Glucagen Hypokit (Glucagon)

Glucagen Hypokit is indicated for the rapid reversal of severe hypoglycemia when oral carbohydrate intake is not possible or ineffective.

• Administration to adults and children experiencing insulin‑induced hypoglycemia unresponsive to oral glucose.
• Emergency treatment for hypoglycemic episodes in patients with type 1 or type 2 diabetes.
• Use when a rapid increase in blood glucose is required to prevent loss of consciousness.
• Applicable in clinical settings such as hospitals, ambulances, or home care during diabetic emergencies.
• Suitable for patients who are unable to swallow or have impaired gastric absorption.

Glucagen Hypokit may cause transient physiological responses related to its glucose‑raising action.

Common

• Nausea or vomiting
• Flushing or warmth at the injection site
• Transient headache
• Mild abdominal discomfort

Serious

• Allergic reaction including rash, itching, or swelling
• Severe hypotension or cardiovascular collapse (rare)
• Pancreatitis (very rare)

Before using Glucagen Hypokit, healthcare providers should consider several precautionary factors to ensure safe administration.

• Confirm diagnosis of severe hypoglycemia and assess the need for injectable glucagon.
• Avoid use in patients with known hypersensitivity to glucagon or any kit components.
• Monitor blood glucose levels after administration to verify therapeutic response.
• Exercise caution in patients with pheochromocytoma, adrenal insufficiency, or recent myocardial infarction.
• Do not reuse the syringe; discard all components after a single use.
• Pregnancy and lactation status should be evaluated, as safety data are limited.
• Store the product according to manufacturer instructions, protecting it from extreme temperatures.

Glucagen Hypokit can interact with other medications or conditions that affect glucose metabolism or cardiovascular stability.

Avoid

• Concurrent use of beta‑blockers that may mask typical glucagon‑induced symptoms.
• Co‑administration with insulin analogs in excess, which could exacerbate hypoglycemia after glucagon effect wanes.

Use with caution

• Patients receiving oral contraceptives or hormone therapy, as glucagon may alter hormone levels.
• Individuals on anticoagulants, because intramuscular injection could increase bleeding risk.
• Use in patients with severe renal or hepatic impairment, monitoring for prolonged effects.