Product image of Mentocaína Anti-Inflam (Flurbiprofen) supplied by GNH India

Mentocaína Anti-Inflam

Active Ingredient:
Flurbiprofen
Origin:
EU

Mentocaína Anti-Inflam (Flurbiprofen)

Flurbiprofen, the active ingredient in Mentocaína Anti-Inflam, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oromucosal formulation for local use. It is employed to alleviate pain and reduce inflammation in adult patients with musculoskeletal conditions.

GNH India supplies Mentocaína Anti-Inflam as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards, provides regulatory support for global distribution, and ensures reliable supply chains to maintain product integrity across diverse markets.

Manufacturer / TM Owner

Laboratórios Azevedos - Indústria Farmacêutica, S.A.

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Indications & Clinical Uses

Flurbiprofen, an NSAID, acts on the cyclooxygenase pathway to relieve pain and inflammation.

  • Rheumatoid arthritis: reduces joint pain, swelling, and stiffness
  • Osteoarthritis: alleviates chronic joint discomfort and improves mobility
  • Acute musculoskeletal pain: provides short‑term relief of pain and inflammation

How It Works

  • Flurbiprofen reversibly inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. By lowering prostaglandin synthesis, it reduces peripheral sensitization of nociceptors and diminishes inflammatory exudate formation, leading to analgesic and anti‑inflammatory effects at the site of administration.

Side Effects

Flurbiprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: mild stomach upset or dyspepsia
  • Nausea: feeling of queasiness that may lead to vomiting
  • Headache: mild to moderate pain in the head region
  • Dizziness: transient sensation of light‑headedness

Serious or Rare Side Effects

  • Severe gastrointestinal bleeding: may present as black stools or vomiting blood
  • Renal impairment: reduced kidney function, especially in at‑risk patients
  • Allergic skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis

Precautions & Warnings

When prescribing flurbiprofen, clinicians should consider several precautionary measures to minimize risk.

  • Renal function: monitor in patients with existing kidney disease
  • Cardiovascular risk: use cautiously in patients with heart disease
  • Gastrointestinal history: avoid in those with ulcer disease or prior GI bleeding
  • Concomitant anticoagulants: increased bleeding risk, require close monitoring
  • Pregnancy and lactation: safety not established; avoid unless essential
  • Store at ambient temperature: keep in original container, protect from moisture and light

Avoid Interactions

Flurbiprofen can interact with other medicines, influencing its safety and efficacy.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: may reduce renal function when combined
  • Diuretics: heightened risk of renal impairment
  • Lithium: NSAIDs may raise lithium serum concentrations

Frequently Asked Questions

Mentocaína Anti-Inflam contains flurbiprofen, an NSAID that is used to relieve mild to moderate pain and to reduce inflammation associated with conditions such as rheumatoid arthritis, osteoarthritis and acute musculoskeletal injuries.

Flurbiprofen blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are required for the synthesis of prostaglandins. By lowering prostaglandin levels, it diminishes inflammation, swelling, and the sensation of pain at the affected site.

The appropriate dose of Mentocaína Anti-Inflam is determined by the prescribing healthcare professional based on the patient’s condition, age, weight and overall health. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety of flurbiprofen in pregnancy and lactation has not been established. It should be avoided unless the potential benefit justifies the potential risk to the fetus or infant, and only under direct medical supervision.

Enquiries are submitted through the product page at gnhindia.com where you specify the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Flurbiprofen shares the core COX‑inhibiting mechanism of most NSAIDs but is often formulated for oromucosal delivery, offering rapid local action. Compared with ibuprofen or naproxen, it may provide quicker onset for oral mucosal pain, though overall efficacy and safety profiles are similar.

Store the product at ambient temperature, preferably below 25 °C. Keep it in the original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Mentocaína Anti-Inflam is applied to the oral mucosa as directed by a healthcare professional. The oromucosal route allows the medication to be absorbed through the lining of the mouth, providing localized pain relief.

Serious risks include gastrointestinal bleeding, severe renal impairment and rare but life‑threatening allergic reactions such as Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they notice blood in stool or vomit, sudden loss of kidney function, or severe skin rashes.

Individuals with a known hypersensitivity to flurbiprofen or other NSAIDs, active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or significant renal impairment should avoid using Mentocaína Anti-Inflam unless specifically advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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