Glucagen Hypokit (Glucagon)

Glucagen Hypokit is indicated for the acute management of conditions that cause dangerously low blood glucose.

• Treatment of severe hypoglycemia in patients with diabetes when oral glucose is ineffective or unavailable.
• Emergency reversal of insulin overdose in both adults and children.
• Use in a clinical setting when rapid restoration of blood glucose is required, such as during surgery or diagnostic procedures.
• Administration by trained personnel in out‑of‑hospital situations, including home or workplace emergencies.
• Support for patients who are unconscious or unable to swallow oral carbohydrate preparations.
• Provision of a rapid, non‑oral glucose source when intravenous dextrose infusion is not immediately accessible.

Glucagen Hypokit may cause a range of adverse reactions, most of which are transient and resolve without intervention.

Common

• Nausea or vomiting, usually mild and short‑lasting.
• Flushing, warmth, or redness of the face and neck.
• Headache that resolves within a few hours.
• Dizziness or light‑headedness, especially when standing quickly.
• Transient sweating or feeling of heat that usually subsides quickly.

Serious

• Severe allergic reaction (anaphylaxis) presenting with rash, itching, swelling, or breathing difficulty.
• Rapid heart rate (tachycardia) or irregular heartbeat that may require monitoring.
• Low blood pressure (hypotension) leading to fainting or dizziness.
• Seizures or convulsions, which are very rare but require immediate medical attention.
• Chest pain or discomfort that may indicate cardiac involvement and should be evaluated.

When using Glucagen Hypokit, certain precautions and warnings should be observed to ensure safe and effective treatment.

• Verify the correct patient and indication before administration.
• Ensure the solution is clear and free of particles; do not use if discolored or contaminated.
• Use only with a new, sterile needle and syringe as supplied.
• Monitor blood glucose levels after administration and repeat dosing if hypoglycemia persists.
• Be aware of possible allergic reactions; discontinue use and seek medical help if signs of anaphylaxis appear.
• Store the kit according to the label, protecting it from extreme temperatures and light.
• Do not administer to patients with known hypersensitivity to glucagon or any excipients.

Glucagen Hypokit may interact with certain medications or substances; awareness of these interactions helps prevent adverse outcomes.

Avoid

• Concurrent use with beta‑blockers may mask typical symptoms of hypoglycemia after glucagon administration.

Use with caution

• Caution when administered with other antihypoglycemic agents, as rapid glucose rise can lead to rebound hyperglycemia.
• Use carefully in patients receiving catecholamines, as glucagon can potentiate cardiovascular effects.
• Monitor closely if the patient is on MAO inhibitors, although significant interaction is uncommon.
• Consider dose adjustment if the patient is receiving high‑dose insulin therapy.
• Avoid simultaneous administration with other glucagon‑containing products to prevent overdose.