fluorescein.
  • Anticholinergic eye drops: can reduce tear film, affecting staining pattern.

Moderate Interactions (Monitor Closely)

  • Systemic antihistamines: may cause dry eye, altering test results.
  • Ocular steroids: may affect epithelial healing, requiring careful assessment.
  • Diagnostic dyes (e.g., rose bengal): concurrent use may cause additive staining.

Frequently Asked Questions

Minims Natriumfluoresceïne is an ophthalmic diagnostic solution containing Fluorescein Sodium. It is applied to the eye to highlight corneal epithelial defects, assess tear‑film stability, and aid in the detection of foreign bodies or surface irregularities during eye examinations.

Fluorescein Sodium adheres to damaged epithelial cells and, when illuminated with cobalt‑blue light, emits a bright green fluorescence. This fluorescence makes areas of epithelial loss or tear‑film breakup visible, allowing clinicians to quickly identify and evaluate ocular surface pathology.

The dose and frequency are determined by the prescribing eye‑care professional based on the specific diagnostic need. Typically, a single drop is instilled onto the ocular surface, but the exact regimen should follow the clinician’s instructions.

Safety data for Fluorescein Sodium in pregnancy and lactation are limited. It should be used only if clearly indicated and after a risk‑benefit assessment by the health‑care provider. Women who are pregnant or breastfeeding should discuss potential risks with their clinician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Fluorescein Sodium provides rapid, high‑contrast green fluorescence and is widely used for corneal abrasion detection. Alternatives such as Rose Bengal or Lissamine Green stain damaged cells differently and may cause more irritation. Fluorescein is generally preferred for quick screening because of its ease of use and lower discomfort.

Store the product at ambient temperature, preferably below 25 °C, in its original sealed container. Protect it from direct sunlight and moisture. Avoid freezing, and keep the vial tightly closed when not in use to maintain sterility and fluorescence integrity.

The solution is administered as an ocular drop. The prescriber or trained eye‑care professional instills a single drop onto the conjunctival sac, allowing it to spread across the corneal surface. After a brief waiting period, the eye is examined under cobalt‑blue illumination to assess staining.

Serious risks, though rare, include allergic hypersensitivity reactions such as swelling, itching, or rash, and severe corneal toxicity in eyes with pre‑existing epithelial compromise. Any signs of significant discomfort, vision change, or systemic symptoms should prompt immediate medical evaluation.

Patients with a known allergy to fluorescein or any component of the formulation should avoid use. Individuals with severe ocular surface disease, active infection, or compromised corneal epithelium should only use the product under close supervision of an eye‑care professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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