Glimepiride Teva Uk (Glimepiride)

Glimepiride Teva Uk is indicated for the treatment of type 2 diabetes mellitus as part of a comprehensive diabetes management plan that includes diet and exercise.

• Improves glycaemic control when used alone or in combination with other oral antidiabetic agents.
• May be prescribed when metformin alone does not achieve target HbA1c levels.
• Suitable for adult patients with adequate pancreatic beta‑cell function.
• Can be used in patients who require a once‑daily oral therapy.
• Often considered after lifestyle modifications have been implemented.

Glimepiride Teva Uk may cause a range of side effects, most of which are mild to moderate in severity.

Common

• Hypoglycaemia (low blood sugar)
• Nausea or abdominal discomfort
• Headache
• Dizziness
• Weight gain
• Skin rash or itching

Serious

• Severe hypoglycaemia leading to loss of consciousness
• Allergic reactions such as angio‑edema or Stevens‑Johnson syndrome
• Hepatic dysfunction
• Hematologic abnormalities (e.g., leukopenia, thrombocytopenia)

Before starting Glimepiride Teva Uk, certain precautions should be considered to ensure safe use.

• Assess renal and hepatic function; dose adjustment may be required.
• Use cautiously in elderly patients due to increased risk of hypoglycaemia.
• Contraindicated in patients with known sulfonylurea hypersensitivity.
• Monitor blood glucose regularly, especially when initiating therapy or changing dose.
• Pregnancy category B: discuss risks and benefits with a healthcare provider.
• Avoid use in patients with severe cardiac disease without medical supervision.

Glimepiride Teva Uk can interact with several medicines, affecting its efficacy or safety.

Avoid

• Other sulfonylureas or insulin, which may increase hypoglycaemia risk.
• Strong CYP2C9 inhibitors (e.g., fluconazole, amiodarone) that can raise glimepiride plasma levels.
• MAO‑B inhibitors, which may potentiate hypoglycaemic effects.

Use with caution

• Beta‑blockers, which may mask hypoglycaemia symptoms.
• Thiazide diuretics, which can affect glucose tolerance.
• Corticosteroids, which may increase blood glucose and require dose adjustments.
• Alcohol, as it can potentiate hypoglycaemia.