Product image of Micetal Gél (Flutrimazole) supplied by GNH India

Micetal Gél

Active Ingredient:
Flutrimazole
Origin:
EU

Micetal Gél (Flutrimazole)

Flutrimazole, the active ingredient in Micetal Gél, is an azole antifungal presented as a gel for topical use. It treats dermatophyte infections and cutaneous candidiasis with mild to moderate severity and helps relieve associated itching. GNH India supplies Micetal Gél as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with consistent quality and regulatory adherence. The company provides reliable logistics and documentation for cross‑border shipments.

Manufacturer / TM Owner

Noucor Health, S.A.

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Indications & Clinical Uses

Flutrimazole is an azole antifungal that targets superficial fungal skin infections.

  • Dermatophyte infections: clears the infection, reduces scaling and itching.
  • Cutaneous candidiasis: eradicates Candida species on the skin and alleviates redness.
  • Superficial fungal infections: provides broad‑spectrum activity against common skin fungi, improving lesion healing.

How It Works

  • Flutrimazole exerts its antifungal effect by selectively inhibiting the cytochrome P450‑dependent enzyme lanosterol 14α‑demethylase, a key step in ergosterol synthesis. By blocking this pathway, the drug disrupts fungal cell membrane formation, leading to increased membrane permeability and ultimately cell death, while sparing human cells. This inhibition is concentration‑dependent and results in accumulation of toxic sterol intermediates within the fungal cell.

Side Effects

Topical application of Flutrimazole gel may be associated with local skin reactions.

Common Side Effects

  • Mild burning sensation: transient feeling of heat after application.
  • Transient itching: brief itchiness that resolves without treatment.
  • Redness at application site: localized erythema that diminishes within hours.
  • Dryness or peeling of skin: mild flaking of the treated area.
  • Stinging sensation: brief sharp discomfort on contact.
  • Mild irritation: slight discomfort without swelling.

Serious or Rare Side Effects

  • Contact dermatitis with swelling: allergic skin reaction causing edema and rash.
  • Severe allergic reaction such as angioedema: rapid swelling of deeper skin layers, potentially airway‑involving.
  • Blistering or ulceration of the treated area: formation of vesicles or open sores.
  • Systemic hypersensitivity reactions (rare): generalized rash, fever, or malaise.
  • Hepatic enzyme elevation (very rare): abnormal liver function tests requiring monitoring.

Precautions & Warnings

When using Micetal Gél, several precautions should be observed to ensure safety and effectiveness.

  • Apply to intact skin only: avoid broken or inflamed areas.
  • Avoid contact with eyes, mouth or mucous membranes: rinse thoroughly if accidental exposure occurs.
  • Do not use on extensive body surface: limit to affected areas to minimize systemic absorption.
  • Discontinue use if severe irritation or allergic reaction develops: seek medical advice promptly.
  • Known hypersensitivity to azole antifungals: contraindicated in such patients.
  • Store at room temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Flutrimazole gel may interact with other topical or systemic agents; awareness of these interactions helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Concurrent use with other topical azole antifungals: may increase local irritation.
  • Systemic azole therapy (e.g., itraconazole) combined with extensive gel use: potential for additive systemic exposure.

Moderate Interactions (Monitor Closely)

  • Co‑application with topical corticosteroids: may mask signs of infection progression.
  • Use under occlusive dressings: enhances drug absorption, increasing risk of side effects.
  • Combination with skin irritants (e.g., harsh soaps): could exacerbate local reactions.

Frequently Asked Questions

Micetal Gél is a topical gel containing the azole antifungal flutrimazole. It is indicated for the treatment of superficial fungal skin infections such as dermatophyte infections (e.g., tinea corporis, tinea pedis) and cutaneous candidiasis. The gel is applied directly to the affected area to reduce fungal growth, alleviate symptoms, and promote healing.

Flutrimazole works by inhibiting the fungal enzyme lanosterol 14α‑demethylase, which is essential for converting lanosterol to ergosterol, a key component of the fungal cell membrane. By blocking this step, the drug disrupts membrane synthesis, leading to accumulation of toxic sterol intermediates, increased membrane permeability, and ultimately fungal cell death while having minimal effect on human cells.

The dosage of Micetal Gél is determined by the prescribing healthcare professional based on the type and extent of the fungal infection. Typically, a thin layer is applied to the cleaned skin once or twice daily for the period recommended by the clinician. Patients should follow the specific instructions provided on the prescription label.

The safety of flutrimazole topical gel in pregnancy or while breastfeeding has not been definitively established, and the product’s pregnancy category is listed as unknown. Healthcare providers should weigh the potential benefits against any possible risks and consider alternative treatments if appropriate. Pregnant or nursing patients should discuss use with their physician.

To request Micetal Gél, visit the product page on gnhindia.com and submit an enquiry specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, and will ask for trade or institutional credentials. The sales team then replies with pricing, availability, shipping details and any necessary import documentation.

Compared with other topical antifungals such as terbinafine or clotrimazole, flutrimazole offers a broad spectrum against dermatophytes and Candida species and works via a distinct mechanism targeting lanosterol 14α‑demethylase. Clinical choice depends on pathogen susceptibility, formulation preference, and patient tolerance. Some clinicians may prefer Micetal Gél for its gel base, which can be advantageous for moist or intertriginous areas.

Micetal Gél should be stored at room temperature, below 25 °C, in its original container to protect it from moisture, heat and direct sunlight. The packaging is designed to maintain product stability; therefore, it should not be frozen or exposed to extreme temperatures. Keep the gel out of reach of children and handle with clean hands to avoid contamination.

Before application, the affected skin area should be gently cleaned and dried. A thin layer of Micetal Gél is then spread over the lesion and surrounding skin, usually once or twice daily as directed by the prescriber. Hands should be washed after use, and the treated area should be allowed to air‑dry before covering with clothing or dressings, unless otherwise advised.

Although rare, serious adverse reactions can include contact dermatitis with swelling, severe allergic responses such as angioedema, blistering or ulceration of the skin, systemic hypersensitivity, and, very rarely, hepatic enzyme elevation. Patients should discontinue the gel and seek immediate medical attention if they experience signs of a severe reaction, such as extensive swelling, difficulty breathing, or persistent skin breakdown.

Micetal Gél is contraindicated in individuals with a known hypersensitivity to flutrimazole or any other azole antifungal agents. It should also be avoided on broken, inflamed or infected skin not caused by fungi, and in patients who have experienced severe allergic reactions to similar topical products. Pregnant or breastfeeding women should consult their healthcare provider before use, and the gel should not be applied to the eyes, mouth or mucous membranes.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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