Product image of Inuνair Nexthaler (Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous) supplied by GNH India

Inuνair Nexthaler

Active Ingredient:
Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous
Origin:
EU

Inuνair Nexthaler (Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous)

Formoterol fumarate dihydrate / beclometasone dipropionate, the active ingredient in Inuνair Nexthaler, is a Long‑acting β2‑adrenergic agonist (LABA) / inhaled corticosteroid (ICS) combination presented as a dry powder inhaler (Nexthaler) for inhalation use. It treats asthma and chronic obstructive pulmonary disease in adult patients.

GNH India supplies Inuνair Nexthaler as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Chiesi Hellas S.A.

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Indications & Clinical Uses

  • Inuνair Nexthaler combines a LABA and an inhaled corticosteroid to manage chronic airway diseases.
  • Asthma: improves airflow and reduces airway inflammation for long‑term control.
  • COPD: enhances lung function and helps prevent exacerbations in chronic obstructive pulmonary disease.
  • Chronic bronchitis (COPD component): decreases mucus production and improves breathing comfort.

How It Works

  • Formoterol binds to β2‑adrenergic receptors on airway smooth muscle, causing prolonged relaxation and bronchodilation, while beclometasone enters cells and binds glucocorticoid receptors, modulating gene transcription to suppress inflammatory cytokines, reduce edema, and inhibit immune cell activation, together providing sustained airway opening and anti‑inflammatory protection.

Side Effects

Inuνair Nexthaler may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Throat irritation or soreness
  • Cough or wheezing after inhalation
  • Hoarseness or voice changes
  • Oral candidiasis (thrush)
  • Headache
  • Nasopharyngitis

Serious or Rare Side Effects

  • Paradoxical bronchospasm
  • Severe allergic reaction (anaphylaxis)
  • Adrenal suppression with prolonged use
  • Pneumonia in COPD patients
  • Decreased bone mineral density
  • Cataract formation

Precautions & Warnings

  • When prescribing Inuνair Nexthaler, clinicians should observe several precautions to ensure safe use.
  • Monitor lung function: perform regular spirometry to assess therapeutic response.
  • Assess for oral thrush: advise patients to rinse mouth after each dose.
  • Avoid abrupt discontinuation: taper under medical supervision to prevent loss of control.
  • Use with caution in cardiovascular disease: evaluate risk of tachycardia or arrhythmia.
  • Store at ambient temperature below 25°C: keep in original pack, protect from moisture.

Avoid Interactions

Inuνair Nexthaler can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Beta‑blockers: may diminish bronchodilator effect of formoterol.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole): can increase systemic exposure to beclometasone.

Moderate Interactions (Monitor Closely)

  • Diuretics: may exacerbate hypokalemia when combined with LABA.
  • Theophylline: additive bronchodilator effect may increase side‑effects.
  • Anticholinergic inhalers: combined use may increase dry mouth and throat irritation.

Frequently Asked Questions

Inuνair Nexthaler is prescribed for the long‑term management of asthma and chronic obstructive pulmonary disease (COPD). It combines a bronchodilator with an anti‑inflammatory agent to improve airflow, reduce symptoms, and lower the risk of exacerbations in adult patients with these chronic respiratory conditions.

Formoterol fumarate dihydrate is a long‑acting β2‑adrenergic agonist. It binds to β2 receptors on airway smooth muscle, activating adenylate cyclase, increasing cyclic AMP, and causing sustained relaxation of the bronchial muscles. This results in prolonged bronchodilation, helping keep the airways open for symptom control.

The exact dosing regimen for Inuνair Nexthaler is determined by the prescribing healthcare professional based on the patient’s disease severity, age, and response to therapy. Typically, the inhaler is used twice daily, but the prescriber will provide specific instructions tailored to each individual.

Safety data for Inuνair Nexthaler in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss treatment options with their physician.

To request Inuνair Nexthaler, visit the product page on gnhindia.com and submit an enquiry with the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Inuνair Nexthaler offers a comparable efficacy profile to other LABA/ICS combinations, delivering both bronchodilation and anti‑inflammatory effects. Its Nexthaler dry‑powder device provides consistent dose delivery and may be preferred by patients who find breath‑actuated inhalers easier to use than metered‑dose sprays.

Store the inhaler at ambient temperature below 25 °C, protected from moisture and direct sunlight. Keep it in the original packaging until use, and avoid exposing it to extreme heat or humidity, which could affect dose consistency and device performance.

Inuνair Nexthaler is a dry‑powder inhaler. The patient should open the device, exhale fully away from the inhaler, place the mouthpiece in the mouth, and inhale quickly and deeply through the device. After inhalation, hold the breath for about 5–10 seconds before exhaling.

Serious risks include paradoxical bronchospasm, severe allergic reactions such as anaphylaxis, adrenal suppression with long‑term use, and an increased incidence of pneumonia in COPD patients. Patients should seek immediate medical attention if they experience sudden worsening of breathing or signs of an allergic reaction.

Inuνair Nexthaler should be avoided in individuals with known hypersensitivity to formoterol, beclometasone, or any excipients in the inhaler. Caution is advised for patients with certain cardiovascular disorders, uncontrolled hypertension, or a history of severe allergic reactions. Use in children is only appropriate if the product is approved for that age group.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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